Chelonian Research Foundation https://www.acgpublishing.com/index.php/CCB <h1>About Chelonian Research Foundation</h1> <p align="justify">Chelonian Research Foundation, established in 1992 in Lunenburg, Massachusetts, is a non-profit IRS-designated 501(c)(3) tax-exempt private operating foundation established for the purposes of producing and publishing scientific research on turtles and tortoises of the world, as well as supporting worldwide turtle and tortoise research through charitable distributions to associated independent scientific investigators or research organizations that produce specific research consistent with the stated objectives of the Foundation. The Foundation was established partly in response to the rapidly deteriorating natural environment and its deleterious effects on populations of turtles and tortoises of the world as well as the threatening effects of direct human exploitation on turtles and tortoises around the world, and partly in response to the global need for systematic scientific investigations and documentation of the diversity of these animals. The broad purpose of the Foundation is to become involved where the energies of concerned and talented individuals and the application of resources may reasonably be anticipated to provide a scientific basis to allow for potential improvement in conditions or increased understanding of turtles and tortoises.</p> <p align="justify"> </p> Chelonian Research Foundation en-US Chelonian Research Foundation 1071-8443 MIGRANT LABOUR UPSKILLING – ISSUES AND CHALLENGES FOR SKILL DEVELOPMENT INITIATIVES: https://www.acgpublishing.com/index.php/CCB/article/view/374 <p>Today the world is moving towards skill and technology. All sectors are increasingly embracing skilled manpower. Employment protection and opportunity for better earnings are all possible with skilling. Labour productivity can also be achieved with skilling. It is critical from both the socio-economic and demographic points of view. It is an important tool for reducing poverty, enhancing competitiveness and employability and to promote the self-entrepreneurship among youths. However, majority of the workers are employed in the unorganized sector. Working in this unorganized sector provides not much scope for improvement. Migrants constitute a large segment working in the unorganized sector. It is also a well-known fact that because of their inherent drawbacks they are forced to work in the unorganized sector and are exploited. The system of finding work through agents and other means has its own misgivings. They are continuously getting exploited due to the intermediaries in the labour market. The migrant workers face lot of challenges in getting good education, skill training and employment. It is here that the government should step in, if at all they want to make use of the so-called demographic dividend. The government has no doubt taken a great step in this direction by setting up a ministry for skilling and training. Crores of money has been spent on training and placements but the vast majority are still unaware of this herculean effort.&nbsp; The major issue with unskilled migrants is that they are unable to work in the organised sector, which necessitates upskilling. India is not only poised for growth but is growing at a magical pace. When the world is reeling under financial crises, our country is the sun among stars. It is the human resources that has led us to this growth. While skilling and upskilling have all proved its relevance, the government has shown its commitment by enhancing the allocation to skill development initiatives in the present budget. The migrants have expressed their willingness to get trained if some of the bottlenecks are removed. They have stated that the most significant constraints they face are a lack of time after working hours and the possibility of losing daily wages. They are in favour of on-the-job training. However, the unorganized sector does not encourage such training facilities.&nbsp; The government has to bring about a big change in the reach aspect. Also, all these initiatives should be aggressively promoted in the rural areas.</p> <p><strong>Key Words: </strong>Migration, Skill development, Government Initiatives.</p> Dr. Rajini, Dr.M.M.Bagali, Vidya S.Patil Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-13 2024-04-13 19 01 500 510 RUTA CHALEPENSIS LEAF EXTRACT'S PROTECTS METABOLIC INDICES ABNORMALITIES, TYPE 2 DIABETES, AND VARIOUS ORGANS TOXICITIES IN OBESE RAT https://www.acgpublishing.com/index.php/CCB/article/view/822 <p>Plant phenolics have been used as food supplements due to their capacity to prevent several ailments<em>. </em><strong>Aim:</strong>The effects of Ruta chalepensis extract (RCE) on α-amylase activity, type 2 diabetes, and lipid profile induced by obesity.<strong>Methods</strong><em>: </em>obesity was induced by a high-fat, high-fructose diet.&nbsp; Obese rats were given either RCEor acarbose daily by gastric gavage. <strong>Results</strong>:In a dosage-dependent manner, Ruta chalepensis extracts dramatically reduced pancreatic α-amylase activity in in vitro research<em>.</em>. RCE therapy in obese rats decreased blood glucose levels by 22% by decreasing the activities of intestinal, pancreatic, and blood α-amylase by 25, 22, and 27%, respectively and improved insulin sensitivity evidenced by oral glucose tolerance test (OGTT). Additionally, biochemical analysis and histological examination demonstrated that giving RCE to those with type 2 diabetes who had been exposed to HFFD corrected their lipid profiles and preserved their liver and kidney functions.<strong>Conclusion</strong>:This study shows that RCE is a beneficial functional food for diabetics due to its ability to control lipid profiles, blood glucose levels, and protect against liver and kidney toxicity.</p> <p><strong>Keywords: </strong><em>Ruta chalepensis</em>, type 2 diabetes, lipid profile, α-amylase</p> <p><strong>Running title:</strong>Ruta chalepensis, diabetes and liver-kidney functions in obese rat</p> Ferjeni Zouidi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-27 2024-04-27 19 01 675 685 ASSESSMENT OF THE IMPACT OF PLANT BASED MEAT ALTERNATIVES ON CONSUMER HEALTH & ENVIRONMENT https://www.acgpublishing.com/index.php/CCB/article/view/842 <p>The increased scrutiny of meat production and consumption practices, primarily in Western societies, has resulted in growing awareness regarding the environmental and health implications associated with these practices. Meat production, despite being a significant contributor to global greenhouse gas emissions and utilizing vast land resources, provides less than 20% of total calories and 40% of protein.This study examines the nutritional, consumer, and environmental aspects of plant-based meat alternatives (PBMAs). It highlights the emergence of innovative substitutes, such as fungal-based mycoproteins, which exhibit promising nutritional profiles and reduced environmental footprints compared to conventional meat. Further, it investigates the nutritional differences between PBMAs and traditional meat products, revealing significant variations in protein content, amino acid concentrations, and bioavailability.</p> <h1>&nbsp;</h1> <h1>The research objectives encompass nutritional comparison, consumer perception, and environmental sustainability. By providing comprehensive insights into the evolving landscape of alternative protein sources, the study informs stakeholders and guides decision-making in food production and consumption, contributing to the broader discourse on sustainability and health-conscious diets.</h1> <h1>&nbsp;</h1> <h1>Keywords: Mycoprotein, consumer perception, nutritional profile, Meat Substitutes, Dietary Trends</h1> Misbah Mahtab, Madiha Rohi, Rashida Perveen, Tabeen Irfan, Noor Ul Ain Shah Rameen Zahra, Sadaf Javaria, Muhammad Suleman Najib, Muhammad Ali Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-11 2024-06-11 19 01 900 919 WATER HYACINTH MEDIATES THE CREATION OF SILVER NANOPARTICLES AND THEIR USAGE FOR PHOTOCATALYTIC DYE DEGRADATION STUDIES https://www.acgpublishing.com/index.php/CCB/article/view/858 <p>This investigation employed water hyacinth leaf extract. The creation of silver nanoparticles was identified by a color shift from pale yellow to brown, followed by a peak in the UV spectrum. Functional groups are identified by FTIR analysis. The peaks ranged between 400 and 3251 cm<sup>-1</sup>. The greatest peak consists of C-N and C-C stretching. The band was formed by the stretching of O-H groups in water, alcohol, and phenols. The silver particles were utilized to break down the methylene blue (MB) dye, which is harmful to both aquatic and human life. The MB dye was totally destroyed after 48 hours (2 days). The photocatalytic destruction of methylene blue with nanoparticles demonstrated the feasibility of utilizing nanoparticles for water purification.</p> Mona Jaiswal, Shilpi Shrivastava Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-22 2024-07-22 19 01 1092 1101 BIOACCUMULATION OF HEAVY METALS IN FISHES (CATLA CATLA AND TILAPIA MOZAMBIQUE) OF LAKSHMINARAYANA LAKE, EDULABAD, HYDERABAD, TELANGANA https://www.acgpublishing.com/index.php/CCB/article/view/874 <p>&nbsp;Heavy metals such as lead (Pb), cadmium (Cd), mercury (Hg), and arsenic (As) are persistent environmental pollutants. Unlike organic pollutants, heavy metals are non-biodegradable and can accumulate in aquatic ecosystems, leading to long-term ecological consequences (Shahjahan et al., 2022). These metals can enter water bodies through various pathways, including industrial effluents, agricultural runoff, and atmospheric deposition. Once in the aquatic environment, heavy metals can be taken up by aquatic organisms, leading to bioaccumulation and biomagnification through the food chain (Hayati et al., 2017). Fish are particularly susceptible to heavy metal contamination due to their position in the aquatic food web. They can accumulate heavy metals in their tissues, including muscle, liver, and gills, which can have detrimental effects on their health and survival (Suhendrayatna et al., 2002). Catla catla and Tilapia mozambique are two fish species commonly found in Lakshminarayana Lake. These species are important not only for their ecological roles but also for their economic value as a source of food for local communities.</p> <p><em>Catla catla</em> is commonly known as the Indian carp or catla fish, is a freshwater species native to the Indian subcontinent. Its robust, elongated body features a slightly convex dorsal profile, and its coloration ranges from silver to light gray. Notably, the head lacks scales, and the mouth is large and upturned, adapted for surface feeding (Avigliano et al., 2019). Barbels near the mouth aid in sensory perception. The dorsal fin displays a distinct black margin. Ecologically, <em>Catla catla</em> plays a vital role as an herbivorous filter feeder, consuming phytoplankton, algae, and detritus. However, its significance extends beyond ecological dynamics. Tilapia is scientifically known as <em>Oreochromis mossambicus</em>, is a freshwater fish species native to southeastern Africa and Asia. Its robust, elongated body features a slightly compressed shape. The coloration of <em>Tilapia mozambique</em> varies, ranging from silvery-gray to olive-brown. Ecologically, <em>Tilapia mozambique</em> plays a vital role as an herbivorous filter feeder, consuming phytoplankton, algae, and detritus. However, its significance extends beyond ecological dynamics (Virk et al., 2003). Bioaccumulated heavy metals pose health risks to both the fish and humans who consume them. Chronic exposure may lead to organ damage, impaired growth, reproductive issues, and compromised immune function. Monitoring <em>Tilapia mozambique</em> helps evaluate environmental pollution and potential human health hazards, emphasizing the delicate balance between aquatic ecosystems and our well-being.</p> <p>Chronic exposure may lead to organ damage, impaired growth, reproductive issues, and compromised immune function (El Shafei et al., 2016). Monitoring <em>Catla catla</em> helps evaluate environmental pollution and potential human health hazards, emphasizing the delicate balance between aquatic ecosystems and our well-being. Understanding the levels of heavy metals in Lakshminarayana Lake and their accumulation in fish tissues is crucial for evaluating the ecological health of the lake and the safety of fish consumption for local communities. This research will contribute to the development of effective management strategies to mitigate heavy metal pollution, protect aquatic life, and safeguard human health. While heavy metal contamination in fish is a well-documented phenomenon, this study is unique in its focus on the specific fish species prevalent in Lakshminarayana Lake—<em>Catla catla</em> and <em>Tilapia mozambique</em>. By analyzing heavy metal concentrations in the muscle, liver, and gill tissues of these species, the research offers a detailed view of bioaccumulation patterns that has not been previously explored in this context.</p> B. Prameela, B. Jyothi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-10 2024-08-10 19 01 1386 1395 ASSESSMENT OF INSECT DIVERSITY (HEMIPTERA & COLEOPTERA) IN HIMAYAT SAGAR AND OSMAN SAGAR LAKES OF HYDERABAD TELANGANA. https://www.acgpublishing.com/index.php/CCB/article/view/893 <p><strong>&nbsp;</strong><br>This study investigates the diversity of Hemiptera and Coleoptera in Himayat Sagar and Osman Sagar lakes during monsoon 2023. We recorded a total of 47 species at each lake, with Himayat Sagar showing higher species richness and more even distribution compared to Osman Sagar. The Shannon-Wiener and Simpson’s indices were used to quantify diversity and evenness, revealing that Himayat Sagar supports a more balanced and diverse insect community. These findings highlight the impact of environmental conditions on insect populations and provide recommendations for conservation.</p> Suprabha Panda, Dr. Deepa Jaiswal, Prof. Vanita Das, Prof. M. Madhavi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-22 2024-08-22 19 01 1501 1512 THE CHALLENGES POSED BY AI-GENERATED MISINFORMATION IN THE MEDIA AND ITS POTENTIAL EFFECTS ON LEGAL PROCEEDINGS https://www.acgpublishing.com/index.php/CCB/article/view/913 <p style="text-align: justify; line-height: 115%;"><span lang="EN-IN">As artificial intelligence (AI) technologies advance, the generation of misinformation has become increasingly sophisticated and pervasive within electronic media. This paper examines the challenges posed by AI-generated misinformation and its potential effects on legal proceedings. AI systems, particularly those utilizing deep learning techniques, can create hyper-realistic content, including text, images, and videos that misrepresent facts or fabricate events. Such misinformation can lead to significant public misperception regarding ongoing legal cases, potentially influencing jury pools and public opinion.</span></p> <p style="text-align: justify; line-height: 115%;"><span lang="EN-IN">The paper explores several dimensions of this issue, including the mechanisms through which AI-generated misinformation spreads, the role of social media platforms in amplifying these false narratives, and the psychological impact on audiences. Furthermore, it discusses how this misinformation can interfere with the right to a fair trial, compromising the integrity of legal proceedings. Specifically, we analyze cases where juror bias has been exacerbated by misleading media portrayals, leading to unjust outcomes.</span></p> <p style="text-align: justify; line-height: 115%;"><span lang="EN-IN">Moreover, the research delves into the legal implications of misinformation, addressing the challenges faced by courts in distinguishing between authentic and fabricated evidence. The paper also considers the responsibilities of media organizations and technology companies in mitigating the dissemination of AI-generated misinformation and the potential need for new regulatory frameworks.</span></p> <p style="text-align: justify; line-height: 115%;"><span lang="EN-IN">Ultimately, this paper aims to raise awareness about the intersection of AI, media, and the judiciary, emphasizing the urgent need for strategies to combat misinformation. By fostering a deeper understanding of these challenges, stakeholders can better safeguard the integrity of the legal system in an increasingly digital age.</span></p> Anjum Saxena Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-30 2024-09-30 19 01 1697 1712 ENSHRINEMENT SPATIAL PATTERN IN BUMIAYU TEMPLES (DESCRIPTION OF ENVIRONMENTAL ADAPTATION IN WET LAND) https://www.acgpublishing.com/index.php/CCB/article/view/190 <p>The Bumiayu temple is located in wetlands, but the temples are protected from puddles. The problem that arises are a) how is the location of Bumiayu temples, b) how is the network in Bumiayu temples area and c) how is the distribution of the Bumiayu temples. The purpose of this study was to analyze the spatial pattern of the Bumiayu enshrinement which shows that the people-built temples had adapted to nature. The specific aims are to analyze the morphography, morphometry, landform of the Bumiayu temples, b) to analyze water activity in Bumiayu temples c) to analyze the distribution and orientation of the Bumiayu temples. The qualitative method is used with descriptive and expansive reasoning, precisely the order using the Widyamanti classification (2016). The distribution/orientation of the temples uses data proximity analysis. The results showed that the Bumiayu temple area was lowland with an elevation of 11 masl - 20 masl and was on a rather sloping (8 % - 13 %). The landform consists of the river terrace, natural embankment, swamp. The enshrinement area consists of 4 rooms bordered by rivers and lakes. Location is in a group position and surrounded by canals that tributaries of the Lematang River. In the past, the community had managed the environment. They made canals to regulate water and transportation facilities in Bumiayu temple area. In addition, the canal also serves to fulfil practical and ritual needed.</p> <p><strong>Keywords:</strong> pattern, wet land, temple Bumiayu</p> <p>&nbsp;</p> Sondang Martini Siregar Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-02 2024-02-02 19 01 66 79 AGROBİOLOGİCAL PARAMETERS OF SOME LOCAL, AND İNTRODUCED COLLECTİBLE GRAPE VARİETİES, GROWN İN THE CONDİTİONS OF THE ABSHERON DİSTRİCT https://www.acgpublishing.com/index.php/CCB/article/view/291 <p>The article presents the results of the research work on the study of agrobiological parameters, morphological and technological characteristics of some local (Ag pishraz, Gara kechimemesi, Gara pishraz, Gara urza, Gara khatyny, Gozal uzum, Gomushimeme, Galshan, Ganja kechimemesi, Khalbasar) and introduced (Danaburnu, Dekabrskiy, Janjal kara, Dnestrovskiy rozovy, Doina, Ichkimar, Cardinal, Kuljinskiy, Moldova, Muscat Italian, Pobeda, Presentabill, Sultani, Taifi pink, Tuya tish) collectible table grape varieties grown in the conditions of the Absheron district.</p> <p>In the course of the scientific-research work, classical and modern research methods were used, such as the Mann-Whitney Wilcoxon U-criterion, the Student's t-criterion, the Pirson χ<sup>2</sup> criterion, mathematical and statistical analysis, digital description of varieties according to the international ampelographic descriptors and assessment of prospects of varieties according to the “ideal variety” innovative model, proposed by the OIV, etc.</p> <p>As a result of mathematical and statistical processing of the data obtained during the study, it was revealed that the yield indicators of the studied grape varieties Ichkimar, Muscat Italian, Pobeda, Presentabill, Taifi pink and Tuya tish significantly exceed the control variety Danaburnu. For the rest of the varieties, the difference with the control variety was insignificant.</p> <p><strong>Keywords:</strong> grapes, bunch, introduced variety, yield, quality, mathematical and statistical analysis, collection garden</p> V.S.Salimov, A.S.Huseynova, S.Ş. Abdulaliyeva, M.M. Alekberova, F.A.Aslanova Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-13 2024-03-13 19 01 283 293 ETHNOPHARMACOLOGICAL STUDY OF PLANTS, IN SUBURBAN POPULATIONS OF THE MUNICIPALITY OF CAMPECHE (MEXICO), FOR THE TREATMENT OF PARASITOSIS https://www.acgpublishing.com/index.php/CCB/article/view/462 <p>Medicinal plants are an important resource for the health of rural residents because they live in areas where infectious diseases, particularly parasitic infections, are very frequent and the lack of health services prevents effective treatment. The objective of this study was to provide an updated critical analysis of the ethnopharmacology of medicinal plants used in the treatment of parasitic diseases in the State of Campeche, Mexico. The ethnopharmacological knowledge of five communities was studied through 247 interviews with prior consent from the informants. The survey was based on a semi-structured questionnaire with simple and flexible language to collect additional information that the residents provided. It was found that in the localities studied there is still social knowledge of the use of plants in the treatment of human parasitosis but this knowledge is at risk because there is no formal dissemination and the transgenerational transmission of knowledge is being lost.</p> <p><strong>Keywords:</strong> Public Health, Herbal Medicine, Medicinal Plants.</p> Mex-Álvarez Rafael Manuel de Jesús1*,Guillen-Morales María Magali2, Garma-Quen Patricia Margarita3, Yanez-Nava David4, Chan-Martínez Roger Enrique5, May-Suárez Oscar Adrián6 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-17 2024-04-17 19 01 618 631 DIAGNOSIS OF BRAIN AND NERVE INJURIES, A COMPREHENSIVE STUDY https://www.acgpublishing.com/index.php/CCB/article/view/829 <p>Brain and nerve injuries are complex medical conditions that require accurate and timely diagnosis for appropriate treatment and management. This essay explores various methods used in the diagnosis of brain and nerve injuries. The key diagnostic tools discussed include imaging techniques such as CT scans, MRI, and PET scans, as well as neurological tests like EMG and EEG. The essay also highlights the significance of a comprehensive patient history and physical examination in the diagnostic process. Additionally, the role of new technologies such as artificial intelligence in improving diagnostic accuracy is also examined. Overall, an integrative approach combining clinical assessment with advanced diagnostic tools is essential for effective management of brain and nerve injuries.</p> <p><strong><em>Keywords: brain injuries, nerve injuries, diagnosis, imaging techniques, neurological tests, artificial intelligence</em></strong></p> Jobran Saeed Harisi, Abdulrahman Mohammad Hussein Alabdullah, Wesam Saad Saleh Alotaibi, Mohammed Saeed Bin Shahir Mohammed Ali Hommadi, Abdullah Mubarak Saad Mesfer, Ahmed Budary Ghazi Alotaibi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-23 2024-05-23 19 01 766 771 HEALTH CARE–ASSOCIATED INFECTIONS AND THE RADIOLOGY DEPARTMENT https://www.acgpublishing.com/index.php/CCB/article/view/849 <p>This essay explores the issue of Health Care–Associated Infections (HAIs) in the context of the radiology department. The essay discusses the importance of addressing HAIs in the radiology department and presents a literature review on the topic. The methodology used for this essay includes a review of relevant research articles, guidelines, and reports. The results highlight the prevalence of HAIs in the radiology department and identify key risk factors. The discussion section explores strategies for reducing the risk of HAIs in the radiology department, including infection control measures and quality improvement initiatives. The conclusion emphasizes the need for a multidisciplinary approach to addressing HAIs in the radiology department and underscores the importance of patient safety in healthcare settings.</p> Hadeel Abdulrahman Hashim, Ahmed Saud Aldalbahi, Mohammed Sulaiman Abdulkarim Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-27 2024-06-27 19 01 1013 1016 EXPLORING THE RELATIONSHIP BETWEEN INTERPROFESSIONAL TEAM CLIMATE AND JOB SATISFACTION AMONG PHYSICIANS, DENTISTS, NURSES, PHARMACISTS, RESPIRATORY THERAPISTS, AND HOSPITAL MANAGERS IN A SAUDI ARABIAN ARMED FORCES HOSPITAL https://www.acgpublishing.com/index.php/CCB/article/view/865 <p><strong>Objective:</strong>&nbsp;To explore the relationship between interprofessional team climate and job satisfaction among healthcare professionals in a Saudi Arabian military hospital.</p> <p><strong>Methods:</strong>&nbsp;A cross-sectional survey study was conducted at Hafr Al-Batin Armed Forces Hospital in Saudi Arabia. A total of 248 healthcare professionals, including physicians, dentists, nurses, pharmacists, respiratory therapists, and hospital managers, completed the Team Climate Inventory (TCI) and the Job Satisfaction Survey (JSS). Pearson correlation and multiple regression analyses were performed to assess the relationship between TCI and JSS scores.</p> <p><strong>Results:</strong>&nbsp;A significant positive correlation was found between overall TCI and JSS scores (r=0.74, p&lt;0.001). Among the TCI subscales, vision (r=0.69, p&lt;0.001), participative safety (r=0.67, p&lt;0.001), task orientation (r=0.65, p&lt;0.001) and support for innovation (r=0.61, p&lt;0.001) had significant correlations with job satisfaction. Multiple regression analysis revealed that the TCI subscales collectively explained 59.4% of the variance in job satisfaction (R&lt;sup&gt;2&lt;/sup&gt;=0.594, F(4,243)=89.38, p&lt;0.001). Vision was the strongest predictor of job satisfaction (β=0.32, p&lt;0.001), followed by participative safety (β=0.26, p&lt;0.001), task orientation (β=0.22, p&lt;0.001) and support for innovation (β=0.17, p&lt;0.01).</p> <p><strong>Conclusions:</strong>&nbsp;A positive team climate is strongly associated with higher job satisfaction among interprofessional healthcare teams in a Saudi military hospital setting. Strategies to enhance shared vision, psychological safety, commitment to excellence and support for innovation may promote job satisfaction and staff retention. Further research is needed to identify interventions to foster these team attributes.</p> Waleed Abdullah Ahmed Alzahrani, Abdulaziz Mohammed Ahmed Alghamdi, Mamdouh Ali Ibrahim Alzahrani, Mohammed Matar Muidh Alshamrani, Mansour Farhan Ayed Alhazmi, Rashed Abdullah Jazaa Alharbi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-10 2024-01-10 19 01 1156 1167 FUNGAL SECONDARY METABOLITES: EMERGING THERAPEUTIC AGENTS FOR BREAST CANCER: IN-SILICO STUDY https://www.acgpublishing.com/index.php/CCB/article/view/882 <p>Cancer is a prevalent and deadly disease that significantly impacts human health and well-being, ranking as a leading cause of death globally. Genetic variations or mutations in genes associated with breast cancer, such as BRCA1 and BRCA2, can result in the overexpression of tumor suppressor genes. Despite advancements in cancer research and medicine, the development of efficient and safe drugs for breast cancer remains a significant challenge due to the severe side effects associated with many existing treatments. Medicinal fungi have traditionally been used to treat various diseases. In this study, we aimed to investigate the effectiveness of secondary metabolites from <em>Aspergillus flavus</em> in targeting tumor suppressor proteins associated with breast cancer. We utilized an in-silico method to identify potential compounds that could act as strong inhibitors for breast cancer treatment. Molecular docking studies were conducted using compounds known to be effective against BRCA1, BRCA2, and TP53. The pharmacological profile of the secondary metabolite, including PASS, bioactivity scores, ADMET, cell line cytotoxicity, cardiac toxicity, and organ and endpoint toxicity, was comprehensively evaluated. Among the secondary metabolites analyzed, vitexin exhibited the highest binding affinity energy to BRCA1, BRCA2, and TP53 proteins, respectively. This discovery suggests that vitexin could be a promising candidate for the development of selective and potent tumor suppressor inhibitors for breast cancer treatment. This study represents an initial step towards the rational design of novel inhibitors for breast cancer therapy. By targeting tumor suppressor proteins such as TP53, BRCA1, and BRCA2, we aim to develop more effective and safer drugs for breast cancer patients.</p> Shahad S. Alsharif, Bayan H. Sajer Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-13 2024-08-13 19 01 1306 1330 BIOINSECTICIDAL ACTIVITY EVALUATION OF PERGULARIA TOMENTOSA AND URTICA DIOICA AGAINST INSECT VECTORS? MOSQUITOES AND PHLEBOTOMINE SAND FLIES https://www.acgpublishing.com/index.php/CCB/article/view/903 <p><strong>ABSTRACT</strong></p> <p>Plant extracts are showing to be a good alternative sources, instead of conventional pesticides, for pest and vector insect control agents. Plant&nbsp; extracts and essential oils were used&nbsp; as bioinsecticides&nbsp; products and&nbsp; are exhibited a toxicity to insect pests with a low effects on non target animals and environment. <em>Pergularia tomentosa&nbsp;</em>and<em>&nbsp;Urtica dioica&nbsp;</em>are plants that have been widely used in traditional medicine since ancient times due to their different medicinal properties.&nbsp;The purpose of the present study was to assess the adulticidal activities of a medicinal plant, <em>P. tomentosa&nbsp;</em>and<em>&nbsp;U. dioica&nbsp;, </em>against the most abundant insect vectors in Algeria; the domestic mosquito <em>Culex pipiens </em>and phlebotomine sand flie <em>Phlebotomus papatasi</em>, under laboratory conditions. The toxicological assays were carried out using a ethanolic extracts formulation of <em>P. tomentosa&nbsp;</em>and<em>&nbsp;U. dioica </em>separately, with different concentrations (150, 200, 300, 400 µl/ml air) on the adults of the mosquito and phlebotomine sand flies. The obtained results showed a highly significant toxic effect of these extract plants for the tested concentrations, with concentration response relation-ship mortality, for the treated adults of both insect species. &nbsp;The lethal concentrations values with confidence limits (LC50 and LC90) against mosquito, &nbsp;were estimated at &nbsp;179.9, 266 µl/ml <em>P. tomentosa&nbsp;</em>and at 216.5 and 383.8 µl/ml for <em>U. dioica&nbsp;</em>. Whereas the LC50 and LC90&nbsp; values of the bioassay against phlebotomine sand flies were higher, with 192.7 and 278 µl/ml for <em>P. tomentosa&nbsp;</em>and 184,&nbsp; 315 µl/ml&nbsp; <em>U. dioica&nbsp;. </em>It was concluded that <em>P. tomentosa&nbsp;</em>and<em>&nbsp;U. dioica&nbsp;</em> extracts exhibit an&nbsp; insecticidal effects against adult mosquito and phlebotomine sand flies<em>&nbsp; </em>and could be considered as a potential alternative to the widely used the conventional insecticides.</p> Gaouaoui Randa, Zeroual Samir, Lillia Lembrouk, Boudjelida Hamid Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-10 2024-09-10 19 01 1586 1598 THERAPEUTIC POTENTIAL OF ALOE VERA EXTRACT ON HAEMATOLOGY, HEPATOXICITY, AND NEPHROTOXICITY INDUCED BY COPPER IN LABEO ROHITA https://www.acgpublishing.com/index.php/CCB/article/view/922 <p>An experiment was conducted to find the therapeutic potential of Aloe vera extract on haematology, hepatotoxicity and nephrotoxicity induced by copper in <em>Labeo rohita</em>. Four treatments were made. T<sub>0</sub> served as the controlled treatment. Juveniles in the T<sub>1</sub> were exposed to 15 mg/L CuCl<sub>2</sub> while those in T<sub>2</sub> were exposed to 20 mg/L CuCl<sub>2</sub>. Juveniles in the T<sub>3</sub> were exposed to 25 mg/L CuCl<sub>2</sub> for 21 days. After this period all groups of fish were supplemented with 20g/kg Aloe vera extract for one week. At the end of the trial, both haematological parameters and the histopathology of the liver and kidney were analyzed. The results showed a substantial decrease in RBCs, haemoglobin (Hb) and haematocrit (HCT) values across all metal-treated groups T<sub>1</sub>, T<sub>2</sub>, and T<sub>3</sub> as compared to the control group. The control group T<sub>0 </sub>(2.05±0.05) had the greatest RBC count after receiving 0 mg/L of copper chloride. The lowest RBC count was seen in group T<sub>3</sub> (0.63±0.175). The control group T<sub>0</sub> had the greatest haemoglobin level (2.99±0.027) while the lowest amount was found in group T<sub>3 </sub>(0.70±0.53). T<sub>3</sub> group had the greatest white blood cells count (18.6±0.36) while the T<sub>0</sub> control group had the lowest (11.64±0.050). The control group T<sub>0</sub> had the highest platelet count (23.5±0.9) whereas group T<sub>3</sub> had the lowest (9.71±0.7). The haematological parameters examined included haematocrit (Hct), haemoglobin (Hb), platelets, red blood cells (RBCs), white blood cells (WBCs), mean corpuscular volume (MCV). Copper chloride-induced hepatotoxicity appeared as hepatocyte inflammation, necrosis, clumped chromatin and cytoplasmic vacuolization. For histopathological analysis kidney were stained and examined under a compound microscope to identify any structural changes or damage. Data collected from these analyses were statistically analyzed using one-way ANOVA to determine the significance of differences between the control and treated groups.</p> <p><strong>&nbsp;</strong></p> Mariam Khalid, Nimra Naseer, Dr. Amara Akhtar, Muhammad Faraz Haider, Awais Zia, Muhammad Ahmed Saqib Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-16 2024-10-16 19 01 1815 1825 TRYPANOSOMES, A BLOOD PARASITE OF RAJIDAE (ELASMOBRANCHII, RAJIFORMES) OFF THE ALGERIAN COAST. https://www.acgpublishing.com/index.php/CCB/article/view/203 <p>Trypanosomes were found from the blood of tow rajidean fishes (Raja miraletus and Raja asterias) off the central Algerian coast. We described shortly and illustrated this blood protozoan parasites, based on morphological characters. Light microscopy and Immunofluorescence were used for the observation and study of these parasites.&nbsp; Drawings were scanned and redrawn with Adobe Illustrator CS5.1. Specific characteristics such as&nbsp;&nbsp; and morphometric measurements are within the ranges given in previous description by Laveran and Mesnil 1904 of rajidean trypanosomes. Unfortunately, there is no vouchers available for comparison of rajidean Trypanosoma of the type host. Thus, as hosts are different, and localities are widely separated. This is the first record of Trypanosoma off Algerian cost.&nbsp;</p> <p><strong>KEY WORDS</strong>: -Protozoans, Parasites, Trypanosoma, Mediterranean Sea, Rajidae.</p> Sabrina Kefil 1,2*, Safia Abla 1, Chahinez Bouguerche 3, Katia Yata 1, Philippe Grellier 4, Nadia Kechemir-Issad 2. Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-12 2024-02-12 19 01 149 161 STUDY THE RELATIONSHIP BETWEEN GHRELIN LEVEL AND SOME BIOCHEMICAL MARKER IN ANBAR CITY https://www.acgpublishing.com/index.php/CCB/article/view/303 <p>The results showed that the sex of the patients in the four groups did not reveal any statistically significant differences in the averages of sex (males and females) between the two groups (controlling healthy people). The data showed that there was a significant difference between the averages of the gum disease patients, and the average age of the patients in the four groups included ranged the study ranged from 24.75 years in patients with obesity without the gum disease group to 32.55 years in patients with obesity and the gum disease group, and the data showed that ghrelin parameters varied in their effect on obesity and gum disease, which appeared in their values for the four tested groups studied. People suffering from obesity and gum disease showed the highest significant value in the level of ghrelin, as it was recorded at 189.90 mol/ml compared to 119.30 mol/ml for the control group. The results revealed that all groups of patients had a significant increase in the concentration of T3 compared to the healthy control group, and the patients also Those suffering from obesity without gum disease had a significant increase in T3 levels, which recorded 97.60 ng/dL with a standard deviation of 19.56, compared to 92.40 ng/dL with a standard deviation of 20.17 for the control group. The group of patients suffering from obesity without gum disease showed a low T4 level value, recording 6.96 micrograms/dL, while the control group recorded 7.73 micrograms/dL. The data showed that there was a significant difference in the average TSH level between the studied groups, as the TSH level in patients suffering from obesity and gum disease increased significantly, recording mIU/L with a standard deviation of 1.11 compared to 1.74 mIU/L with a standard deviation of 1.21 for the control group.</p> <p><strong>Keywords:&nbsp;&nbsp; </strong>Obesity, Ghrelin, TSH, gum disease.</p> 1 Abdulrahman Khalid Mssdf Albukhalefah **2 Şevki Adem, 3 Muhammad Hammad Jasim Alajeely, 4 Hussein Ali Nayyef Nayyef Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-26 2024-03-26 19 01 392 404 PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES OF OLIVE MILL WASTEWATER https://www.acgpublishing.com/index.php/CCB/article/view/818 <p>Olive Mill Wastewater (OMWW) is a significant environmental challenge due to its high organic matter content, particularly 1phenolic compounds, which can inhibit microorganism growth and cause pollution in surface water, soil, and ecosystems. Despite its pollution, OMWW is also a rich source of natural antioxidants, including polyphenols, which have various potential health benefits. This study focuses on the in vitro evaluation of the antibacterial and antioxidant activity of OMWW collected from traditional oil mills in Fez, Morocco, and Tizi Ouzou, Algeria. Physicochemical characterization revealed variations in pH, electrical conductivity, dry matter content, water content, ash content, organic materials, fat, suspended matter, polyphenols, and flavonoids between the two sources. Moroccan OMWW exhibited higher polyphenol content, known for its antioxidant properties. Bacteriological analyses indicated the absence of total aerobic mesophilic flora, total and fecal coliform, and <em>Staphylococcus aureus</em> in the studied OMWW, suggesting its potential antimicrobial properties attributed to its acidity and the presence of antimicrobial substances such as phenolic compounds. Moroccan and Algerian OMWW exhibited antibacterial effects against various bacterial strains, with minimum inhibitory concentrations (MIC) ranging from 3% to 14%.&nbsp; The antioxidant activity of OMWW was evaluated using 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) tests, with Moroccan OMWW demonstrating slightly stronger antiradical and reducing power activities. This research highlights the promising potential of OMWW as a natural antimicrobial and antioxidant agent, potentially serving as a valuable source of bioactive compounds with potential therapeutic applications.</p> <p><strong>Keywords:</strong> Olive mill wastewater, Antioxidant activity, Antibacterial activity, Polyphenols.</p> Fatiha Abdellah1’2,*, Khaled Hamden2, Tayeb Silarbi1’2, Laid Boukraa1, Si Mohamed Hammoudi1and Rachida Benaraba1 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-28 2024-04-28 19 01 500 518 APPLICATION DEVELOPMENT "MY BESTIE KESPRO" AS AN ANDROID-BASED ADOLESCENT REPRODUCTIVE HEALTH EDUCATION MEDIA https://www.acgpublishing.com/index.php/CCB/article/view/838 <p><strong>Introduction:</strong> Media is one of the means of learning for adolescents. Media use in health education can help clarify information with an attractive display that is easily accessible and operated and involves the five senses. The current era of digitalisation encourages public health literacy to increase, especially in adolescents close to <em>gadgets</em>, so it is known as <em>e-health literacy.</em> Namely, digital health literacy is the ability to search, find, and understand health information available in electronic resources and use information obtained from these resources to overcome health problems. <strong>Objectives:</strong> To develop the <em>My Bestie Kespro application </em>as a medium for promoting reproductive health. <strong>Method: </strong>This type of research is qualitative with an <em>exploratory case study approach. </em><strong>Research Results</strong>: The results of <em>the expert review of the My Bestie Kespro application </em>found that the average score based on the design was 4.66, with suitable criteria. The results of the end user <em>trial </em>are &gt; 80% (reaching 90%) with perfect and reasonable criteria.&nbsp; <strong>Conclusion: </strong>My Bestie Kespro application <em>media </em>is suitable to be used as a medium for reproductive health education in adolescents.</p> <p><strong><em>Keywords: Media, My Bestie Kespro, Reproductive Health, Application </em></strong></p> Muhlisa1, Ridwan Amiruddin2, Apik Indarty Moedjiono3, Suriah4, Rizal Damanik5, Ummu Salmah6, Sudirman Nasir7, Intan Sari Areni8 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-31 2024-05-31 19 01 OLEIC ACID LEVELS IN BREASTFEEDING (0-24 MONTHS) AND DETERMINANTS THAT AFFECT IT: LITERATURE REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/856 <p>This paper presents the results of a literature review on Oleic Acid Levels in Breast Milk and its Determinants. The search refers to the Preferred <em>Reporting Items for Systematic Reviews</em> (PRISMA) guidelines. The literature in this study is accessed from scientific article sites that have open access, such as Hurzing Publish or perish, with a selection of Scopus-indexed journals obtaining 200 articles, indexed Google Scholar 1154 articles, Cochrane Library 67 articles, PUBMED 97 articles, CINAHL 110 articles, MEDLINE 47 articles and after going through the article extraction process, followed by the extraction technique, The strategy used is the PICOS framework of this article then in the related further analysis title and abstract and obtained 16 eligible articles. Various forms of intervention have been carried out. To increase exclusive breastfeeding. Expanding the knowledge of mothers and families about the content of breast milk, especially oleic acid, can prevent cancer. Several articles found that providing knowledge about the content of breast milk, such as oleic acid, can increase breastfeeding exclusively.</p> Nursari Abdul Syukur,, Citrakesumasari, Anwar Mallongi, Syamsiar S.Russeng Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-17 2024-07-17 19 01 1059 1078 THE EFFECT OF CARBOXYMETHYL CHITOSAN AMORPHOUS CALCIUM PHOSPHATE APPLICATION ON PRIMARY TEETH ENAMEL HARDNESS https://www.acgpublishing.com/index.php/CCB/article/view/872 <p>Dental caries is an oral disease that often occurs in children, especially in developing countries. The importance of early caries prevention triggers many studies on new prevention methods, especially remineralizing materials. Tooth remineralization can be observed by testing the hardness of the tooth structure. To analyze the effect of CMC-ACP application on the enamel hardness of primary teeth. Experimental laboratory study. 36 primary tooth enamel samples were used; the samples were demineralized with 37% phosphoric acid etching, then divided into 3 groups, namely the negative control group with no treatment, the positive control group with CPP-ACP application, and the CMC-ACP application group. The enamel hardness test was carried out after applying the material on 7 days and 14 days using Vickers Hardness Tester. The results of the enamel hardness test on day 7 and day 14 of CMC-ACP applications were calculated using the <em>paired sample t-test</em> with a significance limit of p&lt;0.05. The results of this test p = 0.001. The results (p&lt;0.05) showed that enamel hardness values on day 7 CMC-ACP application had a statistically significant difference from the group on day 14. There was a significant increase in primary tooth enamel hardness from the application of CMC-ACP on days 7 and 14.</p> Adela Andartya, Heriandi Sutadi, Sarworini B. Budiardjo Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-05 2024-08-05 19 01 1257 1271 SEASONAL VARIATION IN COLLEMBOLAN DIVERSITY: A COMPARATIVE STUDY OF AGRICULTURAL AND FOREST ECOSYSTEMS IN WARANGAL DISTRICT, TELANGANA STATE, INDIA https://www.acgpublishing.com/index.php/CCB/article/view/891 <p>This study investigates the seasonal variation in Collembolan diversity within agricultural and forest ecosystems in Warangal District, Telangana State, India, emphasizing the impact of seasonal changes and land use practices on soil arthropod communities. The Shannon-Weiner Index was used to assess the diversity of Collembola species during Winter, Summer, and Monsoon seasons. Results indicate that both ecosystems exhibit the highest diversity in Winter, suggesting favorable conditions for Collembolan populations. However, the agricultural ecosystem shows a marked decline in diversity during Summer, attributed to extreme temperatures and intensive farming activities, which disrupt soil habitats. In contrast, the forest ecosystem maintains relatively stable diversity across seasons, with a gradual decline during the Monsoon season, likely due to the protective nature of the forest environment that buffers against environmental fluctuations. The Monsoon season prompts a partial recovery in Collembolan diversity in both ecosystems, though agricultural lands recover more slowly due to issues such as waterlogging and soil compaction. These findings are consistent with previous studies that highlight the resilience of forest ecosystems and the vulnerability of agricultural lands to seasonal extremes. The study underscores the importance of adopting sustainable agricultural practices to mitigate the adverse effects of seasonal variations on soil biodiversity, ensuring long-term ecosystem health and productivity. This research contributes to the broader understanding of how land use and seasonal dynamics influence soil arthropod diversity, offering valuable insights for the management of agro-ecosystems in semi-arid regions.</p> Lakshmi Merugu, Esam Narayana Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-21 2024-08-21 19 01 1488 1500 FROM ACCEPTANCE TO ADHERENCE: UNVEILING PATTERNS IN DIALYSIS PATIENT CARE IN THE PHILIPPINES https://www.acgpublishing.com/index.php/CCB/article/view/911 <p><strong>Abstract </strong>– The study focused on the Acceptance of the Condition and Medication Adherence of Dialysis Patients. The study utilized descriptive Correlational Design. Moreover, the study was conducted at a selected dialysis center in Cebu City, catering to a diverse dialysis patient demographic. Participants will include adult patients (aged 18 years and above) diagnosed with end-stage renal disease (ESRD), undergoing regular dialysis treatment at the selected centers. The inclusion criteria will encompass patients who have been undergoing dialysis for at least three years. Likewise, a structured questionnaire, based on validated scales like the Acceptance of Illness Scale (AIS) by Felton et al. (1984) and the Morisky Medication Adherence Scale (2008), will be used to measure the patient's acceptance of their condition and their adherence to medication regimens. The study yielded that the sickness condition is accepted to a high degree and most of the respondents have a high level of adherence. The study also found a strong, positive correlation between individuals' acceptance of their disease condition and their medication adherence.</p> Lloyd Matthew C. Derasin, Wilbert G. Panerio, Arlene G. Vecino and Johanna Kaye G. Cabatingan Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-16 2024-09-16 19 01 1674 1681 COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM) ON DYSMENORRHEA: A SYSTEMATIC REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/174 <p>Objectives: This systematic review aimed to evaluate the current evidence regarding the complementary alternative medicine on primary dysmenorrhea.</p> <p>Method: This systematic review study used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The literature search was done using Google Scholar, Pubmed, and Science Direct. Articles that met the inclusion criteria were assessed using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Checklist, including an explanation of sample size, explanation of sample methodology, calculation of response rate, findings/results measurement, explanation of the statistical analysis, confounding control, explanation of study limitations, and research ethics. Three independent reviewers participated in data extraction and assessment. Total of 20 out of 3,825 articles met the inclusion and exclusion criteria for review.</p> <p>Results:&nbsp; This review included 36 RCTs; the meta-analysis included 48 RCTs. Most studies showed a low or unclear risk of bias. The characteristic of the articles is the use of a clinical/controlled trial and quasi-experimental study design with the intervention target being the complementary alternative medicine on primary dysmenorrhea, the quality of the articles is categorized as good, and the measurement tools used are questionnaires and interviews. The cause of primary dysmenorrhea is often associated with high levels of inflammation in the endometrium. Elevated prostaglandin levels respond to the rise and fall of progesterone after ovulation. Overproduction of prostaglandins in the endometrium will result in hypercontractility and vasoconstriction of the myometrium. Vasoconstriction of the uterine blood vessels will reduce blood flow, muscle ischemia, and increase sensitivity to pain receptors, all of which cause period pain. Prostaglandin levels in adolescents with dysmenorrhea were twice as high as those without dysmenorrhea</p> <p>Conclusion: The results of this study suggest that acupuncture might reduce menstrual pain and associated symptoms more effectively compared with no treatment or NSAIDs, and the efficacy could be maintained during a short-term follow-up period.</p> <p><strong>Keywords</strong>: complementary and alternative medicine; dysmenorrhea; students</p> 1Nilam Noorma, 2Masni, 3 Andi Zulkifli, 4Andi Mardiah Tahir Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-27 2024-01-27 19 01 39 54 STRATEGY TO INCREASE THE COMPETITIVENESS OF LOCAL VEGETABLES AGAINST IMPORTED VEGETABLES IN PEKANBARU CITY, RIAU: A REVIEW OF CONSUMER LOYALTY https://www.acgpublishing.com/index.php/CCB/article/view/282 <p>One nutritional element that is crucial for good health is vegetables. The body needs a variety of nutrients, including vitamins, minerals, and fiber, which are found in vegetables. Local and imported veggies are the two categories of vegetables that are often consumed in Indonesia. Finding out what factors affect consumers' loyalty to imported and local veggies is the aim of this study. This study employs a comparative methodology and quantitative research techniques. In this study, questionnaires, observations, and literature reviews were used as data gathering methods. The SPSS software is then used to examine the data that has been gathered. The findings demonstrated that the elements most influencing consumer loyalty to local and</p> <p><strong><em>Keywords:</em></strong><em>Consumer: </em><em>Competitiveness</em><strong> , </strong><em>Local Vegetables, Imported Vegetables</em></p> Mery Berlian, Abdul Wahib Muhaimin, Nuhfil Hanani, Silvana Maulidah Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-08 2024-03-08 19 01 258 266 SOCIO-ECOLOGICAL APPROACH TO INCREASE PARTICIPATION IN PREVENTING HIV TRANSMISSION FROM MOTHER TO CHILD IN KARO REGENCY, NORTH SUMATRA https://www.acgpublishing.com/index.php/CCB/article/view/350 <p>Transmission of the HIV virus from mother to child poses a heavy burden on public health due to the high mortality rate in children, especially those who do not receive therapy in the first age of life, so efforts to end the transmission of the HIV virus from pregnant women to children are an important milestone in ending the global epidemic by the elimination target set by WHO is the incidence of new infections &lt;50/100,000 live births. The social-ecological framework takes a broad view of efforts to prevent mother-to-child transmission of HIV with a focus on various factors related to the program. This research aims to explore the participation of pregnant women, stakeholder participation and stakeholder barriers in efforts to prevent HIV transmission from mother to child. This research is qualitative research with a phenomenological study approach. In-depth interviews and FGDs were conducted with 32 informants consisting of Policy Makers at the Karo District Health Service, Health Workers, Health Cadres, Peer Support Cadres, Pregnant Women, Husbands of Pregnant Women, Community Figures and HIV Observer Organizations. Data were analyzed using Colaizzi's Method. The social-ecological approach contextualizes individual behavior using intrapersonal (e.g. knowledge, attitudes, behavior), interpersonal dimensions(social networks, social support), community (e.g. relationships between organizations/institutions), and public policy (e.g. implementation of Minister of Health regulations regarding mother-to-child HIV prevention programs) to provide a framework that describes interactions between layers so that solutions to individual problems not only found in the individual but solutions may be found in other layers where the individual lives and interacts. Creating sustainable health improvements will be most effective when all of these factors are targeted simultaneously.</p> <p><strong><em>Keywords:</em></strong><em> Social Ecology, Prevention Mother To Child Transmission (PMTCT), Community leader participation,</em></p> Bebaskita Ginting1, R. Hamdani Harahap2, SarmaNursani Lumbanraja3, FazidahAguslina Siregar4 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-19 2024-01-19 19 01 468 485 ENVIRONMENT HEALTH KNOWLEDGE OF STUDENT AT UNIVERSITY FROM DIFFERENT COUNTRIES https://www.acgpublishing.com/index.php/CCB/article/view/438 <p>The research focuses on assessing international students' understanding of environmental health in order to improve their knowledge, cognition and perceptions on environmental health issues. we use a mixed methods approach, collecting data through questionnaires and structured discussions. Participants from diverse nations and communities are selected using a diverse sampling technique to ensure inclusiveness. The study aims to identify potential knowledge gaps and growth opportunities, thereby enriching sustainability education among students. Ultimately, the research aims to raise awareness and educate students on environmental issues in order to create a cleaner, healthier future. Empowered students can be key agents of change in environmental conservation efforts. By fostering environmental literacy, students gain a stronger voice in environmental discussions. The survey assesses participants' skills, understanding, and perspectives on the natural world. He highlights the importance of internet communication and medical awareness in discussions about environmental health. A questionnaire including sections on socioeconomic background, environmental and health information, risk perceptions, health-related attitudes and behaviors was used in a longitudinal study involving students from diverse backgrounds.</p> <p><strong>Keywords:</strong> learners, health in the community, risk awareness, and opinions about hazards posed by the environment.</p> Fabrice Paulin Ketchagmen Fosso, Fidan Aslanova Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-16 2024-04-16 19 01 566 596 EFFECTIVE STRATEGIES FOR REDUCING HEALTHCARE-ASSOCIATED INFECTIONS: A COMPREHENSIVE REVIEW FOR NURSING PRACTICE" https://www.acgpublishing.com/index.php/CCB/article/view/827 <p>Healthcare-associated infections (HAIs) pose a significant challenge to patient safety and quality of care in healthcare settings worldwide. Despite advancements in infection prevention and control practices, HAIs continue to exert a substantial burden on healthcare systems, contributing to increased morbidity, mortality, and healthcare costs. Nurses, as frontline caregivers, play a pivotal role in mitigating the risk of HAIs and promoting a culture of infection prevention within healthcare settings. However, several challenges and barriers hinder the effective implementation of infection control measures, including resource constraints, time pressures, knowledge gaps, resistance to change, communication barriers, and patient factors.</p> <p>This comprehensive review explores effective strategies for reducing HAIs, with a specific focus on the role of nursing practice. Drawing upon current evidence and best practices in infection prevention and control, the paper discusses key principles, innovative approaches, challenges, and future directions in the field. Strategies for addressing obstacles to infection control implementation, such as investment in resources, ongoing education and training initiatives, fostering a culture of safety, leveraging technology, and promoting interdisciplinary teamwork, are highlighted.</p> <p>By empowering nurses with knowledge, tools, and support to enhance infection control efforts, healthcare organizations can strengthen their capacity to prevent and control HAIs, ultimately improving patient safety and quality of care. The paper concludes with a call to action for healthcare stakeholders to prioritize infection control efforts and collaborate in implementing evidence-based strategies to address this critical issue.</p> <p>This abstract provides a concise summary of the paper's focus, key findings, and recommendations, offering readers a preview of the comprehensive review on reducing HAIs through nursing practice.</p> <p><u>kevwords cover various aspects of the topic:</u></p> <p>Healthcare-associated infections (HAIs ,lnfection prevention ,Nursing practice, Patient, Hand hygiene, Personal protective equipment (PPE),safety, Environmental cleaning, Antimicrobial steward ship Interdisciplinary collaboration, Evidence-based practice,</p> <p>SurveillanceCompliance ,Education and training ,Culture of safety, Communication, Innovative approaches Resource allocation, Barrier reduction, Patient engagement</p> Saleh Jebaan Alhareth, Hanan Hassan Almaqsudi, Fatimah Ali Almarhabi, Fatimah Qassem AL-Jaidan, Afaf Abdullatif Alkhamis, Seham Abdulatif Alkhamis, Jameelah Abdulaziz s Almuhsin, Sahar Mubarak Al Hatrash Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-20 2024-02-20 19 01 746 760 ROLE OF SEASONAL CHANGES IN AFLATOXIN B1 CONTAMINATION IN COMPOUND CATTLE FEEDS IN KERALA, INDIA. https://www.acgpublishing.com/index.php/CCB/article/view/847 <p>Aflatoxin B<sub>1</sub> (AFB<sub>1</sub>) is the most toxic and primarily produced mycotoxin in Agricultural products around the globe, and its consumption causes life-threatening effects in humans and animals. Similarly, contaminated animal feeds will carry the toxin to animal products, like milk, eggs, and meat. This study discusses the role of seasonal changes in the contamination of Aflatoxin B<sub>1</sub> in three branded compound cattle feeds in Idukki, Kollam, and Palakkad districts in Kerala, India. The study revealed that the monsoon (South Western Monsoon (SWM) and North East Monsoon (NEM)) cause elevated Aflatoxin B<sub>1</sub> in the compound cattle feeds. On average, 65.28% of the total samples comply with the Bureau of Indian Standards (BIS) of AFB<sub>1</sub> (20 µgkg<sup>-1</sup>) in compound cattle feeds, while the European Commission regulation (5 µgkg<sup>-1</sup>) satisfies only 17.36%. Moreover, a significant correlation was observed between Water activity (aw) and AFB<sub>1</sub> in the compound cattle feed. The safe Water activity (a<sub>w</sub>) of more than 95% of the samples confirmed that AFB<sub>1</sub> contamination occurred in the raw materials, not the compound cattle feeds. The theoretical extrapolation of Aflatoxin M<sub>1</sub> from Aflatoxin B<sub>1</sub> content in the tested samples pointed out that the cattle feed tested did not produce beyond the limit of FDA/Codex regulation for Aflatoxin M<sub>1</sub> (0.5 µgkg<sup>-1</sup>) in the milk by the intake of compound cattle feeds maximum of 6 kg day<sup>-</sup>1 at the reported AFB1 contamination rate. This study will provide insights into AFB<sub>1</sub></p> <p>contamination throughout various seasons in compound cattle feeds in three districts in Kerala and its subsequent carryover into milk.</p> <p>Keywords: Aflatoxin, <em>Aspergillus</em>, Carcinogenicity, seasonal changes, compound cattle feeds, Water activity</p> Chammakalayil Sukumaran Arun , Dr Pambayan Ulagan Mahalingam , Dr Haris Parengal . Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-26 2024-06-26 19 01 983 1003 ANALYSIS AND EVALUATION OF GENETIC FACTORS IN THE DEVELOPMENT OF CHRONIC DISEASES. https://www.acgpublishing.com/index.php/CCB/article/view/863 <p>Genetic factors play a significant role in the development of chronic diseases, influencing an individual's susceptibility and response to various environmental factors. Understanding the interplay between genetics and chronic diseases is crucial for advancing personalized medicine and improving patient outcomes. This essay provides an analysis and evaluation of genetic factors in the development of chronic diseases, exploring the current literature and highlighting key findings. The methodology, results, and discussion sections will delve into specific genetic markers associated with common chronic diseases, such as cardiovascular disease, diabetes, and cancer. Ultimately, this essay aims to consolidate the existing knowledge on genetic factors in chronic disease development and emphasize the importance of personalized medicine in disease management.</p> Saud Saleh M Almutairi, Saeed Yousef M. Alghamdi, Raed Sulaiman Almutairi Sarah Ibrahim Alqahtani, Abdulrahman Misfer Alqahtani, Khulud Mohammed Hakami Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2023-02-25 2023-02-25 19 01 2723 2727 INVESTIGATING THE EFFECT OF NANO-METALS ON POULTRY HISTOLOGY: A REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/880 <p>Nanotechnology is a double-edged technology, given the benefits and uses of nano-metals that are common and many in the poultry industry, using them as antibacterials, antioxidants, and antifungals, and in improving immunity and fertility, as well as adding nano-mineral elements in feed and technology for transporting medicines and vaccines, however, many nano-metals may hurt the body cell and various body tissues (especially the liver, kidneys, and testicles), as high concentrations of it may cause necrosis and damage to the cells of the liver, kidneys, and testicles, which may harm the bird’s health and thus its productivity, in addition, there may be a cumulative effect of the nano-metal in some tissues, which may be transmitted to the consumer, causing health damage, which may violate global health controls and conditions, and this is what called for nano green synthesis technology and organic chickens.</p> Hashim Hadi Al-Jebory , Mohammed Khalil Ibrahim Al-Saeedi, Rasha Fajer Al-Jebory, Hala Faez Abdul-Hadi Al-Jewahery, Majeed Ajafar, I. M. A. Abd ALzahra, Mohammad A. Elsagheer, Mohamed R. Eletmany Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-13 2024-08-13 19 01 STUDY TO EVALUATE THE REMOVAL EFFICIENCY OF 2,4-D AND 2,4,5-T IN CONTAMINATED SOIL BY ZERO-VALENT IRON NANOPARTICLES https://www.acgpublishing.com/index.php/CCB/article/view/901 <p>In this study 2,4-Dichlorophenoxy-acetic acid (2,4-D) and 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) in contaminated soil were removed using zero-valence iron nanoparticle material (nZVI), which was prepared by liquid phase reduction method. The nZVI contains 50% 10-20 nm particles and about 86.38% Fe. Soil samples were taken at four sites, with 2,4-D and 2,4,5-T contents of 4.83 - 87.98 ppm and 6.25 - 148.38 ppm, respectively. The sample with the highest concentration and the sample mixed from 4 samples taken at different points were used. With the ratio of nZVI:(2,4-D and 2,4,5-T) is 1:1 (w/w), the amount of polyacrylamid (PAA) of 0.01% and pH 3.0, the removal efficiency increased with time and depended on the initial contents. After 84 day-reaction, the content of 2,4-D and 2,4,5-T decreased from 87.98 to 10.68 and from 148.38 to 29.37 ppm, respectively for highest content samples. For mixed samples, these values were respectively &nbsp;from 39.31 to 3.53 and from 67.85 to 8.48 ppm. The removal efficiency of 2,4-D and 2,4,5-T obtained over 90 and 87.5%, respectively. During the reaction process, 2,4-D and 2,4,5-T were absorbed onto the surface of nZVI, where they were decomposed into 2,4-DCP and 2,4,5-TCP, then further dechlorinated to less toxic compounds e.g. parachlorophenon, phenon and benzene. The nZVI is considered as promising material to&nbsp;remove chlorine-containing organic compounds in soil environment.</p> Duc Pham Viet, Ha Nguyen Thi, Nam Nguyen Hoang Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-08 2024-09-08 19 01 1599 1612 ADVERSE CHILDHOOD EXPERIENCE, SOCIAL SUPPORT AND RELAPSE AMONG RECOVERING RESIDENTS OF SELECTED DRUG REHABILITATION CENTERS IN CEBU PROVINCE: A MEDIATED REGRESSION ANALYSIS https://www.acgpublishing.com/index.php/CCB/article/view/920 <p>This research probes into the interplay between Adverse Childhood Experiences (ACE), risk of relapse, and social support among Cebuano recovering residents in selected drug rehabilitation centers in Cebu. The primary objective is to explore how ACE relates to relapse risk and whether social support mediates this relationship. Participants are aged 18-59 which according to the Dangerous Drugs Board with the highest number of lifetime users. A total of N-119 participated in the study. Findings reveal a significant portion of participants reported low perceived social support (50.4%), with most having high ACE scores (61.3%) and moderate to high risk of relapse (77.3%). Spearman correlation analysis showed no significant link between ACE and relapse risk. Additionally, ACE did not directly predict relapse risk or perceived social support, but higher social support levels were associated with reduced relapse risk. The study underscores the critical role of perceived social support in mitigating relapse risk among recovering individuals, despite ACE's limited direct impact. These insights inform the importance of bolstering social support networks in substance use disorder recovery programs.</p> Monteros, Raymar Luke, Yrog-irog, Ronald C. Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-15 2024-10-15 19 01 1767 1784 MICROMORPHOLOGICAL STUDY OF GLUME DIVERSITY OF CYPERACEAE IN WESTERN HIMALAYAN REGION OF PAKISTAN https://www.acgpublishing.com/index.php/CCB/article/view/200 <p>Cyperaceae is cosmopolitan in distribution and widely distributed in western Himalayan regions of Pakistan, but limited studies have been conducted on identification &amp; classification of family at both molecular and morphological perspective. In this study western Himalayan region of Pakistan were explored to collect species previously not studied and submitted to Pakistan Museum of Natural History for future use. 20 species were selected from collection and different quantitative &amp; qualitative parameters were studied. Eight micromorphological features of specimens that includes glume shape, glume length, glume width, presence or absence of arista, glume color, midrib width, midrib color and detailed surface of glume; of these specimens were observed under light microscope and scanning electron microscope.&nbsp; These species showed 12 types of glume shape and great variation in color of both glume and midrib. Similarly, length and width of glume has wide range, and two types (Narrow, Broad) of midrib were observed in this study. Arista was present in most of species and were absent in only few species. On basis of this study, it can be said that glume morphology can be great help in correct differentiation of morphological identical species that looks similar but distinct. These results can play major role in identification of said region species at morphological level.</p> Iqra Shah1,3*, Hafiz Imran Fakhar1, Muhammad Qasim Hayat1*, Muhammad Shahbaz1, Madeeha Khan1, Beenish Anjum1, Kaleem Ullah1,2, Affan Ahmed, Umme Laila1, Saleem Haider1, Ammar Ashar1, Ijaz ul haq1, Jasia Farooq1 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-09 2024-02-09 19 01 126 139 A FUTURISTICS APPROACH FOR HARNESSING GREEN ENERGY: FROM POND SCUM TO POWERHOUSE ALGAE’S JOURNEY AS BIO-FUEL https://www.acgpublishing.com/index.php/CCB/article/view/301 <p>Bio-fuel is the fuel produced over a short period from biomass, rather than by the very slow natural processes involved in forming fossil fuels, such as oil. Bio-fuel can be produced from plants, agricultural, domestic, or industrial bio-waste. Algae is the term used for a large and diverse group of eukaryotic organisms that are photosynthetic and have chlorophyll as their primary photosynthetic pigment. Algal biomass contains a very high oil fraction and can be used for bio-fuel production. Various algal strains, Botryococcus braunii, Chlorella, Dunaliella tertiolecta, Gracilaria Pleurochrysis carterae, Sargassum, and others have been found to successfully and efficiently produce *biodiesel. Mechanism of biofuel production includes transesterification and esterification of oil with alcohol. This review mainly focuses on the various algal strains isolated from various sites that are responsible for bio-fuel production, production mechanisms, and various applications of bio-fuels.</p> <p><strong>Keywords: </strong>Biomass, Fossil fuels, Photosynthetic, Chlorophyll, Biodiesel, Transesterification, Esterification</p> Shiwangi Bharti1, Varsha Gupta1, Mansvi Yadav1, Deepesh Kumar Neelam1, Devki1, Ravi Kant Rahi1* Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-26 2024-03-26 19 01 345 363 MEDULLARY THYROID CANCER: GENERAL REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/808 <p>The thyroid gland in the neck plays a crucial role in metabolism, growth, and calcium regulation. It has two lobes connected by an isthmus and is highly vascularized, receiving blood from the superior and inferior thyroid arteries. Venous drainage occurs through the superior, middle, and inferior thyroid veins, while lymphatic drainage involves nodes around the trachea and neck. Medullary thyroid cancer (MTC), originating from parafollicular C cells, accounts for 4-10% of thyroid cancers and can be sporadic or hereditary. Diagnosis includes fine-needle aspiration, calcitonin, and CEA levels, with imaging for metastasis. Treatment often involves thyroidectomy and lymph node dissection. Targeted therapies, such as RET-kinase inhibitors, are available for advanced cases. Post-surgery, monitoring serum calcitonin and CEA helps assess recurrence.</p> Ayman A. Amin, Hamdy M. Hussein, Ahmed K. Fekry, Mohamed Mubark Copyright (c) 2022 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-27 2024-10-27 19 01 1912 1929 FCATORS INFUENCING REPLASE FOLLOWING ORTHODONTIC TREATMENT.A SCOPING REVIEW. https://www.acgpublishing.com/index.php/CCB/article/view/836 <p>Orthodontic treatment results are prone to relapse over time, which is the unfavorable change in position of teeth to its original position before orthodontic treatment. Retention is an important part of almost every case of orthodontic treatment. There are many contributing factors to the incidence of a relapse. This article aims to explain the incidence and prevention of relapse after orthodontic treatment through reviewing literature published during 2000 to 2024 which discusses topics that are appropriate and related to relapse and retention. Sources were taken from textbooks, journals and websites that can be accessed through Google Scholar and PubMed databases. A total of 30 references were found, and 9 articles were included in the integrative review after further analysis. This article concludes that relapse is a common occurrence after orthodontic treatment because of gingival and periodontal factors, occlusal factors, soft tissue factors, hard tissue factors, and growth factors, and its prevention requires the use of retainers, either removable or fixed, depending on the case.</p> Sultan Hameed AlAnazi, Ahmed A Aldeaij Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-11-01 2024-11-01 19 01 1947 1954 THE IMPACTS THE ACCURACY, RELIABILITY, AND CREDIBILITY OF LABORATORY TEST RESULTS. https://www.acgpublishing.com/index.php/CCB/article/view/854 <p>Laboratory test results play a crucial role in the field of science and medicine, providing valuable information that guides diagnosis, treatment, and research. However, the accuracy, reliability, and credibility of these results are essential to ensure the validity of conclusions drawn from them. This essay explores the impacts of accuracy, reliability, and credibility on laboratory test results, highlighting the factors that influence these qualities and the potential consequences of errors. By understanding the importance of these factors, professionals can work towards improving the overall quality of laboratory testing practices.</p> Yasir Awad Ahmed, Areej Nasser Saud Alrami Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-15 2024-07-15 19 01 1040 1043 EXPLORING THE ROLE OF OXYTOCIN IN ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD): A LITERATURE REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/870 <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; In addition to significant social difficulties, attention deficit hyperactivity disorder (ADHD) is a common mental illness characterized by impulsivity, hyperactivity, and inattention. Pharmacological interventions, the mainstay of traditional treatments, can have serious side effects and adverse consequences. Moreover, recent research has started to investigate another potential treatment for regulating ADHD. Oxytocin is known for its function in social cognition, behavior, emotional control, stress reduction, and social bonding. A few studies directly connected the oxytocin levels and OXTR gene variants with ADHD symptom control particularly in humans. This review summarizes current research and emphasizes the special potential of oxytocin as a target for ADHD treatment. By highlighting the need for more targeted research to confirm the benefits of oxytocin, new therapeutic avenues that may be less harmful than currently prescribed drugs become accessible.</p> Rahiq A. Alyahya, Mohamed O. Mohamed , Batool A. Alkhalifah , Sarah S. AlKhaldi , Amany M shehata, Sokara Ali, Mohamed R. Eletmany Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-05 2024-08-05 19 01 1229 1246 WHISPERS OF LOSS: FILIPINO MOTHERS' UNTOLD JOURNEYS THROUGH INFANT GRIEF https://www.acgpublishing.com/index.php/CCB/article/view/889 <p><strong>&nbsp; </strong><em>The study focused on the Lived experiences of Filipino bereaved mothers after infant deaths. The study made use of phenomenological research design.</em> <em>Moreover, a purposive sampling strategy was utilized to select participants who have experienced the loss of an infant within the past three years.</em> <em>Likewise, Data was collected through semi-structured interviews, which offered the flexibility to explore various aspects of the participants' experiences while ensuring consistency across interviews. Furthermore, the study yielded six themes: (1) Illusion of Normalcy, (2) Fierce Storm Within, (3) Seeking Meaning Amidst Sorrow, (4) The Weight of Shadows, (5) Finding Harmony in Chaos and (6)</em> <em>Finding Light in the Darkness.&nbsp; Moreover, The study highlights the struggle between societal expectations and inner turmoil faced by bereaved mothers, emphasizing the importance of personalized assistance and empathy. It highlights the need for a more comprehensive approach to addressing loss and trauma in mothers, as societal norms often overlook their emotions and difficulties.</em></p> Jason R. Lim, Jeanette P. Lim, Jonah M. Novo Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-21 2024-08-21 19 01 1470 1478 A TRANSCENDENTAL PHENOMENOLOGICAL STUDY OF THE MOTIVATIONS DRIVING FILIPINO LIBRARIANS TO WORK ABROAD https://www.acgpublishing.com/index.php/CCB/article/view/909 <p><strong>This transcendental phenomenological study explores the motivations driving Filipino librarians to pursue careers abroad. The research addresses a critical gap in existing literature by providing an in-depth examination of the personal and professional factors that influence these individuals' decisions to work internationally. Employing Moustakas' (1994) transcendental phenomenological approach, the study gathered data from Filipino librarians employed in various countries, including the United Arab Emirates, Saudi Arabia, Bahrain, and Hungary. Semi-structured interviews were conducted and analyzed using NVivo, focusing on key themes such as career stagnation, personal aspirations, professional opportunities, and cultural adaptation. The findings reveal that motivations are deeply rooted in a combination of personal ambitions, professional growth, and the pursuit of financial stability. Moreover, the research underscores the significance of cultural adaptability and continuous learning in achieving success in international librarianship. The study contributes to the understanding of how international experiences enhance librarians' competencies and suggest implications for policy and practice in supporting the professional integration of librarians in global contexts.</strong></p> Jolo Van Clyde S. Abatayo Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-16 2024-09-16 19 01 1659 1667 ISOLATION AND PARTIAL PURIFICATION OF CYCLOOXYGENASE-2 FROM BLADDER CANCER PATIENTS AND ESTIMATION OF ITS MOLECULAR WEIGHT https://www.acgpublishing.com/index.php/CCB/article/view/170 <p>The study was carried out in the city of Mosul during the period 3/1/2022 until 6/1/2023 and included 75 people with bladder cancer, 68 males and 7 females, whose ages ranged between 50-80 years. The study included the isolation and purification of the cyclooxygenase-2 enzyme from blood serum. Patients with bladder cancer and studying its characteristics using techniques of salt displacement, membrane sorting, and ion exchange chromatography, and estimating its approximate molecular weight by electromigration technique. The study was carried out in the laboratories of the College of Science/University of Mosul. The results showed the presence of one distinct peak for the protein solution, and the purification process was relatively effective, with recovery of more than 50.82% of the enzyme activity. The approximate molecular weight was estimated using the electrophoretic migration technique, as a distinctive protein band was found that was used in estimating the approximate molecular weight of the enzyme, which is equal to (72). ) kilodaltons, and the optimal conditions for measuring enzyme activity were 5 minutes for reaction time, 7.5 for pH, temperature of 40°C, and 0.6 mM concentration of the substrate.</p> <p>Keywords: bladder cancer, cyclooxygenase-2, salt displacement precipitation, membrane sorting, ion exchange chromatography, electromigration technique</p> Mohammed Hussin Mousa1, Mohammed Bahry Hasan2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-21 2024-01-21 19 01 THE EFFECT OF COMPLETE FEED SUBSTITUTION WITH COFFEE PEEL WASTE ON THE PERFORMANCE OF THE FINISHER PHASE PIGS https://www.acgpublishing.com/index.php/CCB/article/view/280 <p>The primary objective of this research was to assess the impact of incorporating coffee husk waste as a complete feed replacement ingredient on pig performance. A total of 36 crossbred pigs, originating from Sterbyderby and Kirk, Topper and Exotic, and Abraham and Kirk, were subjected to a comprehensive study employing a 4-treatment, 3-repetition design. The analysis of variance (ANOVA) revealed that the inclusion of coffee husk waste as a partial substitute for the ration, alongside various treatment methods such as sun-dried, soaked, and boiled coffee husks, exhibited no statistically significant differences (P&gt;0.05) in ration consumption.</p> <p>However, the study did unveil significant differences (P&lt;0.01) in body weight gain and ration efficiency (P&lt;0,05) at the coffee skin substitution level. In contrast, The specific treatment of coffee skin had no significant impact on both body weight gain and ration efficiency (P&gt;0.05), and the interaction between the two factors also did not yield significant differences (P&gt;0.05).</p> <p>In summary, this study affirms the potential of coffee skins as a substitute feed ingredient in select pig rations, with the most promising outcomes observed at a 5% substitution level with boiled treatment.</p> <p><strong>Keywords:</strong> Substitution, Coffee Peel, Pig farming</p> Mien T.H Lapian, Petrus R.R.I Montong. Hapry F.N.Lapian Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-08 2024-03-08 19 01 236 242 ETHNOPHARMACOLOGICAL STUDY OF PLANTS, IN SUBURBAN POPULATIONS OF THE MUNICIPALITY OF CAMPECHE (MEXICO), FOR THE TREATMENT OF PARASITOSIS. https://www.acgpublishing.com/index.php/CCB/article/view/311 <p>Medicinal plants are an important resource for the health of rural residents because they live in areas where infectious diseases, particularly parasitic infections, are very frequent and the lack of health services prevents effective treatment. The objective of this study was to provide an updated critical analysis of the ethnopharmacology of medicinal plants used in the treatment of parasitic diseases in the State of Campeche, Mexico. The ethnopharmacological knowledge of five communities was studied through 247 interviews with prior consent from the informants. The survey was based on a semi-structured questionnaire with simple and flexible language to collect additional information that the residents provided. It was found that in the localities studied there is still social knowledge of the use of plants in the treatment of human parasitosis but this knowledge is at risk because there is no formal dissemination and the transgenerational transmission of knowledge is being lost.</p> <p><strong>Keywords:</strong> Public Health, Herbal Medicine, Medicinal Plants.</p> Mex-Álvarez Rafael Manuel de Jesús1*,Guillen-Morales María Magali2, Garma-Quen Patricia Margarita3, Yanez-Nava David4, Chan-Martínez Roger Enrique5, May-Suárez Oscar Adrián6 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-04 2024-04-04 19 01 443 456 USE OF LAB-GROWN ORGANOIDS IN DISEASE MODELING https://www.acgpublishing.com/index.php/CCB/article/view/436 <p>Ensuring accurate and dependable test findings is of utmost importance in clinical labs, making quality improvement essential. Given the growing recognition of the possible negative impact of mistakes in laboratory procedures on patient results, it is crucial to underline the ongoing need for enhancing laboratory services. A systematic literature review was performed on PubMed and the Web of Science Core Collection from October to February 2021 to assess the scientific rigor of medical laboratory quality enhancement studies. Only peer-reviewed articles published in English that satisfied the criteria for quality improvement were considered. Data extraction was performed using a standardized template, and the publications were evaluated using the Quality Improvement Minimum Quality Criteria Set (QI-MQCS) on a scale ranging from 0 to 16. Of the total 776 papers, 726 were assessed for the examination of quality in clinical laboratory literature. The studies were examined based on quality enhancement and monitoring methodologies and interventions, including education, training, task power, and monitoring. The findings revealed that the average rating of QI-MQCS for quality development articles published between 1981 and 2000 was 2.5. In contrast, for papers published between 2001 and 2020, the mean score was 6.8. This suggests a consistent and significant enhancement in quality within the clinical laboratory field. Nevertheless, there is an opportunity to develop a comprehensive framework for evaluating the quality of medical laboratory research and enhancing accreditation initiatives in the field.</p> <p><strong>Keywords:</strong> performance assessment, laboratory quality, comprehensive quality management, QI-MQCS</p> Ali Yahya Mater , Mohammed Ali Majari , Mohammed Ali Mohammed Anbari , Hassan Mohammed Ghabesh Ayashi , Afnan Mohammed Kulip Ali , Abdulqader Ali Ahmed Muthaffar ,Yahia Othman Ahmed Ghaish , Mohammed Awadh Almutairi , Walaa Abdulwahed Khalid , Nouf Abdulqader Hassan , Mohammed Amer Asiri , Jameel Abdulrahman Alnemari , Fayez Saleem Aldhaferi , Maha Mohammed Moteq Almotairi , Fawaz Awad Zaben Alenazi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-16 2024-04-16 19 01 537 544 IN VIVO AND IN VITRO TOXICITY EVALUATION OF IRON FROM RED SEA FISH PRODUCTS AND THE INFLUENCE OF OXIDATIVE STRESS: A POTENTIAL RISK TO HUMAN HEALTH. https://www.acgpublishing.com/index.php/CCB/article/view/825 <p>Fish species from the Red Sea constitute an excellent food source but are also unsafe to consume because their content of iron (Fe) is greater than the recommended level. We looked into the safety issues connected to the ingestion of iron-rich fish. Fe(II) and Fe(III) were administered to Wistar rats at a dose of approximately 200 mg/kg body weight.Hepatic cell lines (WRL-68, HepG2 and FTO2B) were subjected to iron for cytotoxicity tests.After that, H2O2 was added as a pretreatment to FTO2B cells in order to mimic oxidative stress.The <em>in vivo</em> findings demonstrated that only the Fe2+ treatment altered significantly (P &lt; 0.05) aminotransferase activity relative to the control and increased antioxidant enzyme activity and malondialdehyde (MDA) concentration. The cell lines did not exhibit toxicity from iron, which is commonly found in Red Sea fish, according to the in vitro results.On the other hand, the detrimental effects of H2O2 on FTO2B cells were enhanced by the addition of Fe(III).Additionally, the data showed that superoxide dismutase gene expression was elevated (P &lt; 0.05) following exposure to Fe(III). The data obtained indicates that consuming fish products from the Red Sea may provide a potential risk of toxicity.</p> <p><strong><em>Keywords</em></strong><em>:</em><em>Fish; Food quality; Iron; Cytotoxicity; Oxidative stress </em></p> Saber Abdelkader Saïdi1, 2 *, Othman Ahmed AlGhamdi1and Josvan Pelt3 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-10 2024-05-10 19 01 714 731 DETERMINATION OF WATER QUALITY PARAMETERS OF KELO RIVER https://www.acgpublishing.com/index.php/CCB/article/view/845 <p>Water is a wonderful gift of nature to mankind. It has its own unique properties. It is also known as universal solvent. It is essential for all living beings. Chemically water is consisting of two part of hydrogen and one part of oxygen. Its weight is 18 .The natural water is combination of following – (1)H<sub>2</sub><sup>17</sup>O, (2) H<sub>2</sub><sup>18</sup>O (3)HD<sup>16</sup>O (4) H<sub>2</sub><sup>16</sup>O (5)HD<sup>17</sup>O(6)HD<sup>18</sup>O (7) D<sub>2</sub><sup>18</sup>O(8) D<sub>2</sub><sup>17</sup>O(9) D<sub>2</sub><sup>16</sup>O.&nbsp; Because both hydrogen and oxygen have isotope, so there nine combinations is possible.<sup>1</sup> depending upon the combination of those component the properties of water vary from place to place. For example density of water varies from source to source at 4<sup>0</sup>C.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Type of Water&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Density at 4<sup>0</sup>C</p> <ul> <li>Rain Water 9999990</li> <li>Snow Water 9999977</li> <li>Ocean Water 0000015</li> <li>Water of crystallization in various minerals 0000024</li> <li>Water of plants 0000017</li> <li>River Water 0000000&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</li> </ul> <p>Water is used for several purposes. Without water life is impossible in universe. Water is found in three different forms-solid, liquid and vapors. Our planet is known as blue planet as most of the part is covered with water, but we still face crises, becoz 97% total surface water is marine water, only 3% of it is fresh water which includes glacier also. River is one of major source of surface water. River water can be used for different purpose like drinking, irrigation, domestic use, in industry and many more. If we want to use water for any one of these purpose, we first check the water quality. Water quality is measured by various parameters. WQI is used for this purpose. On the basis of water quality parameters the degree of pollution is measured. It is also necessary to calculate parameters before using water at any purpose. In our present study we discuss the water quality parameters of Kelo River in Pree Monsoon, Monsoon &amp; Post Monsoon. session. In present work I discuss some of them. In this study I choose kelo river water from seven different spots and analyze water quality parameters. Water is polluted by different reasons. Anthropogenic activity, Industrialization, Cultivation, Use of pesticide and fertilizers, Domestic waste, Sewage, irrigation, municipal waste etc. are responsible for aquatic pollution. Water quality parameters tell us whether the water is suitable for the purpose in which we want to use water. And it also tells us the level of pollution.</p> <p>&nbsp;</p> <p>KEY WORD- Aquatic pollution, WQI, Anthropogenic activity, Water pollution, Kelo River, domestic waste, Raigarh,</p> Reenu Mishra, P.K.Sing, M.M.Vaishnav, Kavita Patel Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-12 2024-06-12 19 01 957 969 IMPROVING MECHANICAL AND THERMAL PROPERTIES FOR UNSATURATED POLYESTER RESIN BY ADDING GYPSUM https://www.acgpublishing.com/index.php/CCB/article/view/861 <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This research aims to prepare polymeric composites of unsaturated polyester as a base material for gypsum. Then, their mechanical properties were studied by measuring (hardness, compressive strength, impact resistance, modulus of elasticity). To achieve this goal, samples with different weight percentages of gypsum were prepared, and the addition percentage was from (5%-50%). The study showed an increase in the properties. Mechanical increase in the percentage of reinforcement, and the best percentage was at 30%, and the addition was done at different temperatures (8, 25, 50)°C. After comparing unsaturated polyester before and after reinforcement of the prepared compounds, it was found that there was an increase in all mechanical properties after reinforcement with gypsum at (8,25,50)°C, except for the modulus of elasticity, which decreased at all temperatures. It was also found that the thermal conductivity decreased at temperatures (8, 25, and 50)°C, which indicates that polymeric compounds consisting of unsaturated polyester resins reinforced with gypsum are good thermal insulators.</p> Angham Elias Abdul Muhsen, Prof. Dr. Ebtahag Z. Sulyman Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-22 2024-07-22 19 01 1123 1143 DEVICES THAT ENABLED REMOTE MONITORING OF PATIENTS' HEALTH CONDITIONS WERE BECOMING MORE SOPHISTICATED https://www.acgpublishing.com/index.php/CCB/article/view/878 <p>The development of devices for remote patient monitoring has been steadily advancing, allowing for more sophisticated monitoring of patients' health conditions. This essay explores the evolution of remote monitoring devices, the methodologies used in this field, as well as the results and implications of this technology. Through a comprehensive analysis of the current landscape of remote patient monitoring devices, this essay seeks to shed light on the potential benefits and challenges associated with these technologies.</p> Khalid Fahad Al Harbi, Mustafa Abdulrahman Sahal Alotaibi, Defallah Hamoud Almutairi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-13 2024-08-13 19 01 STAYING ON TRACK: COMPLIANCE LEVELS AMONG ADULTS WITH DIABETES MELLITUS IN THE PHILIPPINES https://www.acgpublishing.com/index.php/CCB/article/view/899 <p><strong>Abstract</strong>: <em>the study focused on Determining the compliance to treatment of Diabetes Mellitus patients. The study employed a normative descriptive research design. To gather the necessary data, a self-constructed questionnaire was developed, specifically tailored to describe the demographic and clinical characteristics of the adult diabetic population under study. To ensure the reliability and generalizability of the study results, the researcher employed simple random sampling in selecting the study participants. A total of 200 adult diabetic respondents were chosen from five clinics, ensuring a diverse and representative sample. The study highlights that compliance rates among diabetic respondents are influenced by various socio-demographic factors. While factors like age, gender, civil status, and the length of time diagnosed or on medication were found to have no significant impact on compliance, the study underscores the importance of understanding how education and income levels can affect medication adherence. Moreover, The study recommends adopting intervention strategies to improve compliance rates among diabetic patients. These strategies should consider not only socio-demographic factors but also the psycho-social and cultural aspects of patient care</em></p> Grace C. Arcamo, Jonah M. Novo, and Naomi Datoy-Remolador Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-29 2024-08-29 19 01 1545 1559 EVALUATION OF THE EFFECTS OF ZINC APPLICATION METHODS ON TRITICUM AESTIVUM L. YIELD AND GRAIN QUALITY UNDER CHROMIUM STRESS https://www.acgpublishing.com/index.php/CCB/article/view/916 <p>Zinc (Zn) malnutrition is widespread in developing countries where cereal grains are used as staple food. Zn efficient wheat genotypes have been developed to minimize Zn malnutrition; however, there is another threat of accumulation of heavy metals in grains from heavy metal contaminated soils which would contaminate the food chain. Present study was conducted to check the impact of different Zn application methods on growth, yield and accumulation of Zn and chromium (Cr) in grains of a Zn efficient wheat cultivar grown under Cr contamination. The experiment was comprised of two factors including three contamination levels of Cr (0 ppm, 5 ppm, 15 ppm) and three Zn application methods (seed coating, soil application and foliar spray). Akbar-19 was used in this experiment which is a recent Zn efficient wheat cultivar developed for improving Zn concentration in grains of wheat. Observations including plant height, shoot length, shoot fresh weight and dry weight, spike length, 100 grains weight, photosynthetic efficiency, relative water content were recorded. Results showed that due to Cr stress, growth parameters, biological yield, photosynthetic yield and yield of wheat cultivar reduced at higher Cr level, i.e, 15 ppm. It was observed that application of Zn through seed coating, soil application and foliar spray significantly ameliorates the toxicity of Cr. Overall seed coating, foliar spray and soil application of Zn improved all parameters but grain Zn content was significantly increased through foliar spray. Soil application was also effective and play mitigative role in the presence of Cr toxicity.</p> Rimsha Ishtiaq, Muhammad Waqas, Memoona Aziz, Hafsa Farooq, Javeria Muhammad Ahmad, Mehreen Hassan, Khazeema Khan, Muhammad Hafeez Ul Haq, Muhammad Taqqi Abbas Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-07 2024-10-07 19 01 1955 1972 FORMULATON AND EVALUATION OF SOLID LIPID NANOPARTICLES CONTAINING DOXORUBICIN AND CURCUMIN-PREFORMULATION STUDIES AND ACTIVITY https://www.acgpublishing.com/index.php/CCB/article/view/196 <p>Many controlled delivery strategies have been developed in recent years in an effort to increase the solubility, stability, and bioavailability of medications that are poorly absorbed. Lipid nanoparticles have particularly intriguing qualities when it comes to delivering drugs or genes. These systems, made up of lipids stabilized with surfactants. A flexible drug delivery method called solid lipid nanoparticles (SLNs) has been formulated with homogenization process and formulation was optimized .This work aimed to synthesize solid lipid nanoparticles containing curcumin and doxorubicin. Results were found satisfactory from the preformulation examination consisting of solubility studies, particle size and LOD with no incompatibility issues with the excipients. Entrapment of both drugs in SLNs have increased the pharmacological activity compare to that available in crude drug form. In-vitro release kinetics shows sustained release with initial burst effect. The linearity was established in the concentration of 0.2- 10μg/ml for curcumin and 0.015 - 62.50µg/mL for doxurubicin.</p> <p><strong>Keywords:</strong> Chemotheraphy, Chromatogram,Solid lipid Nanoparticles,Doxorubicin, Anticancer agent, Curcumin</p> Rahul Singh,Vikrant Verma, Aadesh Kumar, Nidhi Dhama Copyright (c) 2023 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-05 2024-02-05 19 01 96 110 A COMPARATIVE ANATOMICAL STUDY OF THE LOWER EPIDERMIS OF LEAVES OF THE GENUS AEGILOPS https://www.acgpublishing.com/index.php/CCB/article/view/294 <p>In this paper leaf structure of Six Iraqi species of<em> Aegilops</em> L. have been anatomically examined. It was observed that the anatomical characters have high variation in the length of long cells in both stomatal and non- stomatal rows, length and number of stomata in microscopic field, the number of short cells, indumentum properties such as type of prickle hairs and macro- hairs, the blade and keel outline, the shape of abaxial and adaxial sclerenchyma, and bulliform cells arrangement, Finally the study show that anatomical characteristics of the leaf blade vary between studied taxa.</p> <p><strong>Key</strong> <strong>words</strong>: Anatomy,<em> Aegilops</em>&nbsp; , Poaceae, Variation</p> Hijran Mohammed Obaid Al- Dulaimi, Ruqayah Manoon Hasan Alnomani Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-19 2024-03-19 19 01 322 333 CURRENT APPLICATIONS OF LASER IN CONSERVATIVE DENTISTRY AND ENDODONTICS. A SCOPING REVIEW. https://www.acgpublishing.com/index.php/CCB/article/view/710 <p>The use of lasers is considered an innovative method for clinical use in dentistry. Recently, multiple studies have been undertaken regarding the possible applications of laser therapy in dentistry. Furthermore, owing to their ablation, penetrability, and disinfection properties, lasers have excelled in conservative and endodontic procedures, encompassing root canal therapy, vital pulp therapy (pulp capping and pulpotomy), treatment of dentinal hypersensitivity, and management of dental pain associated with pulp and periradicular diseases. This study highlights the advantages of laser-assisted pulp therapy through summarized clinically controlled trials and histological investigations. Furthermore, the innovative application of lasers to enhance root development and facilitate the removal of foreign objects (such as fractured files and fiber posts) in canals has rapidly emerged as a leading trend in contemporary research. This review provides a synthesis and analysis of the existing literature on all the previously stated laser applications. Additionally, the attributes of laser devices, such as erbium lasers, neodymium-doped lasers, CO2 lasers, and diode lasers, are elucidated and examined here, offering valuable references for laser utilization in endodontics. We also concentrate on the various wavelengths pertaining to the lasers utilized in endodontics. High-power lasers function effectively as surgical tools; moreover, low-level lasers facilitate the modulation of pulp inflammation and enhance pulp healing. This narrative review summarizes the expanded applications of lasers alongside various devices in endodontics and seeks to inspire creative ideas on the use of lasers for treating dental disorders, particularly pulp diseases, in the future.</p> Omar Ahmed Ghulam, Mousa Sulaiman Hazazi, Khalid Atif Sindi, Hasan Ahmad Taher, Ahmed Salah Alahmadi, Saleem Issam Albaradie, Somayah Sanad Al Rowaithi, Suhael Ahmed Copyright (c) 2022 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-21 2024-10-21 19 01 1835 1851 ENHANCING PROBIOTIC AND VITAMIN E SUPPLEMENTATION TO OPTIMIZE GROWTH POTENTIAL IN BROILER CHICKS https://www.acgpublishing.com/index.php/CCB/article/view/833 <p>Consumption of broilers is very high worldwide because broilers are source of protein. Many countries have restricted use of antibiotics for birds and are using probiotics as an alternative source of antibiotics. Probiotics are living microbes which increase immunity and boost growth of birds and other animals Vitamins are among essential nutrients including vitamin E. The research conducted on broiler chicks aimed to evaluate the impact of vitamin E supplementation and probiotics on growth performance and body composition. A total of 21 broiler chicks were divided into three treatment groups. Treatment 1 received a control diet, Treatment 2 was given Protexin probiotics (500 mg/Live), and Treatment 3 received both Protexin probiotics and vitamin E supplement (180 mg/kg). The study spanned 40 days, with weekly measurements taken for parameters such as body weight, weight gain, feed intake, feed conversion ratio (FCR), and specific growth rate (SGR). Analysis of body composition was conducted using various methods. Results indicated that Treatment 3 exhibited the highest significant weight gain, followed by Treatment 2 and then Treatment 1. Treatment 1 had the highest FCR value, while Treatment 3 showed the lowest. Feed intake and SGR were significantly higher in Treatment 3 compared to Treatment 1. Treatment 3 also displayed higher levels of crude protein and ash content compared to Treatment 1. Conversely, Treatment 1 had higher values of crude fat and moisture content compared to Treatment 3. The findings suggest that the combination of vitamin E supplement and Protexin probiotics can effectively enhance the growth performance of broiler chicks. This research contributes valuable insights into optimizing the economic efficiency of broiler production.</p> Dr. Amara Akhtar, Rasheeka Rasheed, Rohma Talha, Nimra Naseer, Muhammad Munawar Ramzan Naila Altaf, Noor Fatima, Irsa Saleem, Saneela Kauser, Muhammad Ahmed Saqib Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-27 2024-05-27 19 01 NEEDLE EXCHANGE PROGRAMS TO REDUCE THE SPREAD OF HEPATITIS C. https://www.acgpublishing.com/index.php/CCB/article/view/852 <p>Needle exchange programs have been implemented as a harm reduction strategy to reduce the spread of blood-borne infections, such as hepatitis C, among injection drug users. This essay explores the effectiveness of needle exchange programs in reducing the transmission of hepatitis C. Through a review of the literature and analysis of relevant research studies, it will be demonstrated that needle exchange programs play a crucial role in preventing the spread of hepatitis C among at-risk populations. The methodology involves a comprehensive search of academic databases and reputable journals to gather evidence supporting the positive impact of needle exchange programs. The discussion will focus on the key findings of the research, highlighting the benefits of needle exchange programs in reducing the incidence of hepatitis C and improving public health outcomes. In conclusion, the essay will assert that needle exchange programs are a valuable tool in combating the spread of hepatitis C and should be supported as part of a comprehensive public health strategy.</p> Seham Fayadh Eid Alanazi, Registered Nurse Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-20 2024-02-20 19 01 1032 1035 IMPLEMENTATION OF A PHYTOECOLOGICAL DATABASE FOR NORTHERN ALGERIAN SPECIES https://www.acgpublishing.com/index.php/CCB/article/view/868 <p>The Algerian Northern area is very biodiverse. It is one of the richest Mediterranean hotspot countries in terms of species, most of which are considered rare to extremely rare. It totals nearly half of Algerian flora threatened with disappearance and presents many endemics. Unfortunately, the continental natural ecosystems face various threats. Studies involving assessing biodiversity through inventories and systematic surveys to better understand these natural environments still need improvement. Because of its interest as a synthetic tool to store and manage data, an ecological Northern Algerian flora database was conceived using access, a relational database management system. Built around four tables, it allows for several queries about the floristic and ecological characteristics of about 1699 Phyto-ecological surveys. Each species is identified by a code and is characterised by several qualitative traits relating to abundance, plant formation, climatic and bioclimatic conditions, topography, and biogeographical distribution. For better exploitation of the database, “MapInfo” software, which is a Geographic Information System (GIS), has been used to map the results of queries. The produced maps reveal significant changes in the distribution of biogeographical ranges of species.</p> Naïma Baali Cherif, Nora Radi, Naïma Abila-Amalou Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-02 2024-08-02 19 01 1204 1213 FIRE INTENSITY EFFECTS ON BIODIVERSITY PATTERNS OF PLANTS IN MEDITERRANEAN WOODLANDS IN NORTHERN ALGERIA https://www.acgpublishing.com/index.php/CCB/article/view/886 <p>Algeria, like several Mediterranean countries, was exposed to devastating wildfires. These fires are a key disturbance affecting plant biodiversity patterns and evolution, causing significant threats to lives, property and economic activity in the country. The Kabylia region, in particular, through the last few years, has undergone tragic consequences due to wildfires. In context, we assessed the recovery of floristic biodiversity and the soil-vegetation relationship, in order to evaluate the fire impact on this ecosystem. A qualitative inventory of plant species and a physico-chemical analyzes were carried out in the stations of Sidi Ali Bounab; considered as a reference site (A), since it was preserved from fires and the devastated Ikhelidjen site (B), with a big fire, in the Kabylia region (Northern Algeria). the survey was carriedout, during the spring (April- June) of the year 2022 and 2023, after 2021 big fires. The flora inventory, in Sidi Ali Bounab not burned site (A), revealed the presence of 55 species are belonging to 4 classes (Magnoliopsida, Equisetopsida, Liliopsida and Polypodiopsida) and to 50 genera, 31 botanical families, 25 orders, with the Asteraeae family dominance. At the same time, the flora survey in Ikhlidjen burned area revealed a total richness of 49 species belonging to 3 classes (Magnoliopsida, Liliopsida and Equisetopsida) spread over 43 genera, 20 families, and 19 orders. The flora regeneration was observed within the Asteraceae and Fabaceae families in a soil which presents a low alkaline and high organic matter content. The analyzes of the chemical properties, from both sites (A&amp;B), showed that the quality of the soil favorized &nbsp;the installation and the diversification of the flora based on their loamy-sandy texture rich in organic, especially in the burned station and their pH as well as their electrical conductivity, which was confirmed by the ecological indices analyzes.</p> Lillia Lembrouk, Ramdane Ramdini, Hamid Boudjelida Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-19 2024-01-19 19 01 1450 1465 LEVELS OF COMPASSION FATIGUE AND ITS RELATION TO PSYCHOLOGICAL DISTRESS AMONG HELPING PROFESSIONALS https://www.acgpublishing.com/index.php/CCB/article/view/907 <p><strong>Abstract </strong>- <em>The job of helping professionals is emotionally and physically demanding by nature. They are more likely to experience the negative impacts of helping, such as compassion fatigue and psychological distress. The research study analyzed the demographic profile of 100 helping professionals from the selected institutions within Cebu City. Demographics include sex, age, job, and length of service of the helping professional. The levels of compassion fatigue and psychological distress were also assessed. Finally, the study investigated the relationship between demographic profile, compassion fatigue, and psychological distress. A quantitative study was used, and the researchers utilized a descriptive correlational survey research design to describe the relationship between compassion fatigue and psychological distress. The study used the Quota sampling method to collect data from 100 helping professionals in selected institutions from Cebu City. The study's results have shown a significant relationship between CF and PD with a correlation coefficient of ρ = 0.760 and p-value of 0.000, indicating a strong positive relationship between the two variables. However, based on the results, the correlation between CF and demographic profile was insignificant, indicating that age, sex, length of service, and specific helping profession don't influence a helping professional's risk of experiencing CF. The same was found true between PD and demographic profiles, indicating that the respondent's demographic profile does not affect their level of psychological distress. At the end of the study, the researchers proposed a program to support helping professionals<strong>.</strong></em></p> adminojs adminojs Mary Scarlette G. Auguis, Angie Ayne R. Gako, Cathlene Kate P. Abayata, Fritzie Ann N. Bartolabac, Shamen G. Sanico, and Ronald C. Yrog-Irog Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-12 2024-09-12 19 01 1641 1652 OVERUSE OF ANTIBIOTICS IN DENTISTRY. A CRITICAL REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/228 <p>Antimicrobial resistance (AMR) has been on the rise worldwide because of excessive and inappropriate use of antibiotics in healthcare. Dentists account for 10% of all antibiotic prescriptions, primarily used to treat oral infections and prevent postsurgical problems. Recent research and clinical assessments emphasize new therapy strategies that involve decreasing antibiotic dosages and prescriptions. Prioritizing precise diagnosis and enhancing oral health before dental procedures and in patients' everyday routines is essential. This article identifies and summarizes the most frequent clinical and operative scenarios in dental practice, including endodontics, acute alveolar abscess management, extractive oral surgery, periodontology, and implantology. It suggests potential guidelines to decrease antibiotic prescription and usage while maintaining high success rates and low complication rates. The patient categories that need antibiotics for existing conditions are also summarized. Establishing particular standards for antibiotic therapy is crucial in reducing the potential of antimicrobial resistance. Recent evaluations show that in dentistry, lowering antibiotic use by carefully evaluating patient conditions and interventions might enhance efficacy, decrease unwanted effects, and promote individualized treatment.</p> <p><strong>Keywords:</strong> Antibiotics, Oral infections, Antimicrobial resistance, Dental medicine.</p> Faisal Alshail*, Turki Almohaid Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-02 2024-03-02 19 01 213 224 DETECTION AND REMOVAL OF SEASONAL AFM1 OCCURRENCE IN VARIOUS MILK SAMPLES COLLECTED FROM DIFFERENT SHOPS OF LAHORE https://www.acgpublishing.com/index.php/CCB/article/view/306 <p>Aflatoxin shows carcinogenic results in hepatocellular carcinoma, mutations and primary immunodeficiency disorders.&nbsp; Aflatoxin M1 is found in milk of animals fed on aflatoxin B1 contaminated food. AFM1 detection is being done by different techniques like thin layer chromatography, high-performance liquid chromatography and enzyme-linked immunosorbent assay, among these ELISA shows more efficacy regarding its diagnosis because it takes short time, small volume of sample is required, and also its budget friendly. The European Union has set range of AFM1 limit as 0.05 ppb in milk while 0.5 ppb limit by the Food and Drug Administration. In this study a total of 100 milk samples were tested, 50 during summer (25 branded and 25 non-branded) and total 50 during winter (25 branded and 25 non-branded), and the results were compared by using IBM SPSS Statistics 28.0 for windows. Results showed that 6% branded milk samples having Mean ± SD of 1.38±0.255 and 16% non-branded milk samples having Mean ± SD of 1.33±0.462 were found beyond the permissible levels of AFM1 as set by FDA. Brand names were kept confidential due to ethical values while ensuring the integrity and generalizability of the research findings. Seasonal variations showed more contamination in winter than summer, both in branded (6% and 0.0%) and non-branded milk samples (20% and 12%). Four lactic acid bacteria isolated from local yoghurt namely; <em>Lactobacillus rhamnosus</em>, <em>Lactobacillus bulgaricus</em>, <em>Lactobacillus plantarum</em>, and <em>Streptococcus thermophilus</em> showed percentage bound aflatoxin M1 of 78.70%, 54.40%, 50.50%, and 37.10% with Mean ± SD of 55.18±0.173 after 24h incubation period. It is essential to test AFB1 contaminated stored feed daily and apply steps and modern methods to remove aflatoxins from food to ensure health fitness without deteriorating the quality and texture of food.</p> <h1><em>Keywords: </em>Aflatoxin B1, aflatoxin M1, enzyme-linked immunosorbent assay, lactic acid bacteria, yoghurt, percentage decontamination.</h1> Muhammad Luqman*1, Amina Arif1, Naseem Zahra2, Usman Wajid*1, Sana Abid1 . Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-28 2024-03-28 19 01 422 433 EFFECT OF MILKING FREQUENCY ON THE HYGIENIC AND NUTRITIONALLY QUALITY OF RAW MILK IN THE MID-NORTHERN REGION OF ALGERIA https://www.acgpublishing.com/index.php/CCB/article/view/399 <p>The objective of this study was to determine the effects of reduced milking frequency on nutritional and microbiological cow’s milk quality. Once-daily milking on a standard diet (ODM); 3-times daily milking on a standard diet (TDM) cows were assigned from 06 February to 30 May. Cows were on average 218 d into lactation at the start of the trial, and all cows were managed similarly throughout the trial. Milk yields and gross milk composition of cows on all treatments were measured. Results of this study showed a significant decrease in the average milk nutritional quality in TDM as compared to ODM as fat, lactose, protein, casein rates by 15, 8, 3.9 and 5.5% respectively.&nbsp; In addition, TDM decreased the minerals and vitamins levels by 5.8% as compared to milk obtained by ODM. In addition, the application of TDM in the milking affects the milk physical properties by the decrease of the milk conductivity, density and freezing point by 3.29, 1.07 and 8.1% as compared to ODM milk. Moreover, the practice of TDM affects the milk bacteriological quality by the increase of total bacteria count (TBC) (from 11.6 to 13.8), total aerobic mesophilic flora (FMAT) (from 6,4 to 7,8); total coliforms (TCol) (from 4,6 to 5.7); fecal Coliforms (FCol) (from 3,2 to 4.2).&nbsp; Additionally, TDM increase significantly the Sulphite reducing Clostridium (SRC), mods and yeasts counts in milk as compared to ODM.&nbsp; In fact, the improvement of hygienic milking conditions through applying good hygiene practices and new techniques has made it possible to reduce the microbial load of the raw milk samples analyzed. Therefore, the reduction in milk production in ODM was completely compensated by an increase in the concentration of milk components as fat, lactose, protein, casein, minerals and vitamins rates as compared to TDM.</p> <p>Keywords: bacterial flora; improved conditions; raw milk. wholesomeness.</p> Silarbi Tayeb1, 2, Laabas Saadia 2, Tefiel Hakim2, Fatiha Abdellah 3, Ferjeni Zouidi 4, Khaled Hamden 1* Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-14 2024-04-14 19 01 511 519 EXPLORING LOCAL WISDOM THROUGH PROJECT-BASED LEARNING: A CASE STUDY OF THE APPLICATION OF ETHNOSCIENCE MODELS https://www.acgpublishing.com/index.php/CCB/article/view/823 <p>Local wisdom is a valuable cultural heritage and needs to be preserved. One way to preserve it is to integrate it into learning. This research explores how the ethnoscience model can be applied in project-based learning to explore local wisdom. This research uses a qualitative approach. The data collection technique in this research is a literature study. The data that has been collected is then analyzed in three stages, namely data reduction, data presentation, and drawing conclusions. The research results show that the ethnoscience model is an effective tool for exploring local wisdom through project-based learning, which can be implemented by identifying local wisdom, organizing projects, combining knowledge, developing critical thinking skills, and implementing an ethnoscience approach. The ethnoscience approach can be carried out by reconstructing natural science in the customs and culture that exist in society to be developed into scientific science. Applying the ethnoscience model can help students understand scientific concepts, increase curiosity and interest in science, appreciate local wisdom, and develop 21st-century skills.</p> <p><strong>Keywords</strong>: Local Wisdom, Project Based Learning, Ethnoscience Model</p> Oria Lasmana1*, Festiyed2, Yerimadesi3, Abdul Razak4, Muhyiatul Fadilah5 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-10 2024-05-10 19 01 686 693 MODIFICATION OF SCHIFF BASE OF CHITOSAN DERIVATIVES AND ITS APPLICATIONS VIA GREEN METHODS https://www.acgpublishing.com/index.php/CCB/article/view/843 <p class="AbstractandHeaderIntechOpen" style="margin-bottom: 0in; text-align: justify; line-height: 115%;"><span style="font-size: 12.0pt; line-height: 115%; font-family: 'Times New Roman',serif; color: windowtext; font-weight: normal;">Biopolymers have turned out to be very attractive as they`re degradable, biocompatible, non-toxic and renewable. Due to the intrinsic reactive amino businesses, chitosan is colorful within the midst of various biopolymers. Using the flexibility of these amino businesses, several structural changes have been performed on chitosan through sure chemical reactions. Chemical modification of chitosan through imine functionalization is huge as it recommends the ensuing chitosan-based totally definitely Schiff bases (ChSBs) for the vital applications within the fields like catalysis, water treatment, biology, sensors, etc. ChSBs are usually synthesized with the resource of the usage of the Schiff condensation reaction amongst chitosan amino organizations and carbonyl compounds with the removal of water molecules. In this review, we first introduce them to be had synthetic techniques for the coaching of ChSBs. Then, we speak the natural applications of ChSBs inclusive of antimicrobial activity, anticancer activity, drug carrier ability, antioxidant activity and tissue engineering capacity. Successively, the applications of ChSBs in specific fields together with catalysis, adsorption and sensors are demonstrated. Here, covers the green synthesis of ChSBs using non-traditional inexperienced techniques including microwave irradiation, inexperienced solvent, ultrasound irradiation, and one pot synthesis. These techniques are energy-green and greener variations of the traditional condensation techniques. On the other hand, modification of chitosan Schiff base polymer derivatives by using different nanoparticles and beta-cyclodextrine for modifying the physical and chemical properties of ChsBs. Then, the generated polymers were used in various fields such as ammonia sensing, antimicrobial activity, bone tissue engineering, and others.</span></p> Ahmed G. Taha, M. F. Radwan, Mohamed E. Abdu, Nada M. Ali, Mohamed R. Eletmany Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-26 2024-10-26 19 01 1901 1911 ANALYSIS OF THE CAUSE AND IMPROVEMENT OF VARIABLES IN MEDICAL LABORATORIES https://www.acgpublishing.com/index.php/CCB/article/view/859 <p>Medical laboratories play a crucial role in the healthcare system by providing accurate and timely diagnostic information to healthcare providers. However, several variables can impact the quality and reliability of laboratory results, leading to potential errors in patient care. This essay aims to analyze the causes of variables in medical laboratories and propose improvements to enhance the accuracy and efficiency of laboratory testing. By critically examining the literature, this essay will provide a comprehensive understanding of the challenges faced by medical laboratories and suggest strategies to mitigate these challenges.</p> Anood Abdurahman Aloumi, Ghidaa Abdullah Fakih, and Buthaynah Abdalrahman Alodhayb Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-01 2024-02-01 19 01 1102 1105 IN VIVO EVALUATION OF ANTI-THALASSAEMIC ACTIVITY OF TERMINALIA CATAPPA CRUDE EXTRACTS IN SWISS ALBINO MICE https://www.acgpublishing.com/index.php/CCB/article/view/875 <p>Iron overload disorders, such as thalassemia, pose significant health challenges worldwide. In this study, we evaluated the efficacy of <em>Terminalia catappa </em>ethyl acetate crude extract (TCEACE) in reducing serum Fe³⁺ levels. Leaves of <em>Terminalia catappa</em> were collected, dried, and sequentially extracted using chloroform, acetone, and ethyl acetate. In this animal study, male Swiss Albino mice were used to evaluate the effects of <em>T. catappa</em> ethyl acetate crude extract (TCEACE) on iron overload. The mice received intraperitoneal injections of iron dextran to induce iron overload, mimicking thalassemia-related chronic iron accumulation. TCEACE was administered at different dosages, and serum iron levels were assessed. Our results demonstrate that TCEACE significantly outperforms the standard drug (DFO) and effectively mitigates iron overload. Both group-5 (50 mg/kg TCEACE) and group-6 (100 mg/kg TCEACE) exhibited marked reductions in serum iron levels, emphasizing a dose-dependent response. These findings highlight TCEACE as a promising natural alternative for managing iron-related conditions, warranting further investigation for clinical applications in patients with iron overload disorders.</p> Priyanka C, Jyothi B Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-10 2024-08-10 19 01 1376 1385 STUDY OF HISTOLOGICAL FEATURES AND EXPOSURE OF HEAVY METALS IN BREAST TISSUES AND FOOD MATERIALS IN PROGRESSION OF MAMMARY TUMORS IN BREAST CARCINOMA PATIENTS https://www.acgpublishing.com/index.php/CCB/article/view/895 <p>Cancer is an irregular growth of abnormal cells within body. Breast cancer is prevalent in both developed and underdeveloped countries, with higher mortality rate. Various metals are carcinogenic, contributing to develop different types of cancer. This work aimed to assess the histological characteristics of patients and investigate the role of metals in breast tissue and various food items. Clinical data were collected from Jinnah Hospital, Lahore, through questionnaires to participants who provided informed consent prior to data collection. Samples of breast tissue, soil, water, buffalo milk, chicken meat, and beef were obtained from both control and case groups and analyzed for metal accumulation using Atomic Absorption Spectroscopy. The mean age of patients was 48 years, with significant differences observed across age groups. Majority of patients were diagnosed at Stage II. Triple-negative, with invasive ductal carcinoma, was most prevalent type. More number of participants was from Lahore city, with higher frequency in urban areas than rural. Levels of heavy metals, particularly iron and zinc, were found significant impact, whereas lead did not show significant effect. In conclusion, triple-negative and invasive ductal carcinoma were most common types observed. Elevated levels of iron and zinc in breast tissue, water, and milk were associated with cancer development, in urban areas. Zinc levels were inconsistent, and lead had no significant impact. To mitigate the risk, it is crucial to enhance early detection efforts and monitor heavy metal levels in water and milk, with a focus on iron and zinc, to reduce environmental hazards.</p> Muhammad Farooq, Marium Zafar, Ayeza Hussain, Saira, Hafiza Fizzah Riaz, Fouzia Tanvir, Sidra Aslam4, Yasir Nawaz, Ibrar Hussain, Fizza Rimal Butt, Saba Munir, Anum Saleem, Ayesha Abbas, Kirn Kashaf Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-20 2024-05-20 19 01 1513 1529 RADIATION DOSE OPTIMIZATION IN PEDIATRIC IMAGING: PRACTICES AND PERCEPTIONS AMONG SAUDI ARABIAN RADIOLOGISTS https://www.acgpublishing.com/index.php/CCB/article/view/914 <p>Radiation dose optimization is of paramount importance in pediatric medical imaging due tochildren's increased susceptibility to radiation-induced harm and their longer life expectancycompared to adults. This study aimed to comprehensively investigate the current practices andperceptions related to radiation dose optimization in pediatric imaging among radiologistspracticing in Saudi Arabia. An online survey was disseminated to radiologists across varioushealthcare institutions in the country, collecting data on their specific pediatric imaging protocols,dose reduction techniques employed, and perceived barriers to achieving optimal doseoptimization.</p> <p>The survey results reveal that while the majority of Saudi radiologists possess a goodunderstanding of the significance of dose optimization and implement certain dose reductionstrategies, there is still considerable room for improvement in their practices. The key areasidentified for enhancement include increasing the use of dose monitoring software, developing andimplementing standardized pediatric imaging protocols across institutions, providing morecomprehensive training for radiologists on optimization techniques, and fostering bettercommunication with referring physicians to ensure appropriate study selection and doseoptimization.Respondents identified several barriers to implementing optimal dose optimization, including thelack of pediatric-specific imaging protocols, time constraints in clinical practice, and concernsabout compromising diagnostic image quality. This study provides valuable insights into thecurrent state of radiation protection practices in pediatric imaging in Saudi Arabia and highlightspotential avenues for further optimizing radiation dose to ensure the safest and most effectiveimaging care for children.</p> Abdullah Saqer Mounir Alotaibi, Ayman Edrees Mohammed Bin Basheer, Bader Muflih Hlal Alotaibi, Fahad Abdulla Masfer AlOtaibi, Hamad Abdullah Saad Alotaibi, Ibrahim Saghir Ali Alissa, Saad Mansour Hassan Al Dosari, Tareq Abdullah Alwan Alqarni Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-03 2024-10-03 19 01 1713 1726 THE APPLICATION OF DEEP LEARNING IN ANALYSING ELECTRONIC HEALTH RECORDS FOR IMPROVED PATIENT OUTCOMES. https://www.acgpublishing.com/index.php/CCB/article/view/191 <p>Deep learning techniques like neural networks show promise for extracting insights from electronic health records (EHRs) to enhance clinical decision-making and improve patient outcomes. Recurrent and convolutional approaches demonstrate particular efficacy for predictive tasks based on longitudinal EHR data. However, significant barriers around model interpretability, data constraints, and real-world integration must still be addressed for broader adoption. This paper reviews recent literature on deep learning for EHR analysis including predictive modelling, imaging, and patient risk stratification. Based on promise but with challenges remaining, recommendations focus on methods to enable translation into clinical practice through improved user-centered design. If key next steps around transparency and standards are achieved, hybrid deep learning EHR systems hold immense potential to augment data-driven precision medicine.</p> <p><strong><em>Keywords:</em></strong> <em>Deep Learning, Electronic Health Records, Clinical Decision Support, Patient Stratification, Neural Networks, GAN, CNN, RNN</em></p> Sathishkumar Chintala Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-02 2024-02-02 19 01 EFFECT OF SPRAYING NANO-AMINO ACIDS AND IRON ON SOME YIELD CHARACTERISTICS AND THE CHEMICAL AND MEDICINAL CONTENT OF TWO CULTIVARES OF FENUGREEK PLANT, TRIGONELLA FOENUM-GRAECUM L https://www.acgpublishing.com/index.php/CCB/article/view/292 <p>The experiment was carried out in the nursery of the Agricultural Division of the University of Kufa in Najaf Governorate for the season 2022-2023 to study the effect of spraying nano-amino acids and iron on some yield characteristics and the chemical and medicinal content of two varieties of the fenugreek plant, <em>Trigonella foenum-graecum </em>L., the local variety and the Indian variety.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The experiment included eight treatments. It is an interaction between two varieties of fenugreek plant (local A1 and Indian A2) with four spray treatments: T1 control (distilled water), T2 (200 mg. L<strong><sup>-1</sup></strong>) nano-iron, T3 (2 ml. L<strong><sup>-1</sup></strong>) nano-amino acids, and T4. (200 mg.L <strong><sup>-1</sup></strong>+ 2 mL.L<strong><sup>-1</sup></strong>) nano-iron and nano-amino acids. A factorial experiment was carried out using a completely randomized design (C.R.D) with two factors: varieties and spray treatments, with three replicates. The means were compared according to Duncan's multinomial test at the probability level of 0.05.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Measurements were taken at the end of the growing season. The results showed that foliar spraying of nano-amino acids and iron led to improvement in yield&nbsp; indicators and the chemical and medicinal content of all studied&nbsp; traits compared to control plants. The results of the study also showed that the T3 treatment (nano amino acids) gave the highest rates in most of the traits under study (pod length, number of pods, number of seeds, Choline, Peroxidase and Catalase when interacting with the local variety A1, as it reached 11.03 cm, 54.63 (pod. Plant<strong><sup>-1</sup></strong>), 14.00 (seed. pod<strong><sup>-1</sup></strong>), 0.44, 1.55, 1.42 (mg. ml<strong><sup>-1</sup></strong>), respectively. As for the Indian variety A2, it gave the highest rate of the alkaloid Trigonelline when interacting with treatment T3, amounting to 0.79( mg. ml<strong><sup>-1</sup></strong>).</p> <p><strong>Keywords: Fenugreek, nano-iron, nano-amino acids, Trigonelline, Choline.</strong></p> Amel Hussein khudhiar AL- Ibraheemi1 , Saadon Abdul-Hadi Saadon AL-Ajeel2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-19 2024-03-19 19 01 294 308 ASSESS THE APOPTOTIC EFFECT OF CRUDE EXTRACT OF ROOT POWDER OF WITHANIA SOMNIFERA IN BREAST CANCER CELL LINE https://www.acgpublishing.com/index.php/CCB/article/view/575 <p><strong>Background:</strong> Cancer is one of the greatest health challenges in the developing countries. About half (51%) of cancers occurred in developing countries in 1975. In 2018, this proportion was 55% in 2018 and will projected to reach 61% in 2050. Notably, breast cancer alone contributes to 30% of female cancer cases. It was evident that bioactive component (withaferin –A) of root of <em>Withania somnifera</em>&nbsp;&nbsp; has capacity to work against the breast cancer. In this present study, the crude methanolic extract of root of <em>Withania somnifera</em>&nbsp;&nbsp; screened for in vitro apoptotic activity on MCF-7 and MDA-MB-231 cell line.&nbsp; In Ayurveda, <em>Withania somnifera</em>&nbsp;&nbsp; is commonly known as Ashwagandha, its roots are specifically used in medicinal and clinical applications. It possesses numerous therapeutic actions which include anti-inflammatory, anticancer, sedative, hypnotic and narcotic.</p> <p><strong>Objectives:</strong> To Assess the apoptotic activity of crude extract of root of <em>Withania somnifera</em>&nbsp;&nbsp; on breast cancer cell line.&nbsp;&nbsp;</p> <p><strong>Materials and Methods:</strong> MDA-MB-231 and MCF-7 breast cancer cell lines, DMEM complete media, 10% fetal bovine serum (FBS), MEM nonessential amino acids, gentamicin and 10μg/mL insulin. MCF-7 and MDA-MB-231 cells were treated with different concentration of sample (crude extract of root powder of <em>Withania somnifera</em>&nbsp;&nbsp; for 24 hrs incubation. Cytotoxicity was measured by MTT assay. The morphological change of untreated (Control) and treated cells were observed under digital inverted microscope and photographed.</p> <p><strong>Results:</strong> The lower concentration of sample show less cytotoxic activity on both cell line MCF-7 and MDA-MB-231. Higher concentration of sample show more cytotoxic activity on both cell line MCF-7 and MDA-MB-231.The IC<sub>50</sub> value of crude extract of root powder of <em>Withania somnifera</em> against both MCF-7 and MDA-MB-231 was determined.</p> <p><strong>Conclusions:</strong> The crude methanolic extract of root of <em>Withania somnifera</em>&nbsp;&nbsp; have anticancer potential but additional studies required.</p> <p><strong>Keywords:</strong> Apoptosis, <em>Withania somnifer</em>, cancer, MCF-7, MDA-MB-231, withaferin A.</p> Anni1 and Munawar Fazal2* Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-20 2024-04-20 19 01 632 643 PHYSICOCHEMICAL CHARACTERISTICS OF THE SOIL IN SACCHARUM OFFICINARUM L. (SUGAR CANE) CULTIVATION IN THE PROVINCE OF PASTAZA, ECUADORIAN AMAZON https://www.acgpublishing.com/index.php/CCB/article/view/831 <p>The Ecuadorian Amazon is a mega-diverse ecological niche in flora and fauna. Currently, crop areas that serve as a source of sustenance for rural populations have increased. It was essential to evaluate the physicochemical characteristics of the soil in sugarcane crops (Saccharum officinarum L.) in the Pastaza province of the Ecuadorian Amazon to evaluate its fertility in comparison to a primary forest (PF). The composite soil samples were collected in five agricultural production units (APUs) and PF as a comparison agent at a depth of 0.15 m. The physicochemical variables evaluated were: bulk density, texture, pH, organic matter, macronutrients, micronutrients, and base ratio. High concentrations of organic matter were found (11.99 to 12.78%), as well ashighly acidic soils (pH 3.90 to 4.67) and sandy loam and silty soil textures. Macronutrients were generally medium to low in concentration, and micronutrients medium to high. 64.70% of the variables are concentrated in CP1 and CP2; as factors with the greatest contribution to soil fertility, they are affected by P, NH<sub>4</sub>, clay, B, S, Mn, Fe, silt, sand, Mg, Zn, sum of bases, Ca, K, and Cu. The physicochemical results of the soil with S. officinarum and PF cultivation demonstrated a characteristic behavior of Amazonian soils. S. officinarum did not exert any influence on soil fertility, and it adapted fully to the nutritional and highly acidic conditions of the Amazonian soils.</p> <p><strong>&nbsp;</strong><strong>Keywords:</strong>Macronutrients, micronutrients, soil texture, principal component.</p> González Víctor, Jaque Darwin, Salazar-Álvarez Edgar Andrade-Yucailla Verónica, Hidalgo-Guerrero Irene, Saltos-Espín Rubén Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-23 2024-05-23 19 01 772 787 PRECONCEPTION HEALTH COUNSELING AND STUNTING PREVENTION LITERATUR REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/850 <p>This paper presents the results of a literature review on the importance of preconception health counseling to prevent stunting in newborns. Literature searches refer to the Preferred <em>Reporting Items for Systematic Reviews </em>(PRISMA) guidelines. The literature in this study is mostly sourced from online journals accessed from scientific article sites with open access, such as ScienceDirect, PubMed and ProQuest. The strategy used was <em>the PICOS framework,</em> resulting in 171 articles. This article was then further analyzed in the title and abstract, and 12 eligible articles were obtained. Various interventions have been carried out to prevent stunting, including improving nutrition through nutrient supplementation. This nutrition intervention must be supported by various sensitive interventions such as education and counseling to improve community knowledge and skills in stunting prevention efforts. In some articles, it is found that counseling and counseling efforts must be carried out using directed and theory-based modules.</p> Sitti Salmiyah A. Bahruddin, Aminuddin Syam, Nurhaedar Djafar Suriah Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-05 2024-07-05 19 01 1017 1020 POTENTIAL COMPLICATIONS OCCURING AS A RESULT OF INCIDENTAL DETECTION OF UNTREATED ASYMPTOMATIC APICAL PERIODONTITIS. REVIEW OF LITERATURE. https://www.acgpublishing.com/index.php/CCB/article/view/866 <p>The incidental detection of asymptomatic apical periodontitis prompts the question of whether or not this lesion should be treated. Arguments favoring treatment are that the inflammation may cause pain in the future, may enlarge, or may negatively affect the host's resistance. Reasons for not treating may be that treatment weakens the tooth, may cause iatrogenic damage, and that treatment is expensive and burdensome for the patient and does not lead to complete recovery in all cases. A lack of scientific evidence exists to support either option, whether it involves treating the lesion or not.</p> Shugaa Nasir Alotaibi, Khalid M Alotaibi, Abdulaziz A Alamro, Sharifah S Alzaidi, Maha M Alotaibi, Nada A Softah Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-31 2024-07-31 19 01 1168 1191 MODERN APPROACHES TO QUAIL NUTRITION: ENRICHED FEEDS AS A STRATEGY FOR ENHANCING MEAT PRODUCTIVITY https://www.acgpublishing.com/index.php/CCB/article/view/883 <p><strong> </strong> To enhance the meat productivity of quails, as well as to increase production volumes and improve the quality of poultry products, it is necessary to incorporate unconventional feed additives into the birds' diet. These additives promote the normalization of metabolic processes and improve nutrient digestibility. This article presents research findings on the meat productivity and nutritional value of Texan quail meat when using a compound feed enriched with the phytobiotic BioFeed-P and extruded corn. In the experimental group fed with the formulated compound feed, a 3.84% or 12.5 g advantage in live weight was observed by the end of the experiment. The absolute weight gain in the experimental group was 59.6±5.6 g, compared to 45.5 g in the control group. A notable advantage was also observed in the chemical composition of the meat, with the experimental group having a higher protein content of 21.89%. The fat percentage was slightly higher in the experimental group at 3.16%, with no significant differences in ash content between the groups. These findings are of interest to specialists in poultry farming and animal nutrition, and may prove valuable in formulating diets for fattening quails.</p> Dinara Zhanabayeva, Assel Paritova, Leila Sultanayeva, Dаnara Mussagiyeva, Yevgeniy Maier, Botagoz Aitkozhina, Dilora Senkebayeva, Nurlygul Yeleugaliyeva, Rakhimtay Tleulessov Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-19 2024-10-19 19 01 1421 1439 THE RELATIONSHIP OF PERCEIVED PARENTING STYLES AND EMOTIONAL INTELLIGENCE OF GENERATION Z AMONG SELECTED SCHOOLS IN CEBU CITY https://www.acgpublishing.com/index.php/CCB/article/view/905 <p><strong>Abstract - </strong><em>The way parents interact with their children can have a big impact on how their emotional intelligence develops. The purpose of this study is to identify emotional intelligence and which parenting styles are most perceived among Cebu City's Generation Z, as well as the relationship between those parenting styles and emotional intelligence. This study utilized a quantitative approach with a descriptive correlational research design using standardized tests such as the Perceived Parenting Style Scale and the Emotional Intelligence Self-Assessment Tool. The researchers collected data from 385 respondents who were 18– 25 years old and lived in Cebu City. The result revealed that the most perceived parenting style of Generation Z among selected schools in Cebu City is authoritative parenting, and the respondents have a high level of emotional intelligence. Moreover, the results also showed that the respondents have high levels of emotional intelligence in all of its domains. However, the result also found that there is no significant correlation between the three perceived parenting styles when compared individually to the domains of emotional intelligence.</em></p> Antone L. Abellanosa, Ma. Mia Monica H. Chavez, Gieannil R. Nacario, Karla Mae E. Rivera, Ronald C. Yrog-Irog Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-12 2024-09-12 19 01 1613 1625 MATERNITY LEAVE POLICIES AND WAGE DISPARITY ON WOMEN WORKFORCE IN HARYANA https://www.acgpublishing.com/index.php/CCB/article/view/923 <p>The state of Haryana has been grappling with the issue of low female workforce participation, with only 23.2% of women employed compared to 75.4% of men. Maternity leave policies and wage disparity are two significant factors that can impact women's decision to join and stay in the workforce. This study aims to explore the impact of maternity leave policies and wage disparity on women's workforce participation in Haryana. This study examines the interplay between maternity leave policies and wage disparity among women in Haryana's workforce. In scenarios where maternity leave is generous and accessible, women tend to experience improved job retention and career progression, mitigating wage gaps. Conversely, in environments with limited or inflexible leave, women face increased job insecurity and stagnation in earnings. A mixed-methods approach was adopted, combining both quantitative and qualitative data collection and analysis methods. A survey was conducted among 200 women employees in various sectors in Haryana, while 30 in-depth interviews were conducted with women who had taken maternity leave and returned to work. The results show that the current maternity leave policy of 26 weeks is inadequate, as many women reported having to take unpaid leave or compromise on their job roles during this period. Wage disparity was found to be a significant deterrent, with women earning an average of 22% less than their male counterparts. The study highlights the need for a more comprehensive and supportive maternity leave policy, as well as measures to address wage disparity. Recommendations include increasing the duration of maternity leave, introducing flexible work arrangements, and implementing policies to address wage disparity. The findings of this study have important implications for policymakers and employers in Haryana, highlighting the need for a more inclusive and supportive work environment that enables women to thrive in their careers.</p> Ms. Priya Verma Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-21 2024-10-21 19 01 1852.1875 1852.1875 TO OBSERVE THE LOCALISATION OF PLACENTA IN RELATION TO PREVIOUS CESAREAN SECTION AND IT'S FETO-MATERNAL OUTCOME https://www.acgpublishing.com/index.php/CCB/article/view/206 <p><strong>Objective:</strong></p> <p>To observe the localization of placenta in relation to previous cesarean section and its feto-maternal outcome</p> <p><strong>Materials and method:</strong></p> <p>A cross sectional study was conducted among 246 Eligible participants (participants with previous LSCS and current pregnancy ≥ 20 weeks) Detailed history including menstrual history, obstetrics history, past history, personal history, marital history, family history of the patient was taken. General and obstetrical examination were carried out. All women were undergone to transvaginal or transabdominal ultrasound. Determining the placental location or any abnormal placentation with the transabdominal obstetric scan done between 28 weeks period of gestation and 42 weeks period of gestation, reassessed after 36 weeks or when patient presents in labor or with bleeding per vagina. The patients are followed up to delivery and the maternal and fetal outcomes are noted.</p> <p>&nbsp; <strong>RESULTS</strong></p> <p>&nbsp;The mean age of the study participants was 28.69 years among which 90.7% of the cases were booked History of previous one LSCS was reported among 71.1% of the women while 28.9% were having two LSCS. Placenta previa was observed among 14.2% of the women who had previous history of LSCS. Fundo-posterior and fundo-anterior placenta was seen among 37.8% and 14.6% of the women respectively. Fundo-lateral and low-lying placenta were seen among 24% and 9.3% of the women respectively. Placenta previa and accreta are the major factors for post-partum hemorrhage Proportion of preterm birth was 10.1% Proportions of meconium-stained liquor and poor APGAR score (&lt;7) were observed among 4.5% each of the study participants.</p> <p>Placenta previa was identified in 14.2% of women with a history of LSCS. To reduce the occurrence of placenta previa, it is important to reduce the number of primary cesarean procedures and promote vaginal births. For optimal care, if a patient must have c-section, routine prenatal examinations and identification of high-risk groups should be performed.</p> <p><strong>Keywords:</strong> Cesarean section, Placenta previa, Maternal outcome, Fetal outcome.</p> Dr. Radhika Parmar, Dr. Deepa Kirar, Dr. K Padma Sandeepthi, Dr.Yashika Jain Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-16 2024-02-16 19 01 162 183 FEEDING HABITS OF INTRODUCED INVASIVE SPECIES PIKEPERCH SANDER LUCIOPERCA (LINNE, 1758) IN THE RESERVOIR OF GHRIB DAM (NORTHWEST ALGERIA) https://www.acgpublishing.com/index.php/CCB/article/view/304 <p>When an introduced fish species successfully adapts to new ecological conditions, they significantly reduce the number of indigenous species. This paper aims to determine impacts that introduction of invasive species Sander lucioperca (Linnaeus 1758) has on native fish species in the reservoir of Ghrib dam (western Algeria). The diet of the introduced pikeperch was studied from September 2020 to August 2021. Trophic activity was assessed using the digestive vacuity coefficient (Cv). The index of relative importance (IRI), which combines frequency of occurrence (F), the number (Cn), and restored weight (Cp) of different ingested prey, was used to characterize the relative importance of different food taxa. Qualitative and quantitative variations in diet were studied according to pikeperch size (small, medium and large) and season. In total, 193 stomachs were empty, corresponding to a digestive vacuity coefficient of 44.47%. Qualitative study of stomach contents indicates that this species is omnivorous, with an ichtyophage trend. Three groups of prey were identified: Amphipodan (IRI = 1.03; Gammarus sp.), Dipteran (IRI = 4.73; Chironomus sp.) and primarily fishes (IRI = 94.24; Cyprinus carpio, Rutilus rutilus, and Sander lucioperca). Significant differences in feeding habits occur according to season and pikeperch size, showing also, the risk of cannibalism was highest among the largest pikeperch.&nbsp;</p> <p>KEY WORDS: - Feeding habits, Predation pressure, Sander lucioperca, The Index (IRI), The reservoir of Ghrib dam.</p> Billel Belaifa1,*, Amina Bouamra1, Yasmine I. Arab1, Mohamed H. Kara2, and Abdeslem Arab1 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-26 2024-03-26 19 01 364 379 ANTIOXIDANT ACTIVITY AND PROTECTIVE EFFECT OF THE PHENOLIC FRACTION FROM OLIVE OIL AGAINST LIPID PEROXIDATION INDUCED BY H2O2 AND FECL3 https://www.acgpublishing.com/index.php/CCB/article/view/819 <p>Hydrogen peroxide (H2O2) and iron can be toxic to human cells and produce highly reactive oxygen species (ROS) such as hydroxyl radicals (OH•). These ROS can damage cellular components like DNA, proteins, and lipids, leading to cell injury or death. Olive oil is one of the most important components of the Mediterranean diet characterized by many therapeutic proprieties and health protective effects, mainly attributed to its high content of monounsaturated oleic acid, vitamin and polyphenolic compounds. The aim of this study was to evaluate the <em>in&nbsp;vitro</em> antioxidant activity of the phenolic extracts of two Algerian olive oil varieties (Chemlal and Sigoise) and to determinate their protective effect against lipid peroxidation. We have used Folin-Ciocalteu reagent method to estimate the phenolic content of the studied extracts. The antioxidant activity was determined using three different antioxidant assays (DPPH scavenging activity, reducing power and hydrogen peroxide<strong> s</strong>cavenging assay). The protective effect of olive oil extract against lipid peroxidation was evaluated in an <em>in vitro</em> model of rat liver homogenates through the production of TBARS. The quantitative analysis results showed that the phenolic extracts of Algerian olive oil are rich in phenolic compounds mostly flavonoids, with the highest content found in Chemlal oil (366.095± 1.01 mg GAE/Kg for polyphenols and 79.065± 0.84 mg QE/Kg for flavonoids). Moreover, the studied extracts showed very important anti-free radical activity and reducing power, wherein Chemlal oil exhibited the highest antioxidant activity.&nbsp; The tested extracts demonstrated a strong protective effect against lipid peroxidation, with Chemlal olive oil showing the highest protective effect. These findings confirmed the medicinal use of Algerian olive oils as natural agents in food and pharmaceutical industries</p> <p><strong>Keywords:</strong>&nbsp; olive oil, polyphenols, oxidative stress, biological activities.</p> Fatiha Abdellah1’2, Khaled Hamden2, Tayeb Silarbi1’2, Noura Ayad 1, Laid Boukraa1, Si Mohamed Hammoudi1 ,Rachida Benaraba1 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-28 2024-04-28 19 01 519 532 EXPLORING HEAVY METAL PRESENCE IN LYCOPERSICUM ESCULENTUM L. AND ITS SOIL SAMPLES : PROXIMITY TO RIVER HASDEO AND AHIRAN IN KORBA DISTRICT, CHHATTISGARH https://www.acgpublishing.com/index.php/CCB/article/view/839 <p>This study investigates the presence of heavy metals in <em>Lycopersicum esculentum L</em>. (tomato) and its associated soil samples in the vicinity of River Hasdeo and Ahiran in Korba District, Chhattisgarh. Heavy metal contamination in agricultural products and soil poses significant environmental and health risks. In this research, samples were collected and analyzed for the concentrations of various heavy metals. The analysis was performed using triplicate measurements, and the results were expressed as mean values with standard deviations. The mean concentrations of metals in both tomato and soil samples were calculated. The reported mean concentration of heavy metals are (0.216-1.057) , (0.125- 0.530) (0.444 -0.823) (0.104-1.247) (0.012-0.053) in mg/kg for Zn, Cu, Mn, Fe &amp; Pb respectively for tomato plant. And mean conc. of heavy metals in soil reported as (0.012-0.167) (0.124- 0.044) (0.067- 0.067) (0.098-0.461) (0.012-0.074) in mg\kg for Zn, Cu, Mn, Fe &amp; Pb respectively. The Pearson coefficient correlation between heavy metals also discussed in this research paper. The findings of this study provide valuable comprehensions of heavy metal impurity in agricultural produce and soil in the studied region, aiding in the development of appropriate mitigation strategies to safeguard environmental and human health.</p> <p><strong>Keywords </strong>- Standard deviations, Heavy metals, Vicinity</p> Gayatri Sahu, Rita Bajpai Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-05 2024-06-05 19 01 883 894 SYNDECAN-1 AND RISK FACTORS ASSOCIATED WITH ITS CONCENTRATION IN ACUTE MYELOID LEUKEMIA PATIENTS https://www.acgpublishing.com/index.php/CCB/article/view/857 <p>The study included determining the syndicane-1 concentration in acute myeloid leukemia patients and comparing it with healthy cases, and studying the effects of some risk factors on its concentration in both patients and control group, complete blood count (CBC) including white blood cells, hemoglobin, platelets and blast in bone marrow has been determined, as well as, the concentration of urea, creatinine, the activity of lactic dehydrogenase, systolic and diastolic blood pressure and body temperature. The results showed a significant increase in the concentration of syndicane-1 in patients compared to healthy people, and its concentration increases significantly with age, smoking, body mass index (BMI), blood type (A), duration of disease, chemotherapy, diabetes menopause in women, WBC count, platelet count, hemoglobin and blast% in BM. Our results showed a significant increase in the concentration of creatinine, urea, lactate dehydrogenase activity, and body temperature (Tm) in patients compared to the control. The Pearson correlation coefficient (r) showed a positive correlation between syndicane-1 concentration and creatinine, urea, Tm, and LDH. We concluded that syndicane-1 concentration can be a strong biomarker for the diagnosis of acute myeloid leukemia and endothelial glycocalyx damage.</p> Eman Ali Ahmed Freih, Rana F. Jassim Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-17 2024-07-17 19 01 1079 1091 REFLECTION OF FRUIT TREES UNDER THE INFLUENCE OF ENVIRONMENTAL STRESSES https://www.acgpublishing.com/index.php/CCB/article/view/873 <p>Direct solar radiation affects the process and development of photosynthetic activity on fruit trees and on green plants in general. The influence of solar radiation on leaves can be analyzed using diffuse reflectance and also observing their color. The measurements were carried out with three types of leaves (sun, partial shade and shade) for Santa Maria (pear) variety in two areas under and above water. The reflectance values ​​provide the possibility to determine the parameters that evaluate the activity of the photosynthetic apparatus in two different areas in the same period. The resulting spectrum values allow the determination of brightness, "dominant" wavelength, and photochemical diffuse reflectance index (PRI).</p> Matilda Mema, Kejda Kristo, Emil Xhuvani Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-06 2024-08-06 19 01 1272 1285 BEST PRACTICES IN LABORATORY SAFETY AND BIOSECURITY TO PREVENT ACCIDENTS https://www.acgpublishing.com/index.php/CCB/article/view/892 <p>Laboratory safety and biosecurity are of utmost importance to prevent accidents and ensure the well-being of researchers, staff, and the public. This essay explores the best practices in laboratory safety and biosecurity to prevent accidents. The methodology involved a thorough review of existing literature, including academic journals, books, and reputable sources. The results highlight key strategies and protocols that can be implemented to enhance laboratory safety and biosecurity. The discussion emphasizes the importance of a proactive approach to prevent accidents and mitigate risks. In conclusion, adherence to best practices in laboratory safety and biosecurity is essential to create a safe working environment in research laboratories.</p> Atif Dahfer Alahmari, Mohammed Abdullah almosalam, Amn Owaid Alshammari, Noor Asaad Aljasham, Ghadah Omar Owaidh Almuzaini, Eman Ahmed Ameen Sunyur Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-13 2024-08-13 19 01 THE ROLE OF EXPERT WITNESSES IN CRIMINAL TRIALS: ENSURING SCIENTIFIC RIGOR AND LEGAL RELEVANCE https://www.acgpublishing.com/index.php/CCB/article/view/912 <p>The role of expert witnesses in criminal trials in India is crucial in ensuring the scientific rigor and legal relevance of evidence presented in court. In recent years, the Indian judiciary has recognized the importance of expert testimony in complex cases, particularly those involving scientific and technical evidence. This paper examines the role of expert witnesses in Indian criminal trials, highlighting their significance in ensuring the admissibility and credibility of scientific evidence.</p> <p>In India, the Code of Criminal Procedure (CrPC) and the Indian Evidence Act (IEA) provide a framework for the use of expert witnesses in criminal trials. Section 45 of the IEA defines an expert witness as one who has specialized knowledge or skill in a particular field, which enables him to form an opinion on a matter relevant to the case. The crux of expert testimony lies in its ability to provide objective and unbiased opinions, derived from scientific methods and principles.</p> <p>The paper discusses the challenges faced by expert witnesses in Indian courts, including the need for rigorous cross-examination, potential bias, and conflicting opinions. To address these concerns, the Indian judiciary has developed guidelines for the examination of expert witnesses, such as the use of voir dire to assess their qualifications and impartiality. The paper also highlights the importance of judicial scrutiny in evaluating expert testimony, emphasizing the need for courts to critically analyze the scientific basis of expert opinions and to consider alternative explanations for the evidence presented. Furthermore, it discusses the role of scientific organizations and research institutions in providing expertise to courts and promoting best practices in forensic science. The role of expert witnesses is critical in ensuring scientific rigor and legal relevance in Indian criminal trials. By understanding their role, challenges, and limitations, courts can ensure that expert testimony is credible and reliable, thereby promoting justice and upholding public confidence in the criminal justice system</p> Rupali Sharma Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-30 2024-09-30 19 01 1682 1696 PROMOTION OF DENTAL AND ORAL HEALTH THROUGH THE GIGIKU SEHAT APPLICATION AND HEALTHY DENTAL GYMNASTICS WITH TEACHER ASSISTANCE ON TEETH CLEANING ACTIONS TO PREVENT CARIES IN CHILDREN AGED 10-13 YEARS https://www.acgpublishing.com/index.php/CCB/article/view/175 <p><strong>BACKGROUND:</strong> Caries is one of the chronic diseases experienced by 2.4 billion or 36% of the world's population. Globally, school children who experience caries account for 60%-90% due to lack of health promotion. Mobile mobile&nbsp; is one of the health promotions that can improve the degree of public health.</p> <p><strong>AIM:</strong> Knowing the effect&nbsp; of the application of healthy teeth&nbsp; and healthy dental gymnastics with teacher assistance on the act of cleaning teeth to prevent caries in children aged 10-13 years.</p> <p><strong>METHOD:</strong> The study was conducted at Makassar City Elementary School, South Sulawesi in September 2022 - March 2023. The type of research is a mixed method with two stages of research, stage 1 making healthy dental applications with&nbsp; qualitative methods and stage 2 educational model intervention for 3 (three) months&nbsp; with quasi-experimental methods&nbsp; with&nbsp; the design of the non randomized pretest postest control group design. The number of samples were students of SD Hang Tuah 64 people, SDN Ujung Tanah 54 people and SDN Cambaya 49 people. The research group was divided into 3 (three) with teacher assistance, namely First is SD Hang Tuah with a combination intervention of healthy dental application&nbsp; and healthy dental gymnastics. The second is SDN Ujung Tanah with the intervention of my healthy teeth application. The third is SDN Cambaya with healthy dental gymnastics intervention.</p> <p><strong>RESULTS:</strong> The level of oral hygiene at SD Hang Tuah was significantly different before and after the intervention, while at SDN Ujung Tanah and SDN Cambaya there was no significant difference but there was a difference in mean value.&nbsp; The DMFT scores in the three schools have significant differences, especially&nbsp; the mean value&nbsp; in the Filling aspect&nbsp; has increased which is an indicator of increased awareness to treat caries.</p> <p><strong>CONCLUSION:</strong> The effect of dental health education&nbsp; with the application of healthy teeth and&nbsp; / or healthy dental gymnastics with teacher assistance statistically had a significant effect on SD Hang Tuah, while SDN Ujung Tanah and SDN Cambaya did not have a significant effect but there was a difference in mean values on improving oral hygiene. The DMFT value before and after the intervention statistically has a significant effect, especially in the Filling aspect, there is an increase in the mean value&nbsp; which is an indicator of increased awareness to treat caries.</p> <p><strong>Keywords:</strong>&nbsp; Caries, oral health promotion, oral health behavior</p> Muhammad Nurung1, Andi Zulkifli2, Sudirman Nasir3, Wahiduddin4, Santi Martini5, Harun Achmad6, Anwar Mallongi7, Fridawaty Rivai8 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-01 2024-02-01 19 01 55 65 ADAPTATION OF BRASSICA NAPUS SEEDLINGS TO VARIOUS BIOTIC AND ABIOTIC STRESSES UNDER DARK AND LIGHT REGIMEN https://www.acgpublishing.com/index.php/CCB/article/view/284 <p>Roots of the plants are highly sensitive to interaction with abiotic or biotic components of the soil environment. During current study, 7 days old seedlings of hydroponically grown B. Napus were exposed to different biotic and abiotic stresses including AgNO3, Cinnamic acid, and Pseudomonas syringae under light and dark regimes. Also, the effect of different concentrations of nutrients was analysed by growing the B. Napus seedlings in 1 X, 0.5 X, 0.25 X of Hoagland solution. Data of root exudation of secondary metabolites with to respect to growth rate was noted for each treatment at the end of the week for each abiotic and biotic stress under dark and light at 24, 48 and 72 hours. It was noted that roots of dark grown seedlings exuded remarkably higher quantities of IAA and phenolics as compared to the control. Contrary to this, light exposure reduced the exudation of these secondary metabolites by B. Napus seedlings. Silver nitrate antagonistically affect the seedlings in dark due to the inhibition of the level of IAA, phenolics along with flavonoids and significantly reduced the growth rate. However, under the effect of 200mM cinnamic acid, the growth rate of seedling was improved with the inhibition of secondary metabolites in light condition. Interestingly, exudation of phytoalexins was not influenced conditions of light or dark while silver nitrate reduced its exudation from root in light. In the presence of CA, the light factor became an important modulator of phytoalexins exudation showing contrasting response. As expected, greater availability of nutrients(1 X Hoagland solution) positively influenced the release of secondary metabolites by roots. The effect of 200Mm of AgNO3 and P. syringae was adverse on B. Napus as both inhibited the level of overall exudation of flavonoids and phytoalexins in dark grown seedlings.</p> Fawad Ali1, Farhad Ali1*, Ibtisam M. Alsudays2, Siham M.AL-Balawi3, Zahid Khorshid Abbas 3 Muneera A. Saleh4, Roobaea Alroobaea5, Muhammad Junaid Yousaf6 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-12 2024-03-12 19 01 267 282 ENHANCING ANTIOXIDANT STATUS, PRODUCTIVE AND REPRODUCTIVE PERFORMANCE FOR POST-MOLT BROILER BREEDERS BY USING MACA POWDER (LEPIDIUM MEYENII) https://www.acgpublishing.com/index.php/CCB/article/view/351 <p>This study was designed to evaluate the effects of using Maca powder (<em>Lepidium meyenii</em>) in the diet on egg production traits, fertility, hatching characteristics, and some blood parameters for broiler breeders (Arbor-Acres Plus) post-molting. A total of 180 Females and 15 Males, 62 weeks old, Arbor Acres Plus broiler breeders were induced to forced molting with ZnO in diet with a moderate decrease in lighting schedule from 16 to 8 h and feed restriction at 50 g/bird daily. Post-molting birds were randomly divided into three groups according to Maca powder as follows: the 1<sup>st</sup> group (M0) was fed the basal diet without Maca, while the 2<sup>nd</sup> (M1) and the 3<sup>rd</sup> (M2) groups were fed the basal diets supplemented with Maca powder at the levels of 1 and 2g Maca/kg diet, respectively.All groups were replicated into five replicates of 13 birds each (1 male + 12 females). The trial lasted for 12 weeks. According to the present study, the laying rate was significantly (P&lt;0.05) increased by using Maca powder at different levels, without affecting egg weight and egg mass. Furthermore, the fertility rate and hatchability of settable eggs were significantly (P&lt;0.05) increased by using Maca powder at 1 and 2g /kg diet. Additional results showed that using Maca powder significantly (P&lt;0.05) decreased early embryonic mortality rate compared with control. Data indicated that Maca had no significance on the hatchability of fertile eggs, chick weight, and late embryonic mortality rate. The results of blood biochemical parameters revealed that serum cholesterol was significantly (P&lt;0.05) reduced by using Maca powder. Data indicated that TSD and TAOC were significantly (P&lt;0.05) higher in the M1 and M2 groups compared with control. It could be concluded that Maca powder (<em>Lepidium meyenii</em>) administration in diets for post-molt broiler breeders at levels of 1 and 2g /kg could be improved productive and reproductive traits also, enhance antioxidant status.</p> <p><strong>Keywords: </strong>Maca powder, broiler breeders, performance, antioxidant status, molting</p> Mohammad A. Elsagheer*1 and M. Kh. Wadea2, Nada M. Ali3, Mohamed R. Eletmany*4,5 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-19 2024-01-19 19 01 485 499 KINETIN-MEDIATED ALLEVIATION OF CADMIUM STRESS IN MUNG PLANTS: A COMPREHENSIVE ANALYSIS OF ANTIOXIDANT RESPONSE AND GROWTH ENHANCEMENT https://www.acgpublishing.com/index.php/CCB/article/view/439 <p>Plants exposed to cadmium (Cd) stress have reduced growth, ineffective photosynthetic rate and poor ability to resist any other environmental calamity. In this study, we aimed to investigate the effect of Kn (kinetin) in alleviating Cd stress in mung plants. Plants of V. radiata were grown in soil contaminated with Cd (100 ppm Cd at 100 /Kg soil) for five days, and then Kn (10 µM) was aerially sprayed onto the leaves in a volume of 10 mL. The plants subjected to Cd stress alone had degraded growth conditions, with RGR, NAR, LAR and TPW reduced by 6.41 %, 59.22 %, 50 % and 6.20 % compared to the control. Interestingly, Kn, an application of synthetic cytokinin, improved growth conditions by 55 % in RGR, 30.12 % in NAR and 19.40 % in LAR and TPW 14 % compared to control. The underlying mechanism for growth enhancement by Kn was the induction of higher antioxidant activity. The Kn-treated seedlings had higher production of antioxidant enzymes such as peroxidase (POD) (50.87 %) and ascorbate peroxidase (APX) (32.61 %) and antioxidant secondary compounds such as TPC (59.21 %), TFC (26.35 %) and proline (28.07 %) compared to the control. This increase in antioxidant activities was due to the complementation of Kn with endogenous IAA (indole-3-acetic acid), GA4 (gibberellic acid) and tZ (trans-zeatin) in the seedlings as these were high in level (30.84 %, 19.21 %, and 35 % respectively) compared to the control. In contrast, these antioxidant activities were reduced in Cd stressed seedlings compared to the control and therefore growth was severely suppressed. Hence, the mechanism of Kn to induce antioxidant activity was due to complementation with endogenous IAA, GA4 and tZ for higher antioxidant response and growth enhancement.</p> Naveed Ali1, Muhammad Junaid Yousaf1*, Fawziah A. Al-Salmi2, Maha AlHarbi3, Amr Elkelish4, Siham M.AL-Balawi5, Aisha Siddique6, Fawad Ali6*, Imad Gul7, Abdul Manan8 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-16 2024-04-16 19 01 597 617 THE IMPACT OF COVID-19 ON PHARMACY SERVICES AND PATIENT CARE https://www.acgpublishing.com/index.php/CCB/article/view/828 <p>The emergence of the Covid-19 pandemic has significantly impacted healthcare systems worldwide, including pharmacy services and patient care. This essay explores the effects of Covid-19 on pharmacy services and other patient care services. Through a review of literature and analysis of data, this essay examines the changes in pharmacy services, medication management, patient interactions, and healthcare delivery due to the pandemic. The study highlights the challenges faced by pharmacies, the adoption of telehealth services, and the importance of implementing new strategies to ensure continued patient care during and post-pandemic.</p> <p><strong>Keywords</strong>: Covid-19, pharmacy services, patient care, medication management, telehealth, healthcare delivery</p> Mohammed Lafi Almutairi, Saleh Rshed Alrakaimi, Hamed Ramhan Almutairi, Salman Turki Alharbi Abdulelah Saud Almutairi, Afnan Mohammed Abdullah Alharbi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-23 2024-05-23 19 01 761 765 STUDYING THE EFFECT OF BENZENE ON THE LEVEL OF A NUMBER OF VARIABLES AND PERCENTAGE OF FATTY ACIDS FOR WORKERS IN GAS STATIONS IN MOSUL https://www.acgpublishing.com/index.php/CCB/article/view/848 <p>This study included the estimation of a number of biochemical variables related to antioxidants and the percentage of fatty acids. Glutathione(GSH), manoaldehyde (MDA), and the total capacity of antioxidants (TAC)in the blood serum of men who work at gas stations in the city of Mosul / Iraq. The workers were selected so that they did not suffer from any apparent disease (heart disease / diabetes / blood pressure) and were exposed on a daily basis to benzene and petroleum product pollutants, and the results of these variables were compared with a group of men of the same ages who do not work in the field of petroleum products. In this study, the percentage of fatty acids of different types (saturated and unsaturated) in the three parts of blood serum was measured: triglycerides(TG), phospholipids(PL), and cholesterol esters(CE). The results showed that there were significant differences in the level of biochemical variables and the percentage of fatty acids between the group of workers and the control group, which indicates the presence of an effect of gasoline and oil pollutants on the health of workers in this field.</p> <p><strong>&nbsp;</strong></p> <p><strong>Keywords: </strong>GSH, MDA,TAC, gasoline, fatty acids , gas stations</p> Noor A. Abd Al-Jabbar , Reem N. Alsawaf , Ebtehag Z. Sulyman Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-27 2024-06-27 19 01 1004 1012 BABY MASSAGE ASSISTANCE IMPROVES SLEEP QUALITY AND GROWTH OF LOW BIRTH WEIGHT BABIES IN SAMARINDA CITY https://www.acgpublishing.com/index.php/CCB/article/view/864 <p><strong>Introduction:</strong> Low birth weight (LBW) is defined as a birth weight of less than 2.5 kilograms regardless of the neonate's gestational age, according to the World Health Organization (WHO). Indonesia is in the highest ranking in Southeast Asia, with an LBW percentage of more than 9.9%, which amounts to around 450 thousand births annually (WHO, 2023). Research in Wuhan, China, shows that babies with LBW are at risk of experiencing delays in motor development. One of the factors that influence a baby's growth is sleep and rest. Baby massage is an intervention that involves stroking using different movements uniformly throughout the baby's body. Baby massages have many benefits, including increasing body weight. Other research also proves that babies who are massaged have regular sleep patterns. <strong>Method:</strong> This type of research is quantitative, with a Quasi-Experimental Nonequivalent Control Group Design. The sample consisted of 36 breastfeeding mothers divided into 2 groups: the intervention and the control groups. In this research, the experimental group was given baby massage assistance, and the control group was given education via Zoom. <strong>Results:</strong> There were differences in LBW babies' growth, improved sleep quality before and after baby massage assistance in the intervention group, and education via Zoom in the control group. Discussion: Various efforts have been made to increase growth in LBW babies, one of which is by assisting with baby massage. A massaged baby will feel comfortable so that the baby can sleep longer, and the quality of the baby's sleep will improve. Sleep quality has a vital role in the growth of LBW babies. Babies with good quality sleep according to age will significantly impact their growth and development. <strong>Conclusion: </strong>Baby massage assistance and education can improve sleep quality and influence LBW babies' growth in Samarida City.</p> Andi Lis Arming Gandini, Andi Ummu Salmah, A.Arsunan Arsin, Stang, Aminuddin Syam, Muhammad Tahir Abdullah, Syamsiar S. Russeng, Santi Martini Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-25 2024-07-25 19 01 1144 1155 EXOGENOUS MELATONIN ENHANCES CARCASS TRAITS, LITTER CONDITION, AND WELL-BEING OF BROILERS EXPOSED TO HEAT STRESS https://www.acgpublishing.com/index.php/CCB/article/view/881 <p>One of the main goals of producing broilers successfully is to maintain dry litter. Exposure to heat stress may be affected carcass traits and litter condition in poultry houses. This study was conducted to evaluate the using exogenous melatonin for elevate the negative effects of heat stress on carcass traits and litter for broiler chickens (Ross 308).&nbsp; 400-one day old broiler chicks were randomly split into five equal groups with four replicates, each with 20 chicks. The first group (C) fed on basal diet without melatonin and served as control. While the second (M1) and third (M2) groups received 10 and 20mg of melatonin / kg diet, respectively. And the 4<sup>th</sup> and 5<sup>th</sup> received 10 and 20mg of melatonin in drinking water / Liter, respectively. All birds were subjected to heat stress during the experimental period (1-35 d). Results indicated that carcass yield, breast, thigh and back percentages were significantly (P&lt;0.05) increased for birds received melatonin hormone compared with control. Feces weight was significantly (P&lt;0.05) decreased in birds received melatonin compared to the control group at the 2<sup>nd</sup>, 4<sup>th</sup> and 5<sup>th</sup> weeks of age. Data showed that using of melatonin significantly (P&lt;0.05) improved litter condition (moisture, pH and bacterial count) at heat stress. Also, adding melatonin significantly (P&lt;0.05) improved feather hygiene and decreased footpad dermatitis%. Finally, we can conclude that administration melatonin in diet or drinking water for heat-stressed broilers at levels 10 or 20mg significantly improved carcass traits, litter condition with beneficial effects on well-being of birds.</p> Mohammad A. Elsagheer, Mohammed Khalil Ibrahim Al-Saeedi, Hashim Hadi Al-Jebory , Rasha Fajer Al-Jebory, Mohamed R. Eletmany Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-13 2024-08-13 19 01 1306 1330 APPLYING THE GOOGLE EARTH ENGINE CLOUD COMPUTING PLATFORM IN ENVIRONMENTAL RESEARCH: FORECASTING FUTURE LAND USE AND LAND COVER MAP https://www.acgpublishing.com/index.php/CCB/article/view/902 <p>Hanoi City is Vietnam's cultural, political, and economic centre, where dense population and rapid urbanisation pose many challenges to planning effective land use and sustainability. The study used a real-time satellite image data set for land cover classification Dynamic World V1 data to analyse land cover changes for Hanoi city from 2018 to 2022 combined with high-resolution digital elevation data and using random forest algorithms to predict future land cover classification. The results show a significant increase in Crops and Built areas in the future and a substantial decrease in the city's agricultural land, trees, and bare land. The model has a reasonably high classification accuracy of about 74.2% and a Kappa coefficient of 0.6688. The research results have also shown the ability to apply cloud computing on the Google Earth Engine tool platform to forecast land use cover changes. This is a scientific basis that provides information to help managers come up with long-term strategies for sustainable urban development.</p> Yen Hai Hoang, Dong Phuong Nguyen, Hoa Thi Nguyen, Quoc Phi Nguyen, Ngoc Thi Tran Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-08 2024-09-08 19 01 1578 1585 PERSON-ENVIRONMENT FIT AND ITS DIMENSIONS AS PREDICTORS OF HYGIENE FACTORS AMONG THE CEBU INSTITUTE OF TECHNOLOGY-UNIVERSITY EMPLOYEES https://www.acgpublishing.com/index.php/CCB/article/view/921 <p>&nbsp;This study investigates the influence of Person-Environment Fit (PE Fit) on Hygiene Factors among the employees of Cebu Institute of Technology-University (CIT University) during the 2023 to 2024 academic year. Utilizing the Perceived Person-Environment Fit Scale (PPEFS) and Bellingham’s Job Satisfaction Survey, data was collected from 278 respondents through a descriptive predictive survey design.</p> <p>Findings suggest a predominantly positive alignment between employee perceptions and their work environment, with variations noted in Person-Supervisor Fit. While overall Hygiene Factors received high agreeability, areas for improvement were identified in Compensation, Benefits, and Personal (Work-life Balance). Notably, higher levels of P-E Fit correlated with increased satisfaction with Hygiene Factors, highlighting the importance of value alignment.</p> <p>The study emphasizes the significance of Person-Organization Fit and Person-Supervisor Fit in shaping employee satisfaction and recommends further research to explore demographic considerations. Recommendations include revamping communication channels, aligning organizational values, enhancing supervisor training, optimizing compensation and benefits, and promoting work-life balance initiatives to foster a supportive and fulfilling work environment at CIT University.</p> Florabel H. Chua and Ronald C. Yrog-irog Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-15 2024-10-15 19 01 1785 1814 USE OF CODED QR AS A MODEL CHANGING THE BEHAVIOR OF TRADERS AND BUYERS TRADITIONAL PEOPLE'S MARKET https://www.acgpublishing.com/index.php/CCB/article/view/201 <p>Each stakeholder must manage healthy environmental quality through their duties and functions to achieve a clean, safe, comfortable, and healthy People's Market. Implementing healthy behavior by traders, buyers, and visitors to public markets is one effective way to create and control healthy public markets. Pocketbooks, videos, and posters are integrated into QR codes. This media contains guidelines for healthy public markets and for clean and healthy living behavior, which is expected to help the public increase compliance in keeping markets clean and healthy. This research aims to find out the delivery mechanism, media either through QR barcodes or other easy methods for buyers, traders, and visitors to understand to change their behavior using a quantitative descriptive approach. The population in this study were market residents (traders and buyers/market visitors). The sample in this study used a quota sampling technique of 40 people, data collection using closed questionnaires, quantitative descriptive data analysis in the form of percentages, QR Barcode submission to change the behavior of participating market residents to keep the people's market healthy, QR Code on the banner via WhatsApp social media. Benner QR Barkot is installed at all gates; video media is the easiest to learn and takes 2-3 days. WhatsApp groups and direct discussions are expected to be an alternative for evaluating healthy people's market implementation.</p> 1*Darwis, 2Dihamri, 3Fikitri Marya Sari, 4Ade SisscaVillia Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-10 2024-02-10 19 01 140 148 EFFECT OF SOME MEDICINAL PLANTS ON LABORATORY ANIMALS EXPOSED TO ALUMINUM POISONING https://www.acgpublishing.com/index.php/CCB/article/view/302 <p>Aluminum is recognized as a public health concern because of its potential toxic effects on human health. Therefore, the current experiment was conducted to investigate the effectiveness of medicinal plants that include Cucurbita pepo and Ganoderma lucidum in reducing the toxicity induced by aluminum chloride (AlCl3) in animals. In this experimental study, thirty male rats were allocated to six groups. no treatment (control), AlCl3 (40 mg/kg B.W.), Cucurbita pepo, Ganoderma lucidum, Cucurbita pepo +AlCl3, Ganoderma lucidum+AlCl3, for 28 days.&nbsp; On the final day, animals were sacrificed, Indices of body weight, liver, kidney, spleen, blood component parameters, biochemical parameters of liver and kidney function, and antioxidants were estimated. AlCl3 treatment resulted in a significant decrease (P&gt;0.05) in the values of RBCs, HCB, HCT, MCV, MCH, MCHC, GRAN PLT and Glutathione. a significant increase in WBC, MON and liver, kidney, body weight, uric acid, Urea, Creatinine, ALT, AST, ALP and Malondialdehyde. There was no significant difference in LYM and Spleen weight compared with the control group. As for the groups of both Cucurbita pepo+ Aluminum chloride and Ganoderma lucidum+ Aluminum chloride led to a significant decrease in WBC, MON, uric acid, Urea, Creatinine, ALT, AST, ALP and Malondialdehyde. Increase in body weight, RBCs, HCB, HCT, MCV, MCH, MCHC, GRAN, PLT and Glutathione. No significant difference in Spleen weight and LYM comparison with the group infected with aluminum chloride poisoning. The present study concluded that Cucurbita pepo and Ganoderma lucidum had beneficial effects as they were able to reduce cadmium chloride toxicity in male rats.</p> <p>Key word: Cucurbita pepo, Ganoderma lucidum, aluminum chloride, haematological, Biochemical parameters.</p> Abd-Alhadi Ibrahim Hussein Al Jumaily1, Adnan Mohammed Ahmeed Aldulaimi1 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-26 2024-03-26 19 01 380 391 CAFFEINE ISOLATION AND CYTOTOXIC ACTIVITY OF CHLOROFORM FRACTION FROM ETHANOL EXTRACT OF DURIOKUTEJENSIS AGAINST T47D CELL LINE https://www.acgpublishing.com/index.php/CCB/article/view/810 <p><strong>Background and Aims</strong>: Approximately 19 of 28 species of durian were grown in Borneo. One of them, Duriokutejensis (<em>durian pulu</em>) have not been explored for its potential in anti-cancer treatments. This study aimed to isolate chemical compounds and to evaluate the cytotoxicity of the crude extract and isolated compounds from the chloroform fraction of durian pulu’s stem bark against breast cancer T47D cell line.</p> <p><strong>Methods</strong>: The extracts were screened for phytochemicals such as flavonoid, terpenoid, alkaloid, saponin, tannin, polyphenol, and anthraquinone. The vacuum liquid chromatography (VLC) technique was employed to extract fractionation. Isolation and purification were performed using Sephadex column chromatography. The structure of the pure compound was elucidated by spectroscopic analysis (1H NMR, 13C NMR, COSY, HMBC, and HMQC). The extract and isolated compound were tested against T47D by MTT assay. One compound, caffeine, was isolated from the chloroform fraction.</p> <p><strong>Result</strong>: The IC50 values of ethanol extract and caffeine of the stem bark were 331.82 and 361.59 µg/mL, respectively.</p> <p><strong>Conclusion</strong>: The findings showed that both the crude extract and its isolated compound have no potential of cytotoxic activity against breast cancer T47D cell line.</p> <p><strong>Keywords</strong>: Breast Cancer, Caffeine, Cytotoxic, DurioKutejensis, Phytochemical, T47D Cell Line</p> Amaliyah Dina Anggraeni, AghniaFuadatul Inayah, Haryoto Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-27 2024-04-27 19 01 665 674 “INVESTIGATING THE MECHANISMS AND GENETIC FACTORS INVOLVED IN THE MIGRATION AND NAVIGATION OF AVIAN SPECIES” https://www.acgpublishing.com/index.php/CCB/article/view/837 <p><strong><em>: Migration biology is an important chapter of the past decade which includes the wealth and health of descriptive articles that indicate different kinds of emigrational aspects. We must understand the proximate as well as ultimate causes of migration timing, energy distribution, optimized performance, immigration success, and fitness for the purpose of supporting wildlife population management as well as conservation initiatives by putting in place suitable safeguards or controlling environmental variables that affect migration. Different kinds of psychological measurements and dance are an important part by using new and innovative approaches and experimental processes. </em></strong></p> <p><strong><em>For hundreds of thousands of generations, humans have been intrigued by birds' extraordinary capacity to travel to faraway locations with accuracy. A unique combination of biological processes and genetic factors organizes this intricate accomplishment. The mechanism of Avi and species are divided into some parts like “Magneto reception”, “Landmark Recognition”, “Sun and Star Navigation”, and “Olfaction”. </em></strong></p> <p><strong><em>According to the sensory movement theory, which explains how homing pigeons navigate, birds learn how to connect directions from the wind with breeze-borne scents within their homes and, after being moved, calculate their home orientation based on ambient odors in the area around them. The “migratory movements” are determined mostly in the passerine birds which are mostly presumed as the cultural and social factors that play the largest role in the environmental system. </em></strong></p> <p><strong><em>Keywords: navigation, migration, sensory movement theory, Landmark Recognition, homing pigeons</em></strong></p> Parimala B., and Krishna Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-31 2024-05-31 19 01 849 863 PHARMACOLOGICAL EVALUATION OF ANTIDEPRESSANT ACTIVITY OF THE ETHANOLIC EXTRACT OF BOMBAX CEIBA FLOWERS IN ALBINO WISTAR RATS https://www.acgpublishing.com/index.php/CCB/article/view/855 <p>A significant segment of the worldwide population experiences depression, a prevalent mental health issue. Plant extracts are among all Organic compounds gained attention interest due to their possible antidepressant properties. The study's objective is to analyse whether an ethanolic extract of <em>Bombax ceiba</em> flowers exhibits antidepressant effects on Albino Wistar rats. Thirty Swiss Albino Wistar rats were divided into five groups, with each group containing six rats, and the study lasted for 42 days. We study three doses of the flower extract of <em>B. ceiba</em> (100, 200, 400mg/kg) the effects of both acute and chronic depression were evaluated using two models: the Porsolt forced swim test and the tail suspension test. In the acute trial, drugs (test drug, standard control, and vehicle) were given orally one hour prior to the experiment, and in the chronic research, the drugs were given daily for 14 days. The force swim test and tail suspension test were used in both acute and chronic investigations to show that imipramine had strong antidepressant action. This was evidenced by a decrease in the period of immobility. <em>B. ceiba</em> had antidepressant effect that was dose dependant. The antidepressant effect of <em>B. ceiba</em> 100 mg/kg was only evident in the acute force swim test. In the force swim test (both acute and chronic), <em>B. ceiba</em> 200 mg/kg showed antidepressant action; however, it did not show any effect in the tail suspension test. In investigations conducted on both acute and chronic patients, <em>B. ceiba</em> 400 mg/kg demonstrated maximum antidepressant effect that was comparable to that of imipramine, a prescription medication. <em>B. ceiba</em> showed dose dependent antidepressant action with BC-400mg/kg showing maximum effect.</p> Aarti Sati , Ankita Tomar, Deepti Negi, Suneha Rani , Priyanka Bhandari Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-16 2024-07-16 19 01 1044 1058 INHIBITION OF HERPES SIMPLEX VIRUS AND VESICULAR STOMATITIS VIRUS PROLIFERATION BY LACTIPLANTIBACILLUS PLANTERUM AND STAR ANISE EXTRACT IS ASSOCIATED WITH INDUCTION OF MX GENE EXPRESSION https://www.acgpublishing.com/index.php/CCB/article/view/871 <p><strong>Purpose: </strong>There is an immense need to develop new antiviral compounds that are effective and have little side effects. Natural compounds provide a good candidate that is gaining popularity. Probiotics as <em>Lactiplantibacillus plantarum</em> and plant-derived medicines as star anise extract have been investigated to treat viral diseases, cancer, and inflammation. This work aimed to investigate the antiviral effect of probiotics (<em>Lactiplantibacillus plantarum</em>) and (star anise) against Herpes simplex virus type 1(HSV-1) and Vesicular stomatitis virus (VSV).</p> <p><strong>Patients and methods: </strong><em>Lactiplantibacillus plantarum</em> and star anise extract had been prepared and tested against vero cell lines for cytotoxicity assay. The antiviral effect of <em>L. plantarum </em>and star anise against HSV-1 and VSV was evaluated by titration calculation (TCID50). The expression of <em>MX</em> genes were measured in infected cells before and after treatment with <em>L. plantarum </em>and star anise.</p> <p><strong>Results: </strong>We found that <em>L. planterum</em> is more effective against <em>HSV-1</em> and caused 2.5 log reduction in virus titre while star anise extract is more effective against VSV and caused 1.25 log reduction in virus titre. Evaluation of <em>MX</em> genes expression revealed higher expression in HSV-1 infected cell treated with <em>L. planterum</em> and VSV infected cells treated with star anise extract.</p> <p><strong>Conclusion: </strong><em>L. planterum</em> and star anise could be useful antiviral natural compounds that have minimal side effects</p> Dalia Elebeedy, Asmaa Sayed Abdelgeliel, Aml Ghanem, Ingy Badawy Bayan H. Sajer, Alya Redhwan, Mashail A Alghamdi, Mohamed R. Eletmany, Marwa El-Sayed Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-05 2024-08-05 19 01 1247 1256 HEALTH KNOWLEDGE ON CHILD-REARING PRACTICES OF MOTHERS IN BARANGAY CALAMBA, CEBU CITY, PHILIPPINES https://www.acgpublishing.com/index.php/CCB/article/view/890 <p><strong><em>&nbsp;</em></strong>The purpose of this study is to determine the demographic profile of the mothers, their level of health knowledge on child-rearing practices and whether there is a correlation between the demographic profile and health knowledge on child-rearing practices, including feeding practices, hygiene practices and care of the sick practices. Thus, the paper was to ascertain the link between these factors Mothers in Barangay Calamba, Cebu City, (N = 239) were asked to complete a questionnaire on demographic profile and level of health knowledge on child-rearing practices. The present study investigated on the contextual gap based on factors that affect parenting effectiveness on strategies to strengthen parenting capacity. The questionnaire consists of closed-ended questions, which means that respondents select their answers from a predetermined list of options. A form comprising closed-ended questions. through the use of descriptive and inferential statistics (Chi-square test).. The study's result revealed that most mothers in Barangay Calamba, Cebu City were adults aged 30-39 years old and have reached College level. Although the majority of the mothers were Christian Catholics, as findings showed there was no significant correlation between religion and their health knowledge on child-rearing practices. Overall, maternal education, age, monthly income, and number of births were significantly related to health knowledge on child-rearing practices. These findings provided valuable insights into the factors influencing maternal decision-making regarding child health and well-being.</p> Grace C. Arcamo, Luisa C. Aton Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-21 2024-08-21 19 01 1479 1787 ASSESSING COMPUTER SKILLS OF INMATES AT BJMP CITY OF NAGA: FOUNDATION FOR AN EXTENSION PROJECT https://www.acgpublishing.com/index.php/CCB/article/view/910 <p>This study evaluates the computer system servicing skills of Persons Deprived of Liberty (PDLs) at the Bureau of Jail Management and Penology (BJMP) in Naga City, Cebu, as the basis for a proposed extension program. Using a descriptive-evaluative research design, the study surveyed 25 PDLs nearing release. The results, analyzed through mean distribution, revealed low proficiency across all assessed competencies. Basic skills, such as hardware assembly and operating system installation, had an average weighted mean of 2.52, while networking tasks scored the lowest with a mean of 1.85. Office productivity software and Google Suite proficiency were similarly low, with means of 2.35 and 2.58, respectively. These findings highlight a substantial skills gap, suggesting the need for targeted ICT training. The proposed extension program should focus on practical skill development, software proficiency training, and certification to enhance PDLs’ employability and support their reintegration into society. Addressing these skill deficiencies is crucial for reducing recidivism and increasing post-release opportunities for PDLs.</p> Glenn A. Trinidad Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-16 2024-09-16 19 01 1668 1673 MANGROVE SPECIES DIVERSITY IN ARIYANKUPPAM ESTUARY, PUDUCHERRY, INDIA https://www.acgpublishing.com/index.php/CCB/article/view/172 <p>True mangrove species and associate mangrove species are the two categories into which the plant life in a mangrove habitat is divided. While associated species are present in both the mangrove ecosystem and its environs, true mangrove species are exclusively found in mangrove wetlands. There are 69 plant species recognized to be true mangroves worldwide. The present study aim to find out the true mangrove diversity in Ariyamkuppam, Puducherry. Six true mangrove floral species from three families, three orders, and the same class were recorded. One true mangrove was threatened Species in IUCN Red data book.</p> Silpa.P & Dr.T. Ramanathan* Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-26 2024-01-26 19 01 32 38 THE CONTINUATION OF THE COCONUT PRODUCT COOPERATIVE IN NORTH MALUKU PROVINCE, INDONESIA https://www.acgpublishing.com/index.php/CCB/article/view/281 <p>The coconut plant, long known to the people of Indonesia, is widespread throughout the<br />archipelago. As a strategic commodity, coconut plays a crucial role in the social, cultural, and<br />economic aspects of Indonesian society. Coconut production in Indonesia reaches 18.3 million<br />tons, making it the highest in the world. This research aims to analyze the condition of sustainable<br />livelihood assets within coconut processed product cooperatives using the pentagon model. Data<br />collection involves average asset values based on categories such as Human Capital, Natural<br />Capital, Financial Capital, Social Capital, Physical Capital, Entrepreneurship Capital, and Political<br />Capital. The analysis results show variations in the average asset values, with Physical Capital and<br />Entrepreneurship Capital having the highest values, while Political Capital has the lowest. This<br />indicates that coconut processed product cooperatives excel in physical, financial, and<br />entrepreneurial aspects, while also strengthening political support and social capital.<br />Keywords: Sustainable Livelihood, Coconut Commodity</p> 1Munawir Muhammad, 2Djoko Koestioni, 3Syafrial, 4Riyanti Isaskar Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-08 2024-03-08 19 01 243 257 STUDIES ON THE EFFECTS OF FAT-SOLUBLE VITAMINS E AND K ON THE GROWTH PERFORMANCE AND ANTIOXIDANT ACTIVITY OF LABEO ROHITA https://www.acgpublishing.com/index.php/CCB/article/view/335 <p>An experiment was conducted to find the effects of fat-soluble vitamins E and K on growth performance and antioxidant activity of Labeo rohita (Rohu). There were five treatments, T1 (control treatment) containing 0 mg/kg of vitamin E and K, T2, T3, T4, and T5 (Experimental treatment) containing 200 mg/kg of vitamin E, 500 mg/kg of vitamin E, 200 mg/kg vitamin K and 500 mg/kg vitamin K respectively in diets. Acclimatized Labeo rohita juveniles were transferred to the fisheries research farm of the University of Agriculture Faisalabad and fed twice a day for an experimental duration of six months. Physio-chemical parameters like temperature, dissolved oxygen (DO), pH, total hardness, electrical conductivity, etc. were maintained at their optimum level. Juveniles of Labeo rohita attained maximum growth during the thorough experimental period except in December due to abrupt environmental changes. Experimental treatment T3 (Vitamin E=500 mg/kg) showed maximum weight, fork, and total length that is 11.26g, 2.53cm, and 2.96 cm respectively. At higher concentrations of vitamin E in diet feed intake, feed conversion ratio (FCR) and specific growth rate (SGR) were also increased. Catalase (CAT) and peroxidase (POX) activity increased while superoxide dismutase (SOD) activity was slowed by high vitamin E concentrations supplemented diets in Labeo rohita. In T3 highest catalase activity (134.03U/ml) and peroxidase activity (0.34U/ml) were observed while the highest (SOD) activity (18.01U/ml) was observed in T1. A significant fluctuation (p≤0.01) in the growth and antioxidant activity of Labeo rohita was determined by statistical analysis during the whole experimental period.</p> Dr Amara Akhtar1, Muhammad Munawar Ramzan1, Misbah tasleem1, Amina zafar1, Nimra Naseer1, Mariam khalid1, Muntah tariq1, Musfira jabeen1, Misha Khalid1, Muhammad Ahmed Saqib1 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-06 2024-04-06 19 01 457 467 WATER POLICIES AND FARMERS VULNERABILITY IN GROUNDWATER IRRIGATION SYSTEMS https://www.acgpublishing.com/index.php/CCB/article/view/437 <p>Throughout most dry and dry parts of worldwide, increased rivalry to supplies of water is turning into an interpersonal, financial, and conservation problem. It's a significant issue in additional dry nations in Europe (such as Spain), the African continent (South Africa, Namibia, and Botswana), and other parts of the world where water consumption, habitat loss, and lack of water are all becoming socially concerning. While social anxieties about the national allocation of water ownership and ecological problems steadily develop in such nations, water challenges and local rivalries to water begin to take center stage on legislative plans and discussions in society. Groundwater supplies, that are becoming scarcer in a lot of cities worldwide, are becoming increasingly important to producers and the numerous businesses that rely on their crops. From cultivating foods that use fewer resources or using the best methods of irrigation, farmers may lower the amount of water they use. Their decisions may have far-reaching effects on farms. The effects and repercussions of excessive water limitations are examined in this paper across particular fields. Together with those involved in agriculture in so many nations, the examination was completed. Financial and technological analyses of the methods and modifications made by growers and daily consumers of water have been carried out in order to address the limited supply of the resource. Interactive seminars emphasized the relationships across owners within a particular category and also among distinct industries by bringing together various operators who may end up competing for an identical asset.</p> <p><strong>Key words</strong>: irrigation, water policies, vulnerability assessment, sustainable crops.</p> Fabrice Paulin Ketchagmen Fosso, Gozen Elkiran Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-16 2024-04-16 19 01 545 565 THE EFFECTIVENESS OF THE SELF-MANAGEMENT HYPERTENSION (SMH) APPLICATION IN INCREASING KNOWLEDGE AND SELF-EFFICACY OF THE ELDERLY WITH HYPERTENSION IN MAKASSAR CITY https://www.acgpublishing.com/index.php/CCB/article/view/826 <p>Poor knowledge and low compliance of the elderly with hypertension (HT) in terms of self-care, such as low adherence to medication, not maintaining diet, weight management, and physical activity, require different strategies in designing health education for the elderly with HT. A critical component in predicting self-care behavior is self-efficacy, which refers to people's beliefs about their ability to perform at a certain level of performance and includes a person's confidence to do an excellent job of self-care (Bandura, 1983). The effect of the application on improving the literacy and self-efficacy of the elderly with HT in terms of self-care of HT disease has been proven effective based on several research results in the world.</p> <p><strong>Research Objective</strong>: This study aims to see the effectiveness of SMH applications in increasing the knowledge and self-efficacy of elderly patients with HT.</p> <p><strong>Method</strong>: This study used <em>a quasi-experimental</em> design with <em>a pre and post-test control group design</em>. Samples of 80 older adults with HT in the treatment group and 40 elderly samples with HT were given therapy using the SMH application accompanied by an application use module. In the control group, 40 elderly samples with HT were given health education about self-management plus pocketbooks.</p> <p><strong>Results: </strong>Wilcoxon test results showed significant differences in knowledge before and after treatment in both the control and intervention groups and self-efficacy<em>(p&lt;0.05).</em> Changes in pre- to post-test scores mainly increased (98%) in the control group, while in the intervention group, all elderly (100%) experienced increased knowledge and self-efficacy.</p> <p><strong>Conclusion</strong>: SMH application-based interventions effectively increase knowledge and self-efficacy in the elderly with hypertension.</p> <p>&nbsp;</p> <p><strong>Keywords: </strong>Effectiveness, SMH Application, Knowledge, Self-Efficacy, Elderly with Hypertension</p> Hilda Harun, Ridwan Amiruddin, A. Arsunan Arsin, Abdul Salam, Mondastri Korib Sudaryo, H. Muh. Syafar, A. Ummu Salmah, Sudirman Natsir Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-18 2024-05-18 19 01 731 745 IMPULSIVE BUYING IN CIREBON TEENAGERS TRIGGERED BY EMOTIONAL COPING BEHAVIOR https://www.acgpublishing.com/index.php/CCB/article/view/846 <p>This research is motivated by the increasingly advanced e-commerce in today's digital world, becoming the main influence on teenagers' shopping patterns which causes the growth of more dominant consumer behavior. So that today's teenagers do not tend to prioritize secondary needs in their daily lives. The aim of this research is to analyze how much influence teenagers' emotional behavior has on impulsive purchases which cannot be separated from the spotlight on lifestyle and existence. The research was used using quantitative research methods, the Slovin formula and alternative data collection using a questionnaire with a total of 100 respondents (41 male respondents and 59 female respondents). The results prove that price discounts in e-commerce have a positive effect on impulse buying among teenagers in Cirebon. From the final observation results, it can be seen that the data collected shows that the number of online impulsive purchases among teenagers in Cirebon is very high, this can be seen from the answers to the attached questionnaire. The results of the data show that teenagers who make the most impulsive purchases are women for the reason of shopping because there are flash sales at certain events.</p> <p>&nbsp;</p> <p><strong>Keywords</strong>: Impulsive; Shopping; Lifestyle; E-Commerce</p> Raden Putri Zalfaa Faadhilah Taqiy , Shopa Shopiatul Fitria , Widya Septiani , Devita Aqilla , Farida Nurfalah , Dedet Erawati Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-25 2024-06-25 19 01 970 982 DEVELOPING NEW TECHNIQUES FOR DIAGNOSING INFECTIOUS DISEASES https://www.acgpublishing.com/index.php/CCB/article/view/862 <p>Infectious diseases continue to pose a significant threat to public health worldwide, with emerging pathogens and antibiotic resistance contributing to the complexity of diagnosing and treating these conditions. Developing new techniques for diagnosing infectious diseases is crucial in order to improve patient outcomes, prevent the spread of infections, and optimize treatment strategies. This essay explores the importance of developing new diagnostic techniques for infectious diseases at the Master level, highlighting the methodologies, results, and implications of such advancements. By leveraging innovative technologies and strategies, healthcare professionals can better identify and manage infectious diseases, ultimately leading to a healthier global population.</p> Mansour Nasser Almansour, Yazeed Abdullah Alfalah, Amal Mashaan jehad Alshammari Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2022-09-05 2022-09-05 19 01 4678 4683 PARAMEDICS ARE COLLABORATING WITH HEALTHCARE PROVIDERS TO OFFER MOBILE INTEGRATED HEALTHCARE SERVICES https://www.acgpublishing.com/index.php/CCB/article/view/879 <p>This essay explores the growing trend of paramedics collaborating with healthcare providers to offer mobile integrated healthcare services at the Master level. The essay discusses the rationale for this collaboration, the methodology used to implement these services, the results achieved, and the implications for the future of healthcare delivery. Additionally, the essay highlights the importance of this collaboration in providing more comprehensive care to patients and improving overall health outcomes.</p> Abdullah Ali Abdullah Alsahli, Ibrahim Saeed Mohammed Alahmari, Omar Abdulaziz Hamed Alghamdi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-13 2024-08-13 19 01 1416 1420 IMPACT OF PLANT-BASED DIETARY FAT LEVELS ON GROWTH, FEED UTILIZATION, BODY COMPOSITION, AND SERUM METABOLITES IN LABEO ROHITA https://www.acgpublishing.com/index.php/CCB/article/view/900 <p>Fish is the preferred and the cheapest source of high-quality animal protein for humans. The study aimed to assess the influence of varying levels of plant dietary fats on the growth, feed utilization, body composition, and serum metabolites of <em>Labeo rohita</em>, a significant carp species known for its rapid growth and palatable flesh. Seventeen fingerlings were acclimatized and subjected to six different dietary treatments, including mono- and polyunsaturated fat supplements at 3%, 6%, and 9%. Serum metabolites were analyzed using the Biuret assay for total serum proteins, glucose peroxidase method for total serum glucose, cholesterol oxidase-phenol amino phenazone method for total serum cholesterol, and GPO/PAP method for serum triglycerides. Physiochemical parameters were meticulously maintained throughout the trial period. The results revealed that fish fed with 6% polyunsaturated and 9% monounsaturated fat exhibited significantly higher feed utilization and maximum growth performance, particularly in treatments 3 and 5. Furthermore, significant alterations in body composition and serum metabolites, such as proteins, triglycerides, and cholesterol, were observed in these treatments. The study concluded that 6% polyunsaturated fats (soybean + sunflower oil) and 9% monounsaturated fats (canola + olive oil) could effectively enhance the growth of <em>Labeo rohita</em>. Statistical analysis was executed using analysis of variance (ANOVA) and under central registration depositary (CRD). These findings offer valuable insights into optimizing the dietary requirements for the growth and health of <em>Labeo rohita</em>.</p> Amara Akhtar, Ayesha Yaseen, Khadija Bareera, Saira Kanwal, Maniha, Umme Habiba, Muhammad Ahmed Saqib Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-07 2024-09-07 19 01 1560 1577 Oncoplastic Volume Displacement Techniques for Breast Conserving Surgery in Patients with Breast Cancer https://www.acgpublishing.com/index.php/CCB/article/view/919 <p>Breast cancer is the most common cancer in women, responsible for over 10% of new cancer cases annually and is the second leading cause of cancer death among women worldwide. The breast, consisting of 15-20 lobes and fat that determines size and shape, produces milk in response to hormones. Breast cancer often develops silently (Sathish Kumar, 2018), and is frequently detected through routine screenings or symptoms such as lumps, shape changes, or nipple discharge. Diagnosis requires physical exams, mammography, and biopsy, with early detection significantly improving survival. The cancer can spread via lymphatic and blood systems, leading to metastasis and a poor prognosis, underscoring the need for screening programs (Mahvi, et al. 2018).</p> Hamdy Mohamed Hussein, Omar Farouk Ali, Mohammed Ahmed Omar, Hamdy Hamed Mousa Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-11-09 2024-11-09 19 01 1955 1961 MODULATORY EFFECT OF PTEROSTILBENE ON TAIL TENDON COLLAGEN IN TYPE 2 DIABETIC RATS https://www.acgpublishing.com/index.php/CCB/article/view/198 <p>Introduction: The research was determined to investigate on the effects of pterostilbene and tetrahydrocurcumin (THC) on the collagen content and its physical and chemical characteristics in the tail tendon of streptozotocin (STZ) induced diabetic rats.</p> <p>Purpose:&nbsp; Ptrerostilbene and THC has been tested clinically and found to be effective in non-insulin dependent diabetes mellitus patients.</p> <p>Experimental design:&nbsp; In the experiment, a total of 24 rats (18 diabetic surviving rats, 6 normal rats) were used.&nbsp; The rats were divided into four groups of six each, after the induction of STZ diabetes.&nbsp; The experimental period was 45 days. Group 1: Normal rats. Group 2: Diabetic control rats. Group 3: Diabetic rats treated with THC (80 mg/kg body weight) in aqueous suspension daily using an intragastric tube for 45 days. Group 4: Diabetic rats treated with pterostilbene (40 mg/kg body weight) in aqueous suspension daily using an intragastric tube for 45 days</p> <p>Results: In the case of diabetic rats treated with pterostilbene and THC, the collagen content was significantly decreased.&nbsp; The extent of glycation, cross-linking and collagen linked fluorescence were significantly reduced.&nbsp; In addition to that, the collagen content in the  region as well as in the high molecular weight region in tail tendon was near normal when compared to diabetic control groups.&nbsp; The reduction in the advanced glycation and cross-linking of collagen in pterostilbene and THC treated rats to their antiperoxidative activity directly influence the collagen cross-linking and advanced glycation end products formation.</p> <p>Conclusion: The administration of pterosilbene and THC had a positive influence on the content of collagen and its properties in streptozotocin and nicotinamide diabetic rats. The pterosilbene administration was found to be more effective than THC.</p> <p><strong>Keywords:</strong> tetrahydrocurcumin, pterostilbene, collagen, streptozotocin, nicotinamide, blood glucose, plasma insulin</p> Pidaran Murugan1*, Sivaprakasam Maneemegalai2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-06 2024-02-06 19 01 111 125 A QUALITATIVE STUDY TO EXPLORE KNOWLEDGE, ATTITUDES AND DIETARY BEHAVIOR IN PREVENTING NUTRITIONAL PROBLEMS DURING PREGNANCY https://www.acgpublishing.com/index.php/CCB/article/view/298 <p>Anemia during pregnancy is a condition where hemoglobin levels are below 11 gr/dL during pregnancy. In Indonesia, one in two pregnant women experiences anemia. This is exacerbated by the occurrence of chronic energy deficiency during pregnancy. Conditions of anemia and chronic energy deficiency that continue during pregnancy will cause various health problems including the health of the fetus in the womb, even after birth, which has less than optimal growth and development. This research aims to identify determinant factors in preconception nutrition education and develop a framework for preconception nutrition education modules to prevent anemia and chronic energy deficiency during pregnancy. This research method is qualitative by conducting in-depth interviews with pregnant women, women in reproductive health, and health workers which location in Depok City, Indonesia. Data analysis uses thematic analysis. The results show how the importance of education for prospective brides regarding pre-conception nutritional preparation is provided by including elements of ideal pregnancy indicators, balanced nutritious food, and ways to prevent anemia and chronic low energy. The aim of preparing the module was to increase knowledge about healthy pregnancy and avoid nutritional problems, have an attitude that supports nutritional fulfillment and a healthy lifestyle, and have good dietary behavior, especially in regulating food intake. A digital educational media prototype has been created at the following link http://edukasiprakonsepsi.biz.id/Aplikasi_Catin/. The suggestion from this research is that health facilities need to give education about the pre-conception nutritional use of media to make it easier to access information repeatedly.</p> <p><strong>Keywords:</strong> Education; Pre Conception; Anemia</p> Ratna Wulandari1, *Ahmad Syafiq2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-21 2024-03-21 19 01 334 344 PROTECTIVE ROLE OF SPIRULINA ON HEMATOLOGY AND HEPATOTOXICITY INDUCED BY CUSO4 AND CUO NANOPARTICLES IN OREOCHROMIS NILOTICUS https://www.acgpublishing.com/index.php/CCB/article/view/716 <p>Copper toxicity poses significant risks to fish. <em>Spirulina platensis</em> a cyanobacterium (protist), has shown protective properties against metal-induced toxicity in various species. This study investigated the prophylactic role of <em>Spirulina platensis</em> in Nile tilapia (<em>Oreochromis niloticus</em>) against the toxicity of copper sulfate (CuSO₄) and Copper oxide nanoparticles (CuO-NPs). Over 15 days, tilapia were divided into five groups: For this purpose, fish were divided into five treatments. T<sub>0</sub> was a controlled treatment. T<sub>1</sub> was treated with 15mgl<sup>-1</sup> CuO-NPs. T<sub>2</sub> was fed with 2.5gkg<sup>-1</sup> Spirulina and 15mgl<sup>-1</sup> CuO-NPs. T<sub>3</sub> was treated with 15mgl<sup>-1</sup> CuSO<sub>4</sub>. T<sub>4</sub> was treated with 2.5gkg<sup>-1</sup> Spirulina and exposed to 15mgl<sup>-1</sup> CuSO<sub>4</sub>. CuSO<sub>4</sub> and CuO-NPs were given for the last 15 days and Spirulina was given on the first day of the trial in T<sub>2</sub> and T<sub>4</sub>. The results showed that both CuSO₄ and CuO-NPs significantly increased biochemical parameters like total ALP, ALT and AST. Hematological disturbances and erythrocyte count along with histopathological damage to organs like the liver were also observed. However, Spirulina supplementation notably mitigated these adverse effects, reducing and preserving tissue integrity and normalizing all parameters. This study highlights the species-specific protective effects of the agent and suggests that Spirulina may offer protection against copper-induced toxicity. Future research is needed to explore the long-term impacts and underlying mechanisms of these agents, along with their optimal dosages for enhancing fish health in aquaculture.</p> Rasheeka Rasheed, Amara Akhtar, Rohma Talha, Babar Khan, Rabeel Mehmood, Awais Amin, Mubeen Sabir, Muhammad Ahmed Saqib Copyright (c) 2022 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-30 2024-10-30 19 01 1930 1946 REPORT OF A RARE CASE OF TYPE I NEUROFIBROMATOSIS IN A FEMALE PATIENT IN RIYADH, SAUDI ARABIA. https://www.acgpublishing.com/index.php/CCB/article/view/835 <p>Neurofibromatosis type 1 (NF-1), which is sometimes called von Recklinghausen's disease, is a rare genetic trait that causes many neurofibromas to form on the skin and nerves. These are harmless lumps. Most neurofibromas in the head and neck are found in soft tissues. We talk about a case of NF-1 in a 53-year-old Saudi woman in this report. During childhood, numerous darkly pigmented macules appeared on the epidermis, indicating the onset of the disease. The patient had pervasive freckling and café au lait spots on her body, as well as a diffuse, approximately 4 cm 3 cm swelling. Notably, large masses extending from her left ear to her left orbit were observed on her visage. These aggregates were distinct, painless, and mobile. On the margins, dorsum, and central border of the tongue, there were numerous exophytic lesions.The patient's diagnosis of NF-1 was confirmed based on the fulfillment of two or more diagnostic criteria established by the National Institute of Health Consensus Development Conference. Following a thorough surgical ablation, no recurrence was detected during the 15-month follow-up period.</p> <p><strong>Key Words</strong>: Neurofibromatosis 1, Soft tissue, Neurofibromas, Case report.</p> Fatima Yahya ALBishry1, Hadeel Saad2, Nawaf Alotaibi3, Fahad Alnafisah4, Al Hanouf Al Assiri5 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-29 2024-05-29 19 01 818 830 BOOK REVIEW: ACADEMIC REVIEW FOR “ANALYTICAL CHEMISTRY” BOOK https://www.acgpublishing.com/index.php/CCB/article/view/853 <p>This study aims to review the Arabic book “Analytical Chemistry” written by Dr. Abdullah Mahmoud Abu Al-Kabash, a Professor of Analytical Chemistry at King Fahd University of Petroleum and Minerals, published by Al-Obaikat Publishing House in 2012. To achieve the objectives, the researcher deeply read the book, considering its title of the book, the author, the introduction, and the chapters of the book, etc. Using descriptive and critical methods, the book’s evaluation is briefly written, highlighting the strongest and weakness. Finally, based on book review, several recommendations and further suggestions are provided.</p> Abdallah M. Alshhab , Mamoon M. Alokour Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-12 2024-07-12 19 01 1036 1039 IMPROVING POSYANDU SERVICE PERFORMANCE THROUGH THE USE OF SMARTPHONE APPLICATIONS: LITERATURE REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/869 <p><strong>Introduction: </strong>Posyandu, or Integrated Service Post, is the government's effort to make maternal and child health services more accessible to Indonesians. This literature review aims to identify and describe the performance of posyandu services using smartphone applications,</p> <p><strong>Method: </strong>The research method is a systematic review using techniques such as PICOT and journal search terms via MESH. The literature sources in this study mostly come from online journal databases that provide Indonesian and English journal articles in PDF format, such as Pubmed, Proquest, Google Scholar, and ScienceDirect, as well as other sources, such as books. Researchers wrote keywords according to MESH (Medical Subject Heading), namely "service", "smartphone", and "posyandu," and selected full text.</p> <p><strong>Research result: </strong>Of the 120 journals that reviewed the abstracts, there are 20 journals consisting of review journals and journals related to the use of smartphones in posyandu services. So, the 10 remaining journals will be read in full-text</p> <p><strong>Discussion:</strong> Smartphones are modern technological devices that make it easier to communicate, obtain information, and do work quickly and comprehensively. The use of smartphones in the world of health is considered effective in increasing access to health services, especially posyandu services.</p> <p><strong>Conclusion: </strong>The use of smartphones and applications in posyandu services accelerates the achievement of targets in the form of posyandu and is effective in increasing access to health services.</p> Tanwir Djafar , Sukri Palutturi, Andi Zulkifli, Anwar Mallongi, Ida Leida, Suriah Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-02 2024-08-02 19 01 1214 1228 THE ROLE OF EXTERNAL VOLUME EXPANTION AND CELL ASSISTED LIPOGRAFTING IN IMPROVING POST BURN SCAR QUALITY, A RANDOMIZED CLINICAL STUDY https://www.acgpublishing.com/index.php/CCB/article/view/888 <p>Throughout history, scars have represented a problem, where most of the solutions are unsatisfactory. The search for a more successful method with long‑term, better results for different skin types remains the main challenge facing plastic surgeons. External volume expansion (EVE) devices mechanically stretch and stimulate tissues by suction in a non‑invasive manner. Stretch releases the skin and it has been postulated by different studies that the mechanism of action could be direct mechanical action on individual cells, induction of ischemia, inflammation and soluble mediators which stimulates cell proliferation, adipogenesis and, most importantly, vascular remodeling.. Platelet-rich plasma (PRP) is an autologous blood-derived product enriched in platelets, growth factors and chemo/cytokines delivered in a concentrated volume of plasma. PRP has the potential to deliver a high concentration of growth factors to target tissues by virtue of the contents within the alpha and dense granules. A relatively new option for the treatment of scar tissue is the use of autologous fat grafting, first described by Neuber in 1893 and later refined by Coleman. Autologous fat grafting has a volume‑increasing effect and is thought to stimulate the neosynthesis of collagen fibers, which therefore increases dermal thickness, resulting in an improvement in skin quality. The use of autologous fat grafting has increased in common practice, but to date there is a lack of scientific evidence regarding the effects on scar tissue. Fat grafting for soft tissue defects and volume expansion presents an appealing alternative or adjunct to reconstruction with flaps or implants because of its simplicity of technique and low morbidity associated with it. However, the unpredictable survival (30%–80%) and the inverse correlation of survival to injection volume have led to skepticism about its utility.</p> Hesham Abdelmoniem Eissa, Khaled Mohammed Hassan, Ahmed Adel Nor El Den, Ahmed Mahrous Mohamed Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-20 2024-08-20 19 01 1466 1469 INSTRUCTIONAL MODEL COACHING FOR NURSING STUDENTS: GUIDELINES FOR SIMULATION https://www.acgpublishing.com/index.php/CCB/article/view/908 <p><strong>Abstract</strong>: <em>The study assessed the Instructional Model Coaching for various procedures and identified special areas for the Bachelor of Science in Nursing program. The assessment focused on several areas, including the profile of the respondents in relation to specific variables, namely: the clinical instructor's evaluation of the level of competency of BSN students undergoing pre-clinical simulation and actual practice, as well as the clinical practice involving human-patient simulators. The performance of BSN students in nursing procedures was also evaluated based on semi-structured assessments. The study utilized the descriptive correlational method. Moreover, the findings revealed that among the four areas of assignment, the Delivery Room, with 7-10 years of experience, had the highest number of periods supervising BSN students compared to the other areas. Most respondents attended orientation programs that enabled them to manipulate models and utilize updated electronic instructional materials. These programs, which included training in effective and suitable simulated environments, allowed them to conduct demonstrations for assigned groups of BSN students and to implement return training programs using instructional models. A noticeable difference was observed among BSN students in their nursing procedures during pre-clinical simulations, with better performance observed during actual clinical field practice. In addition, there is a significant relationship between the level of competence and the actual performance of the students. In conclusion, the assessment of clinical performance after exposure to simulation using a human-patient simulator showed that BSN students, as noted by the clinical instructors (respondents), achieved an almost perfect execution of nursing procedures.</em></p> Grace C. Arcamo, Jason R. Lim, and Jeanette P. Lim Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-12 2024-09-12 19 01 1653 1658 CHARACTERISTICS OF PATIENTS WITH PANIC DISORDERS P THERE IS HYPERTHYROIDISM ACCOMPANIED BY TONSIL HYPERTROPHY AND THYROID EYE DISEASE WITH ECG PICTURE SICK DYSFUNCTION NODE https://www.acgpublishing.com/index.php/CCB/article/view/168 <p>Background: Hyperthyroidism is an endocrine disorder with the second highest incidence rate after diabetes, and Graves' disease is the most common cause of hyperthyroidism. Objective: To determine the characteristics of patients with panic disorder in hyperthyroidism with an ECG picture of sick node dysfunction. Methods: This study is a Systematic Review using the Preferred Reporting Items for Systematic Reviews and Meta-analysis or com method. This method is carried out systematically following the correct stages or research protocols. The source was taken from the PubMed site, and the Google Scholar site with journals published in 201 7-2022 and then filtered the results as many as 15,486. Results: Journal clustering was carried out and obtained the number of journals indexed in Scopus Q1 as many as 2 journals, Q2 as many as 2 journals, indexed Sinta S1 as many as 1 journal, so that there were 5 extracted journals. Conclusion: The majority of journals discuss age and lifestyle associated with the characteristics of panic disorder, as well as the factors of hyperthyroidism determined by age, and hyperthyroidism associated with panic disorder, ECG picture of sick node dysfunction.</p> <p><strong>Keywords:</strong><em> Characteristics Patients, Hyperthyroid</em>, Panic disorders, Sick Nodus Dysfunction<em>, </em>Hyperthyroidism.</p> R. Mohamad Javier 1*, Satrio Wicaksono 2, Basyar Adnani 3, Nabila Ramadina 4, Kelvin Florentino Kaisar 5, Moh Iqbal Setiawan 6, Arief Dewantara 7, Asti Yumna Adiningrum 8, Vania Putri Salsabilla 9, Budi Prakoso 10, Pertiwi Febriana Chandrawati 11, Subandono Bambang Indrasto 12 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-19 2024-01-19 19 01 PROLANIS PROGRAM (DIET, MEDICATION, AND PHYSICAL ACTIVITY) ON GLYCEMIC CONTROL OF TYPE 2 DM PATIENTS IN MAKASSAR CITY https://www.acgpublishing.com/index.php/CCB/article/view/229 <p><strong>Background</strong>: Blood sugar levels in people with diabetes can be controlled by managing a healthy diet and doing physical exercise. Diabetes mellitus treatment is one of the treatments included in the National Health Insurance (JKN) program in Indonesia. In the JKN era, the Diabetes Mellitus type 2 Chronic Disease Management Program was made one of the programs of the BPJS which was renamed the Program Pengelolaan Penyakit Kronis (Prolanis).</p> <p><strong>Aim:</strong> Knowing prolanis program (diet, medication, and physical activity) on glycemic control of type-2 DM patients</p> <p><strong>Method:</strong> The study was conducted in November 2023-Januari 2024 at Puskesmas Kassi-Kassi and Puskesmas Kalukubodoa. The number of samples at Puskesmas Kassi-Kassi was 183 people, and Puskesmas Kalukubodoa was 168 people with a total sample of 351 people with quantitative research methods using questionnaires.</p> <p><strong>Results:</strong> Based on the results of research conducted on 351 respondents, it can be explained that there were more respondents with a good diet, namely (92.6%), taking medicine according to doctor's recommendations, namely (91.2%). Respondents with moderate physical activity were (92.6%), and respondents with controlled glycemic control were more, namely (93.7%). The statistical test results obtained each p value = 0.000, this means that there is an effect of diet, medication, and physical activity (gymnastics) on the glycemic control of patients with type-2 diabetes.</p> <p><strong>Conclusion</strong>: In the prolanis program, there is an effect of diet, medication, and physical activity (gymnastics) on the glycemic control of type-2 DM patients in Makassar City.</p> <p><strong>Keywords:</strong> Diet, Medication, Physical Activity (Gymnastics), Glycemic Control, Type-2 DM</p> Sheinni Paradise1*, M. Alimin Maidin1, Amran Razak2, Abdul Rahman Kadir3 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-05 2024-03-05 19 01 225 235 IMPACT OF RESONATING FREQUENCIES OF SOUND WAVES ON LOWER BACK PAIN RELATED TO VERTEBRAL MALALIGNMENT https://www.acgpublishing.com/index.php/CCB/article/view/307 <p class="paperbody" style="margin-bottom: 0cm; line-height: 115%;"><span style="font-size: 12.0pt; line-height: 115%; color: windowtext;">Lower back pain is a prevalent global health concern, with the incidence escalating due to an aging and expanding world population. This study aims to evaluate the efficacy of resonating sound waves in alleviating lower back pain associated with vertebral malalignment. A purposive non-probability sampling technique was employed to recruit participants aged 25 to 75 years, experiencing lower back pain linked to vertebral malalignment. The inclusion criteria encompassed mechanical etiologies, such as disc and nerve-related pain, while visible causes like infection, trauma, and tumors (organic causes) were excluded from the study. IBM SPSS and Microsoft Excel were utilized for data entry, graphing, and tabulation. The findings reveal a robust positive trend in reducing pain scores for patients undergoing pulsar treatment (P &lt; 0.001). X-ray analyses demonstrated adjustments to disc spacing, facilitating vertebral realignment into a stable position. A comparison of pre- and post-treatment Numerical Pain Rating Scale (NPRS) scores revealed that resonating sound waves significantly improved pain relief in individuals suffering from chronic lower back pain. This study contributes to the growing body of evidence supporting the potential of resonating sound waves as an effective intervention for alleviating lower back pain associated with vertebral malalignment, thereby addressing a significant global health challenge.</span></p> <p class="paperbody" style="margin-bottom: 0cm; line-height: 115%;"><strong><span style="font-size: 12.0pt; line-height: 115%; color: windowtext;">Keywords</span></strong><span style="font-size: 12.0pt; line-height: 115%; color: windowtext;">: Mechanical low back pain, Pulsar treatment, Resonating frequencies, Sound waves, Vertebral malalignment</span></p> Nimra Batool1, Mehrun Nisa1, Faheem Afzal2, Afzal Hussain3, Muhammad Saeed Ahmad4, Saima Batool1, Youssra Ashgar1, Asma Munir1, Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-28 2024-03-28 19 01 434 442 DIAGNOSIS OF THE PLANT BIODIVERSITY OF AN ANTHROPOGENIC ZONE IN ALGIERS: CASE OF THE BOUZARÉAH FOREST MASSIF https://www.acgpublishing.com/index.php/CCB/article/view/400 <p>The flora of peri-urban forests is usually understudied compared to other forest types. This flora harbors a plant biodiversity that deserves better understanding. The Bouzaréah forest massif is a geographical area that boasts high biological diversity. It possesses a rich and diverse flora, the characteristics of which need to be determined for sustainable management. Over the decades, this area has experienced continual regression, mainly due to a combined action of climatic, ecological, and anthropogenic factors. 65 phytosociological surveys were conducted in the study area. Plant groups were determined using a modified TWINSPAN classification. For each vegetation group, diagnostic species were selected based on their fidelity index (phi coefficient). We identified 7 plant groups and selected 69 diagnostic species. Results obtained and verified through field investigations show that group 5, a shrubland located on the north-facing slope where conditions are favorable, is the richest and most diversified in plant species compared to other groups. Given the alarming degradation of ecosystems by humans and the current context of climate change, understanding the floristic diversity, structure, and characteristics of different floristic groups is crucial for effective management of urban forest spaces.</p> <p><strong>KEY WORDS</strong>: -Structure, Forest formations, Bouzaréah forest massif, Algeria.</p> Safia Abla 1*, Mohammed Djebbouri3, Sabrina Kefil 1, 2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-14 2024-04-14 19 01 520 536 POTENTIAL IMPACT OF CARBON TAX IMPLEMENTATION ON THE AGRICULTURE SECTOR IN INDONESIA, SPECIFICALLY THROUGH CARBON TAX IMPOSITION ON ENERGY USE https://www.acgpublishing.com/index.php/CCB/article/view/824 <p>Indonesia has agreed to comply with the Paris Agreement, which includes a commitment to restrict and control emissions of greenhouse gases (GHGs). The commitment is reinforced by the submission of the Enhanced NDC document mandating the higher emission reduction target in each scenario. The instrument of carbon pricing to implement soon is carbon tax, which is applied to emissions resulting from energy consumption. The agriculture sector, a substantial component of Indonesia’s economy, is experiencing growth as a result of revitalization through mechanization revolution leading to a heightened reliance on energy consumption. These arguments indicate that although the carbon tax is a component of Indonesia’s efforts to decrease greenhouse gas emissions, its impact on the agriculture sector must be cautiously controlled. The objectives of this study are to: 1. Estimate the potential revenue from carbon tax across all sectors, including agriculture; 2. Estimate the impacts of implementing carbon tax on the performance of the agriculture sector, including output, employment, and income levels. The result shows that the potential carbon tax revenue in Indonesia from all economic sectors is IDR 5,025,641,983,076.-. The agricultural sector has the potential to generate tax revenues of IDR 418,242,180.-. These are vary small compared to others’ most practices. There is a potential decline in the level of agricultural sector output of IDR 16,366.3 million and employment of 17,884,082 workers. At the subsector level, the largest decline for both indicators occurred in the Non-edible crops subsector. In terms of income, there is a potential decline as much as IDR.26,656.76 million. The distribution pattern of income reduction between classes due to the tax burden tends to be progressive. On the other hand, the intensity of income decline in each class tends to be regressive. Thisresults recommend that there should be mitigation in implementing the carbon tax in Indonesia using any appropriate strategies.</p> <p><strong>Keywords:</strong> agriculture, carbon tax, output, employment, income, regressive</p> Syahrituah Siregar1*, Luthfy Fatah2, M. Handry Imansyah2, Sunardi2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-10 2024-05-10 19 01 694 713 THE POSITIVE EFFECT ON THE PLANT AND YIELD BY TREATING WHEAT SEEDS WITH SALT WATER https://www.acgpublishing.com/index.php/CCB/article/view/844 <p>Salt stress often causes serious problems in wheat production areas. Salinity is one of a major threat in harvesting good wheat stand. In this study, potential of seed priming techniques to improve the performance of wheat&nbsp; in a saline field was tested. this&nbsp; is seed priming is a technique which is used to improve seed germination&nbsp; in field.&nbsp; Results indicated that wheat sown under&nbsp; effects of sea water&nbsp; An experiment was conducted on the Seed wheat For priming, wheat seeds were soaked in sea water solution . For comparison,&nbsp; also&nbsp; untreated seeds were also taken as control. Seed priming treatments. Seeds were primed for 6,12&nbsp; and 24 hours at three concentration sea water (salinity of water) (25, 50 ,75 and 100)&nbsp; and distilled water as control). Maximum seed germination percentage in lower dilutions&nbsp; was observed when the seeds primed by 0.0,25,50 dilutions of sea water, The most stem length was obtained for seeds .&nbsp; Maximum (MGT) of wheat&nbsp; was obtained from seeds primed with sea water 25 and 50found the increases, value germination was improved increases on lower concentration 25,50 include control.</p> <p><strong>Keywords: </strong>wheat, triticum aestivum<em>, </em>Salinity of water priming, salt stress, root,shoot.</p> Aiad Abdelkareim Akhreim Alzway, Ghazala Ahmad Hamaden Mansour Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-06-13 2024-06-13 19 01 934 956 TRADITIONAL POSTPARTUM CARE PRACTICES IN SEVERAL ASIAN COUNTRIES: A SYSTEMATIC REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/860 <p><strong>Background: </strong>Traditional postpartum care practices in several Asian countries have become an important part of local culture and heritage but have not been studied systematically.</p> <p><strong>Objective: </strong>This study aimed to restructure the existing information regarding traditional postpartum care practices in Asian countries to provide a more comprehensive understanding.</p> <p><strong>Methods: </strong>A systematic review involved five stages: identifying the research question, identifying relevant studies, selecting studies, charting data, collating, summarizing, and reporting results. To identify relevant studies, a systematic search was conducted using the PubMed, SCOPUS, Google Scholar, and Proquest databases for articles published between 2013 and 2023. Data from the included studies were charted using a standardized data extraction form. The form includes information on the Subject, Country, Findings.</p> <p><strong>Results:</strong> The findings show that traditional postpartum care practices in West and East Asia include avoiding certain foods, limiting activities to bed rest in South Asia and Central Asia, and that postpartum mothers apply unsafe practices based on cultural beliefs because of the costs and lack of awareness. In Southeast Asia, in general, they adhere to the traditional understanding of health and disease in the postpartum period, which is centered on warming the body, steaming through diet, and other heat applications, which are understood as ways of preventing postpartum disease. They carried out this practice to respect traditions and follow the advice of their parents.</p> <p><strong>Conclusion:</strong> The postpartum care practices of Asian countries vary regionally, posing potential risks. Improving standards and collaboration, focusing on women's education and local maternal–child health service providers, is crucial for improving maternal health.</p> Nurdiana Lante, Muh. Syafar, Syamsuar Manyullei, Yahya Thamrin, Shanty rizkiyani, Andi Nilawati Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-22 2024-07-22 19 01 1106 1123 CLINICAL CHARACTERISTICS, HEMATOLOGICAL VARIATIONS AND BIOACCUMULATION OF HEAVY METALS IN BLOOD, HAIR AND URINE OF BREAST CANCER PATIENTS https://www.acgpublishing.com/index.php/CCB/article/view/876 <p>Breast cancer is an important reason of cancer related mortality in females, account for 15.0% of such fatalities. Hematological changes are frequently considered with disease. Research identified potential link between fluctuations in heavy metal metabolism and progression. This study aimed to evaluate clinical characteristics, hematological variations, and heavy metal accumulation in breast cancer patients. Data were gathered from Jinnah Hospital Lahore using a questionnaire designed to collect clinical information from patients. Participants provided informed consent before data collection. Blood, hair, and urine samples from both control and case groups were obtained and analyzed for hematological changes and metals accumulation. The study found average age of people was 48.9 years, with significant changes noted in stage III patients. Variations in ER, PR, and HER2 status were observed among patients. Significant differences were found across all age groups. The incidence of breast cancer was notably higher in Lahore compared to other cities. Hematological parameters differed significantly between control and affected individuals, and there were notable variations in metal concentrations across sample types. In summary, there was a higher incidence of invasive ductal carcinoma among females, particularly in Lahore and other urban areas. Significant variations in hematological parameters and heavy metal concentrations were observed, including lower iron levels in blood and hair and decreased zinc levels across all samples among cases play role in cancer Nickel levels are higher among cases but remain within safe limits, and lead levels were low, indicating lead may not be a significant factor in this study</p> Rimsha, Kinza Khalid, Navida, Muhammad Farhan, Muhammad Gulzada, Maryam Afzal, Yusra Iqbal, Anum Saleem, Fouzia Tanvir, Yasir Nawaz, Saba Munir, Khazina Rafee Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-10 2024-08-10 19 01 1396 1411 EVALUATION OF ANTIMICROBIAL AND ANTICANCER EFFICACY OF PURIFIED SERRAPEPTASE ENZYME https://www.acgpublishing.com/index.php/CCB/article/view/898 <p>Background: Proteolytic enzymes have been used for different therapeutic purposes. Serrapeptase has versatile authenticated applications due to its immense properties. Our study aimed to investigate the antibacterial and anticancer effect of serrapeptase enzyme.</p> <p>Methods: Serrapeptase was purified from the supernatant of bacterial culture and precipitated using ammonium sulfate. Antibacterial activity was assessed against multiple bacterial strains by microdilution method. Anticancer activity of serrapeptase against three cancer cell lines (A549, Caco, MCF7) was evaluated by measuring cytotoxicity through MTT assay. Serrapeptase induced apoptosis was assessed by measuring activity of caspase-3 and flow cytometry measurement using annexin kit.</p> <p>Results: The lowest MIC (minimum inhibitory concentration) of serrapeptase was for <em>K. pneumonia </em>(2.94 µg/mL) while the highest values were for <em>P. aeruginosa</em>, and MRSA (MIC= 47 µg/mL). <em>S. aureus, E. coli, S. enterica, P. mirabilis</em>, and <em>C. albicans</em> had the same MIC (5.88 µg/mL). MTT assay showed that the lowest IC<sub>50</sub> (half-maximal inhibitory concentration) values were for A549 and MCF7 cell lines (IC<sub>50</sub> =1.59 µg/mL and 1.15 µg/mL respectively). Assessment of apoptosis revealed increase caspase-3 activity and percentage of early apoptotic cell in treated A549 and MCF7 cell lines.Conclusion: This study showed promising effects of serrapeptase as an antibacterial and anticancer agent that need to be validated by more in-vivo and mechanistic studies</p> Dalia Elebeedy, Aml Ghanem, Marwa El-Sayed, Ingy Badawy, Alya Redhwan, Mashail A. Alghamdi, Tahani M. Alqahtani, Enas A. Almanzalawi, Majid Al-Zahrani, Asmaa S. Abdelgeliel Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-27 2024-08-27 19 01 1530 1544 ASSESSING THE ROLE OF PHARMACISTS IN MANAGING CONTRAST MEDIA REACTIONS DURING RADIOLOGICAL PROCEDURES: A NURSING PERSPECTIVE https://www.acgpublishing.com/index.php/CCB/article/view/915 <p>Contrast media reactions are a potential complication during radiological procedures, and effective management is crucial for patient safety. This study aimed to assess the role of pharmacists in managing contrast media reactions from the perspective of nursing staff. A cross-sectional survey was conducted among nurses working in radiology departments across multiple healthcare facilities. The survey evaluated nurses' experiences with contrast media reactions, their perception of pharmacists' involvement in managing these reactions, and the perceived benefits and challenges of pharmacist-nurse collaboration in this context.</p> <p>The survey results indicated that nurses frequently encounter contrast media reactions and value the expertise of pharmacists in managing these events. Nurses reported that pharmacists' involvement in patient assessment, medication selection, and monitoring contributes to improved patient outcomes and increased nursing confidence in managing reactions. However, challenges such as limited pharmacist availability and communication barriers were identified. The findings suggest that enhancing pharmacist-nurse collaboration and defining clear roles and protocols can optimize the management of contrast media reactions and improve patient safety in radiology departments.</p> Abdulmajeed Khaled Al Anazi, Ahmed Hamed Hamid Almutairi, Ahmad Mohammad Al Farhoad, Mansour Ibrahim Mohammed Bin Hussein, Mohammed Mubarak Al Hasinah, Saeed Faiz Joyed Alaklabi, Sultan Mohammed Mousa Sadili, Yousef Mastour Al Anazi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-03 2024-10-03 19 01 1727 1737 DOCUMENTATION OF FOLK KNOWLEDGE ON WILD EDIBLE PLANTS OF RAMPACHODAVARAM AGENCY DIVISION, ANDHRA PRADESH, INDIA https://www.acgpublishing.com/index.php/CCB/article/view/192 <p>Folklore medicinal uses of 23 species of Wild edible plants belonging to 21 genera of 20 families for various ailments among the tribes of Rampachodavaram or Rampa agency division of Alluri Sitharama Raju (ASR) district, Andhra Pradesh is reported along with local name, mode of administration and prescribed doses. Local people use leaves, stem, flowers, fruits, seeds and roots as a part of their diet. Present study reveals the importance of 23 species of plants as they are eaten substantially by village folk as well as by city dwellers. It is desirable to bring these plants under organized agriculture as new crops to increase their production and utilization.</p> <p><strong>Keywords</strong>: Edible wild plants, Folk knowledge, Folk medicines, Tribal diet.</p> Pampayya Thanthati1, Dr. S. Sandhya Rani2* Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-03 2024-02-03 19 01 89 95 STUDY OF THE BACTERIAL ACTIVITY OF SILVER NANOPARTICLES (AGNPS) PRODUCED USING CYNOPHYTA ALGA EXTRACT (SPIRULINA PLATENSIS). https://www.acgpublishing.com/index.php/CCB/article/view/293 <p>The study included the production of biologically produced silver nanoparticles (AgNPs) by the algae extract <em>Spirulina</em> <em>platensis</em>, as well as the diagnosis of some effective chemical compounds from the blue-green algae <em>S</em>.<em>platensis</em> and the evaluation of the inhibitory effectiveness of silver nanoparticles (AgNPs) against some types of pathogenic bacteria that included <em>Escherichia</em> <em>coli</em>, <em>Pseudomonas</em> <em>aeruginosa</em> and <em>Staphylococcus</em> <em>aureus</em>.</p> <p>Different concentrations of silver nanoparticles (0.5, 1, 1.5 and 2) mg/ml were prepared to study their effect on the types of bacteria studied by determining the area of ​​diameter of bacterial growth inhibition. The silver nanoparticles showed their microbial effectiveness against two isolates of Gram-negative bacteria, <em>E.coli</em> and <em>P</em>.<em>aeruginosa</em> and the isolate of Gram-positive bacteria <em>S</em>.<em>aureus</em>, where the average diameter of the inhibition zone for the concentrations used was 12.58, 13.75 and 15.24 mm, respectively, by the diffusion well method. Bio-synthesized silver nanoparticles from the algae extract <em>S</em>. <em>platensis</em>, at very low concentrations, proved effective against the bacterial species studied.</p> <p>The results of drug susceptibility testing using the disk method showed that all bacterial isolates were 75% resistant to the antibiotics Amoxicillin, Chloramphenicol, Ciprofloxacin, Clindamycin, Trimethoprim/Sulfamethoxazole and Tetracyclin, while 25% were sensitive to the antibiotics Imipenem and Piperacllin/Tazobactam. The results of the drug susceptibility test using the Vitec system also showed that the <em>E.coli</em> bacteria were resistant to the antibiotics Ampicillin, Piperacillin/Tazobactam, Cefazolin, Cefoxitin, Ceftazidime, Ceftriaxone, Cefepime, Imipenem, Ciprofloxacin, Levofloxacin, Trimethoprim/Sulfamethoxazole at a rate of 73.3% , As for the antibiotics Amikacin, Gentamicin, Tigecycline and Nitrofurantoin, the sensitivity rate was 26.7%. As for the <em>P</em>. <em>aeruginosa</em> bacteria, it was 100% resistant to all antibiotics used. The <em>S</em>.<em>aureus</em> bacteria resisted the antibiotics Benzylpenicillin, Oxacillin, Ciprofloxacin, Erythromycin, Clindamycin, Tetracycline, Fusidic Acid and Rifampicin by 57.1%, while the antibiotics to which it was sensitive included Moxifloxacin, Linezolid, Teicoplanin and Trimethoprim/Sulfamethoxazole by 42%. 9%.</p> Dhuha Raheem Azooz Abbood1, Zainab Abd Ameer Mohammed2 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-19 2024-03-19 19 01 309 321 ASSOCIATION OF HISTOPATHOLOGICAL CHARACTERISTICS AND TERT (TELOMERASE REVERSE TRANSCRIPTASE) IMMUNOEXPRESSION WITH METASTATIC RATE IN CUTANEOUS MALIGNANT MELANOMA https://www.acgpublishing.com/index.php/CCB/article/view/668 <p>Cutaneous malignant melanoma (MM) is a malignant tumor with a high mortality rate. Histopathological characteristics are prognostic predictive factors of cutaneous MM, in which tumor thickness &gt;2 mm and mitotic rate ≥5/mm<sup>2</sup> correlate with a worse survival rate. A mutation in MM can occur at telomerase reverse transcriptase (TERT) promoter region, which leads to unlimited cell proliferation. Telomerase also increases metastatic risk. This study aims to determine the association between histopathological characteristics and TERT immunoexpression with metastasis in cutaneous MM. The study samples are 30 metastatic and 30 non-metastatic cutaneous MM in the Anatomical Pathology Department FKUI/RSCM, from January 2011 to July 2023. Histopathological characteristics (tumor thickness, mitotic index, lymphovascular invasion, and perineural invasion) were assessed, and anti-TERT antibodies were used for immunohistochemistry staining. Histopathological characteristics and TERT immunoexpression data were analyzed to determine their association with metastasis. Histopathological features that correlate significantly with metastasis are tumor thickness &gt;2 mm (p=0.006) and mitotic index ≥5 mitosis/mm<sup>2</sup> (p=0.008). Multivariate analysis showed a significant association between high TERT immunoexpression and metastasis in cutaneous MM (p&lt;0.001, aOR=56.1). This study concludes that high TERT immunoexpression increases the metastatic rate in cutaneous MM. Greater tumor thickness and a higher mitotic index are associated with metastasis in cutaneous MM.</p> <p><strong>Keywords: </strong>Cutaneous Malignant Melanoma; Immunohistochemistry; Metastasis; TERT</p> Riesye Arisanty 1, Bayu Perkasa Rosari 2*, Puspita Eka Wuyung 3, Maria Angela Putri Maharani 4 Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-04-22 2024-04-22 19 01 ASSESSMENT OF AQUATIC PHYSIO-CHEMICAL PARAMETERS OF SHIVNATH RIVER FROM DAGAURI VILLAGE ZONE BILASPUR CHHATTISGARH https://www.acgpublishing.com/index.php/CCB/article/view/832 <p>Water is a valuable essential and survive vital composition of universal Nature Biotic and abiotic life cycles . Surface river water has one Important for living society besides its habitats. However, there are various micro-organism ions and suspended particles, mineral dissolved components. According to the selected site of River water sample are main source of multiple purpose required for the daily human needs and all other activities. Shivnath river water is one of the major sources for domestic uses may part of dagauri village area. The present investigation deals with the study of chemical parameters , studies have in this river on different sites by a specially prepared. Aquatic assessment questionnaire chemicals &amp; inorganic meters. Water quality Index and various physio-chemical Analysis of river drinking water of Different 8 sites of Dagauri village zone Bilaspur had studied in Over a period of three months (Oct.-Dec. 2022) reading had observed to analyse different physio-chemical parameters Turbidity, Total Hardness (Mg &amp;Ca), COD &amp; BOD, pH the results were found in the range of 2.51–3.8&nbsp; NTU, 300-650 mg/l , 15.3-18.5 mg/l ,1.3-3.2 mg/l &amp; 7.0-8.1 pH value. Respectively while F, Cl, No3, So4 were in the range of 0.56-2.5 mg/l. 250-400 mg/l, 6-28 mg/l, and 12-40 mg/l . Iron and zinc&nbsp; heavy metal were present in range of 0.48-1.12 ml/l, 1.26-1.29 mg/l. The present study has it’s almost importance for hygienic point of view in the Public Interest and its consequence with respect to health hazard. Bilaspur district Dagauri village zone was selected for the purpose of Investigation many illiterate villagers and use of surface river water&nbsp; for their drinking purpose &amp; domestic activity.</p> <p><strong>Keyword- </strong>&nbsp;Public health, Aquatic environment,&nbsp; Physio-chemical, Investigation</p> K.C. Gendle, M. R. Augur, P.K. Singh Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-05-24 2024-05-24 19 01 788 800 STUDY OF THE EFFECT OF TEMPERATURE ON THE STABILITY CONSTANT OF A NUMBER OF AZO DYES FORMED FROM A REAGENT REACTION (O- PHENYLENE DIAMINE) WITH SOME CHALCONES https://www.acgpublishing.com/index.php/CCB/article/view/851 <p>Our work involves a spectroscopic investigation of how pH affects the thermodynamic production of azo dyes, which are created when certain chalcones react with the isotactic reagent ortho-phenylenediamine at the dye's natural acid function at a fixed temperature (298 K). We looked at the ideal circumstances for every created azo dye &nbsp;along with the optimal molar ratios of its component parts, which were (2:1) for the reagent to the chalcone.</p> <p>For the produced azo dyes, the stability remained constant throughout three acidic levels and six temperature ranges (273, 283, 293, 303, 313, 323 K). Then we found stability constants at the six temperatures mentioned above, It enabled us to determine that, based on the negative values of (ΔG° and ΔH), respectively, the reactions that generate azo dyes are spontaneous and heat-emitting.</p> Hiba Salah Ahmeed, Ebtahag Z. Sulyman, Mohammad Mahmoud Hussein Al-Niemi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-07-05 2024-07-05 19 01 1021 1031 NURSING EDUCATION ON PHARMACOLOGICAL INTERVENTIONS https://www.acgpublishing.com/index.php/CCB/article/view/867 <p>Core drug knowledge also includes pharmacotherapeutics, pharmacokinetics, pharmacodynamics, contraindications and precautions, side effects, and drug interactions. It also includes basic pharmacologic information about each drug. Core patient variables are the traits that make a patient stand out at any particular time. (Maciej Serda et al., 2012)</p> <p>However, in critical care units (ICUs), intensive care nurses are always on hand to supervise the patient's care and keep an eye on their condition. The foundation of contemporary intensive care is interprofessional collaboration. According to Henderson (1966), a nurse's general goal is to assist patients in meeting their basic needs while they are in precarious situations and to aid in their transition to independence.(Harris, Godoy and Nathe, 2014; Larsen, Johannessen and Heggdal, 2022). Drug-related issues, especially the safe transfer of the drug regimen, have been recognized as crucial elements of high-quality therapy in transitional care. Programs for transitional care may help to reduce medication-related problems, improve access to medication therapy, provide in-depth medication counselling, and fill in medication care gaps following hospital discharge. (Mardani, Griffiths and Vaismoradi, 2020). The nurse chooses which of the patient's primary qualities are crucial for a particular pharmacological therapy. They include things like genetic characteristics, life expectancy, gender, lifestyle, food, and daily routines. Which major interactions between the fundamental patient characteristics and the fundamental drug information will occur is decided by the nurse. The nurse then makes recommendations based on such interactions to improve the therapeutic benefit and decrease adverse effects related to pharmaceutical therapy. The nurse incorporates these strategies into a nursing plan of care. (Maciej Serda et al., 2012). Traditionally, nurses have been in charge of preparing and dispensing medications under the direction of doctors. However, as tasks have shifted from doctors to nurses over the past few decades, nurses' roles have increased. (Maier and Aiken, 2016; De Baetselier et al., 2022). Nurses’ roles have expanded in the past years for more duties than the ordinary ones. This includes pharmacological intervention and medication management. There is a lack of knowledge of these roles and duties<strong>. </strong></p> Ahmad Asheq M. Abinayesh, Awwad Qahyem Mashaan Alshammary, Ahmad Salem Mutlaq Alkhaldi, Eid Nawaf Hatl Alanazi, Ali Abdoh Ali Alshaikhi Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-01-20 2024-01-20 19 01 1192 1203 SEASONAL ABUNDANCE OF SOIL ARTHROPODS IN FOREST AND AGRO ECOSYSTEMS IN WARANGAL DISTRICT, TELANGANA STATE, INDIA https://www.acgpublishing.com/index.php/CCB/article/view/885 <p><em>&nbsp;</em><strong>ABSTRACT</strong>Soil arthropods play a crucial role in ecosystem functioning and their populations are influenced by seasonal and ecological factors. This study aimed to investigate the seasonal variations in the abundance of soil arthropods in forest and agro-ecosystems within Warangal district, Telangana, India. Soil samples were collected from two 10-acre sites—an agricultural field and a forest area—across three seasons: Summer, Monsoon, and Winter. Tullgren funnels were used to extract and identify arthropods, with their abundance recorded and analyzed for seasonal trends. Results indicated that Collembola was the most abundant order in the forest ecosystem throughout the year, with significant peaks during the Monsoon, while the agro-ecosystem showed higher abundance of Collembola and Orthoptera in the Monsoon. Protura and Thysanura were also more prevalent in the forest during Winter, and seasonal fluctuations were more pronounced in the agro-ecosystem. These findings highlight the differential impacts of seasonal changes on arthropod communities in various ecosystems, emphasizing the stability of forest environments compared to the more dynamic agro-ecosystems.</p> Lakshmi Merugu, Esam Narayana Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-16 2024-08-16 19 01 1440 1449 PREVALENCE OF DOMESTIC INTIMATE PARTNER VIOLENCE AMONG SELECTED CEBUANO WOMEN AND ITS RELATIONSHIP TO THEIR DEMOGRAPHICS https://www.acgpublishing.com/index.php/CCB/article/view/906 <p><strong>Abstract</strong> - Women often feel pressured to be married as one of the “toxic Filipino cultures” which includes not preparing them for realistic marital and familial problems that could arise, especially concerning domestic intimate partner violence. This research paper aims to determine the existence of a relationship between selected Cebuano women’s demographics and forms of domestic intimate partner violence (DIPV) from three (3) cities in Cebu: Cebu City, Mandaue City, and Lapu-Lapu City utilizing descriptive correlational survey design. Using Haj-Yahia's Questionnaire of Violence Against Women, ninety-nine (99) respondents gave consent to participate and answer the survey. The results found that the most prevalent form of abuse is physical abuse and the only demographic that has a relationship to the forms of abuse is selected Cebuano women’s educational attainment and its relation to sexual and economic abuse. These findings were analyzed with the use of descriptive statistics, frequency distribution, and chi-square. The implications of this study are significant to policymakers to show immediate action, future researchers to encourage them to research more on DIPV in the Philippines, and to other young women to be aware of DIPV.</p> Ma. Magdalena C. Cataraja, Crizarah L. Guisadio, Shavy I. Abella, Mary Alwina S. Tabasa, Jelyn L. Cabague, and Ronald C. Yrog-Irog Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-09-12 2024-09-12 19 01 1626 1640 BUILDING FAITH AND WEALTH: ECONOMIC OPPORTUNITIES ARISING FROM RAM MANDIR https://www.acgpublishing.com/index.php/CCB/article/view/924 <p>This paper explores the intricate relationship between religious development and socioeconomic growth in the context of the Ram Mandir project in Ayodhya, Uttar Pradesh. Utilizing data collected from 500 respondents within the local community, this study investigates the perceived economic opportunities and the potential for wealth generation stemming from the temple’s construction and its subsequent role as a pilgrimage site. The findings reveal a strong correlation between faith-based tourism and economic upliftment, with respondents highlighting various avenues for income generation, including hospitality services, local crafts, retail, and transportation.</p> <p>The research illustrates that the Ram Mandir not only serves as a spiritual symbol for millions but also as a catalyst for economic revitalization in Ayodhya. Respondents expressed optimism regarding job creation and the inflow of tourists, which is expected to bolster local businesses and enhance overall community development. Furthermore, the paper delves into the role of community engagement, with local stakeholders actively participating in planning discussions to ensure that the economic benefits of the temple’s establishment are equitably distributed.</p> <p>By employing a qualitative interviews, this paper provides a comprehensive overview of local perceptions regarding the Ram Mandir’s impact on economic growth. The results underscore the significance of integrating religious and economic initiatives to foster sustainable development in culturally rich areas. Ultimately, this study contributes to the broader discourse on faith and economy, illustrating how spiritual landmarks can generate substantial economic opportunities while simultaneously reinforcing community identity and heritage.</p> Samdish Sharma, Dr. M.R Behera Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-10-21 2024-10-21 19 01 1876 1900 DANGEROUS HEAVY METAL POLLUTION AND NITRATE AND PHOSPHATE CONCENTRATION CONTAINED IN THE SEAWEED THALLUS (Kappaphycus Alvarezii and Gracilaria Verrucosa) https://www.acgpublishing.com/index.php/CCB/article/view/210 <p><em>Kappaphycus alvarezii</em> seaweed is a key local commodity in Central Sulawesi. However, since 2012, its production has drastically decreased, especially in mining exploration centers such as the coastal waters of Morowali Regency and Palu Bay. Mining activities, including nickel mining in Morowali, gold mining in Poboya, and other mining operations in Palu, have led to changes in land use, transforming areas into mining concessions. This situation raises significant concerns as both mining commodities and seaweed are crucial regional assets for driving the local and national economy. Mining activities have resulted in a substantial reduction in the area of <em>Kappaphycus alvarezii</em> cultivation in Morowali Regency, decreasing from 78,420 ha in 2011 to 8,410 ha in 2014. Data from the Central Sulawesi Provincial Fisheries Service reveals a significant decline in dry <em>Kappaphycus sp</em> production from 2016-2020, reaching 383,360 – 59,129 tons/year, with no production expected in 2021. Similarly, E. spinosum and <em>Gracilaria sp</em> production have also experienced declines from 2018-2021. The results of the research show that the nickel content in the thallus of seaweed along the Morowali waters is very high and can be dangerous and is thought to be the cause of the extinction of the seaweed.</p> <p><strong>Keywords</strong>: Seaweed, Mining, Exploitation, Extinction</p> Zakirah Raihani Ya’la,Ali Husni , Tri Joko Santoso, Triyani Dewi , Marhawati, Maemunah, Eka Rosyida, Samliok Ndobe, Faisal Haris Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-02-21 2024-02-21 19 01 CURRENT TREND IN LAMIACEAE AS A RESPONDING TO NATURAL ELICITORS SPRAYING: FOCUSING ON NATURAL PRODUCTS AND PLANT STRESS. A MINI NARRATIVE REVIEW https://www.acgpublishing.com/index.php/CCB/article/view/305 <p>Lamiaceae is the largest family in the order Lamiales, with 236 genera and over 7,000 flowering plant species. Known as the mint family, it is important for its aromatic leaves and medicinal properties. Stresses affect plant physiology, prompting the production of secondary metabolites. Elicitors accelerate secondary metabolite formation in plants. By the present review, Web of Science, Scopus, Google Scholar, PubMed and Science Direct databases were referred to collect information about natural elicitors (amino acids, polyamines, yeast, seaweeds and plant extracts). This present work reviewed the literature from 2015 to march 2024. The aim of this work is to highlight the recent in the impact of natural elicitors on secondary metabolite accumulation and plant stress in Lamiaceae. Foliar spraying of natural elicitors induced changes in plants, such as increased volatiles accumulation and alterations in essential oil composition, phenolic contents, and total flavonoids, as well as antioxidant enzymes. Variations in growth, oil composition, and yield were observed in different plant species in response to drought and salinity stress. The plants adapted by changing their physiological activities to produce secondary metabolites. Spraying Natural elicitors effectively reduces the damage of oxidative stress and mitigates the negative effects of salinity, water deficit, and heavy metals on secondary metabolites in plants of the Lamiaceae family, leading to plants of this family adapting to conditions of various environmental stresses. Review showed that focusing on <em>Ocimum</em> genus; importance of studying various biological extracts especially on plant extracts on Lamiaceae genus, including diverse species like Chia (<em>Salvia hispanica</em> L.).</p> <p>Keywords: <em>Lamiaceae</em>, Natural- Elicitors, Foliar spraying, Secondary Metabolites, Plant Stress.</p> Ismail M. A. M. Shahhat* Copyright (c) 2024 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-03-27 2024-03-27 19 01 405 421 STUDYING METHODS TO MONITOR AND EVALUATE THE SAFETY OF DRUGS POST-MARKET, INCLUDING ADVERSE DRUG REACTIONS https://www.acgpublishing.com/index.php/CCB/article/view/127 <p>The safety of drugs post-market is a crucial aspect that must be carefully monitored and evaluatedto ensure the well-being of patients. Adverse drug reactions (ADRs) can have seriousconsequences, and it is important to have effective methods in place to detect, assess, and managethese reactions. This paper explores various studying methods used to monitor and evaluate thesafety of drugs post-market, with a specific focus on adverse drug reactions. The methodology,results, and discussion of these methods are presented to provide a comprehensive overview of thetopic</p> Mohammed Nuwaymi Toma Aljaberi, Asma Ibrahim Al Zayn, Talal Tail Alsulami, Mohammad Saleh Abdullah Alamri, Saad Mohammed Awwadh Alshalwi, Fahad Noor Faleh Alasadi, Nader Essa Subayyil Alotaibi and Ali Abdullah Ahmed Alqarni Copyright (c) 2023 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 2024-08-07 2024-08-07 19 01 1371 1375