https://www.acgpublishing.com/index.php/CCB <h1>About Chelonian Research Foundation</h1> <p align="justify">Chelonian Research Foundation, established in 1992 in Lunenburg, Massachusetts, is a non-profit IRS-designated 501(c)(3) tax-exempt private operating foundation established for the purposes of producing and publishing scientific research on turtles and tortoises of the world, as well as supporting worldwide turtle and tortoise research through charitable distributions to associated independent scientific investigators or research organizations that produce specific research consistent with the stated objectives of the Foundation. The Foundation was established partly in response to the rapidly deteriorating natural environment and its deleterious effects on populations of turtles and tortoises of the world as well as the threatening effects of direct human exploitation on turtles and tortoises around the world, and partly in response to the global need for systematic scientific investigations and documentation of the diversity of these animals. The broad purpose of the Foundation is to become involved where the energies of concerned and talented individuals and the application of resources may reasonably be anticipated to provide a scientific basis to allow for potential improvement in conditions or increased understanding of turtles and tortoises.</p> <p align="justify"> </p> en-US Wed, 23 Jul 2025 11:03:53 +0000 OJS 3.3.0.7 http://blogs.law.harvard.edu/tech/rss 60 https://www.acgpublishing.com/index.php/CCB/article/view/718 <p><strong>Background</strong>. Traditional herbal medicine has been effectively used to treat various diseases for hundreds or even thousands of years, as mentioned in ancient manuscripts, textbooks, and pharmacopoeias. Since ancient times, herbal therapy has played a crucial role in combating infectious diseases. BPOM distribution permits are needed to maintain the safety of drugs in circulation. A distribution permit is a permit for Drugs and Food produced by manufacturers and/or imported by importers of Drugs and Food that will be distributed in the territory of the Republic of Indonesia based on an assessment of safety, quality, and usefulness.</p> <p><strong>Aims</strong>. This study aims to investigate the legal process of HV Care as an antiviral, as per the Indonesian Food and Drug Control Agency (BPOM).</p> <p><strong>Method.</strong> The experimental method is used in the research, from preparing raw materials to processing, until it becomes a finished product, followed by the legal process to obtain a distribution permit.</p> <p><strong>Result. </strong>The herbal medicine formulation utilizes extracts obtained from vendors who have already received certification from BPOM. The raw materials are then mixed according to the predetermined dose, mashed, sifted, and packaged into capsules. The distribution permit process is submitted to BPOM through various stages, including registration and laboratory results for the submitted formula, as well as the Standard Operating Procedure (SOP) for formula preparation.</p> <p><strong>Conclusion. </strong>HV Care is an herbal medicine with the composition of meniran (<em>Phyllanthus Urinaria Folium), </em>Temu mango (<em>Curcuma amada Rhizome), </em>Curcuma<em> Zanthorrhiza Rhizome, </em>Sambiloto (<em> Andrographis Paniculata Folium). It is helpful as an antiviral for HIV sufferers</em> in particular and other viral diseases. HV Care has been processed by the standards of the Indonesian Food and Drug Control Agency (BPOM) and holds a POMTR223008931 distribution permit, enabling it to be distributed in the community.</p> Retno Widyani, An Nuur Budi Utama, Rianty Aryani Putri Copyright (c) 2022 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 https://www.acgpublishing.com/index.php/CCB/article/view/718 Wed, 23 Jul 2025 00:00:00 +0000 https://www.acgpublishing.com/index.php/CCB/article/view/717 <p>Herbicides are essential in modern agriculture but pose severe risks to aquatic ecosystems, particularly fish. This review examines herbicides' biochemical and genotoxic impacts on fish species, addressing oxidative stress, metabolic disruptions, hormonal interference, DNA damage, and mutations. Herbicides like glyphosate, atrazine, paraquat, and 2,4-D have been linked to enzymatic inhibition, reproductive abnormalities, and genetic mutations with extensive implications for aquatic biodiversity and human health. Case studies provide further insights into specific herbicides' effects, such as glyphosate’s role in oxidative stress, atrazine's endocrine disruption, and paraquat’s genotoxicity. Continuous monitoring, regulation, and alternative solutions are crucial to reduce these harmful effects and protect aquatic life and public health.</p> Devika Rani H K, Parimala B Copyright (c) 2022 Chelonian Research Foundation https://creativecommons.org/licenses/by/4.0 https://www.acgpublishing.com/index.php/CCB/article/view/717 Wed, 23 Jul 2025 00:00:00 +0000